D27-pLpxL, an avirulent strain of Yersinia pestis, primes T cells that protect against pneumonic plague

scientific article published on 20 July 2009

D27-pLpxL, an avirulent strain of Yersinia pestis, primes T cells that protect against pneumonic plague is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00273-09
P932PMC publication ID2747924
P698PubMed publication ID19620344

P50authorEgil LienQ90239495
P2093author name stringFrank M Szaba
Jr-Shiuan Lin
Lawrence W Kummer
Stephen T Smiley
Lawrence L Johnson
Michelle A Parent
Lindsey B Wilhelm
Sara W Montminy-Paquette
P2860cites workIn vivo comparison of avirulent Vwa- and Pgm- or Pstr phenotypes of yersiniaeQ37097219
Vaccines against intracellular bacterial pathogensQ37206444
Cell-mediated protection against pulmonary Yersinia pestis infectionQ39393406
Expression of plasminogen activator pla of Yersinia pestis enhances bacterial attachment to the mammalian extracellular matrix.Q39573935
Antibodies and cytokines independently protect against pneumonic plague.Q41441607
A Yersinia pestis lpxM-mutant live vaccine induces enhanced immunity against bubonic plague in mice and guinea pigs.Q41446828
Vaccination with live Yersinia pestis primes CD4 and CD8 T cells that synergistically protect against lethal pulmonary Y. pestis infectionQ41451306
Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide responseQ41452286
Gamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infectionQ41453869
The anti-plague system and the Soviet biological warfare programQ41454361
Yersinia pestis V protein epitopes recognized by CD4 T cellsQ41459022
Plague, Democratic Republic of The Congo.Q41459174
Stat 4 but not Stat 6 mediated immune mechanisms are essential in protection against plagueQ41461188
Defining the genome content of live plague vaccines by use of whole-genome DNA microarrayQ41461622
The SCID/Beige mouse as a model to investigate protection against Yersinia pestisQ41483548
Multidrug resistance in Yersinia pestis mediated by a transferable plasmidQ41487671
Protection of mice from fatal bubonic and pneumonic plague by passive immunization with monoclonal antibodies against the F1 protein of Yersinia pestisQ41488613
A comparison of Plague vaccine, USP and EV76 vaccine induced protection against Yersinia pestis in a murine modelQ41493178
Loss of the pigmentation phenotype in Yersinia pestis is due to the spontaneous deletion of 102 kb of chromosomal DNA which is flanked by a repetitive elementQ41505380
Live, attenuated Yersinia pestis vaccine: virulent in nonhuman primates, harmless to guinea pigsQ41551949
Activated antigen-specific CD8+ T cells persist in the lungs following recovery from respiratory virus infectionsQ45738972
IMMUNITY IN PLAGUE. ACQUISITIONS SUPPLIED BY 30 YEARS OF WORK ON THE "PASTEURELLA PESTIS EV" (GIRARD AND ROBIC) STRAINQ76657056
Yersinia pestis CO92 delta yopH is a potent live, attenuated plague vaccineQ24672915
Yersinia pestis--etiologic agent of plagueQ29619320
Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidatesQ31037921
Immune defense against pneumonic plagueQ33584403
Human immune response to a plague vaccine comprising recombinant F1 and V antigensQ33788286
Plague as a biological weapon: medical and public health management. Working Group on Civilian BiodefenseQ33901607
Determination of the virulence of the pigmentation-deficient and pigmentation-/plasminogen activator-deficient strains of Yersinia pestis in non-human primate and mouse models of pneumonic plague.Q34128266
Yersinia pestis (plague) vaccinesQ34324211
Risk of person-to-person transmission of pneumonic plagueQ34406504
Administration of antibody to the lung protects mice against pneumonic plague.Q34601788
Differential clearance and host-pathogen interactions of YopE- and YopK- YopL- Yersinia pestis in BALB/c miceQ35094337
Suppression of cytokines in mice by protein A-V antigen fusion peptide and restoration of synthesis by active immunization.Q35429159
Development of in vitro correlate assays of immunity to infection with Yersinia pestis.Q35783560
Plasmid maintenance systems suitable for GMO-based bacterial vaccinesQ36065368
Protection from respiratory virus infections can be mediated by antigen-specific CD4(+) T cells that persist in the lungsQ36369221
Braun lipoprotein (Lpp) contributes to virulence of yersiniae: potential role of Lpp in inducing bubonic and pneumonic plague.Q36539626
Current challenges in the development of vaccines for pneumonic plagueQ36628038
Biological safety concepts of genetically modified live bacterial vaccinesQ36713988
Effectiveness of live or killed plague vaccines in man.Q36719644
Lipid A mimetics are potent adjuvants for an intranasal pneumonic plague vaccineQ36960814
Single-dose, virus-vectored vaccine protection against Yersinia pestis challenge: CD4+ cells are required at the time of challenge for optimal protectionQ37066697
Yersinia pestis evades TLR4-dependent induction of IL-12(p40)2 by dendritic cells and subsequent cell migrationQ37093215
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectYersinia pestisQ153875
P304page(s)4295-4304
P577publication date2009-07-20
P1433published inInfection and ImmunityQ6029193
P1476titleD27-pLpxL, an avirulent strain of Yersinia pestis, primes T cells that protect against pneumonic plague
P478volume77

Reverse relations

cites work (P2860)
Q34778198A live attenuated strain of Yersinia pestis KIM as a vaccine against plague
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Q35665414A protective epitope in type III effector YopE is a major CD8 T cell antigen during primary infection with Yersinia pseudotuberculosis
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Q36646741Deletion of the Braun lipoprotein-encoding gene and altering the function of lipopolysaccharide attenuate the plague bacterium.
Q93375305Escherichia coli expressed flagellin C (FliC) of Salmonella Typhi improved the protective efficacy of YopE against plague infection
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Q34633478HSP70 domain II of Mycobacterium tuberculosis modulates immune response and protective potential of F1 and LcrV antigens of Yersinia pestis in a mouse model
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Q47293934Immunisation of two rodent species with new live-attenuated mutants of Yersinia pestis CO92 induces protective long-term humoral- and cell-mediated immunity against pneumonic plague
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Q35530270Intranasal administration of an inactivated Yersinia pestis vaccine with interleukin-12 generates protective immunity against pneumonic plague
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