Mesenchymal stem cells as feeder cells for pancreatic islet transplants

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Mesenchymal stem cells as feeder cells for pancreatic islet transplants is …
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scholarly articleQ13442814

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P356DOI10.1900/RDS.2010.7.132
P932PMC publication ID2989786
P698PubMed publication ID21060972

P50authorLorenzo PiemontiQ37382584
P2093author name stringValeria Sordi
P2860cites workDonor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patientQ21090134
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimenQ28141785
Isolation of putative progenitor endothelial cells for angiogenesisQ28302884
Signals from the neural crest regulate beta-cell mass in the pancreasQ28511170
Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice.Q30478228
Mesenchymal stem cells can be differentiated into endothelial cells in vitroQ31063600
Successful islet transplantation: continued insulin reserve provides long-term glycemic controlQ31089312
Five-year follow-up after clinical islet transplantationQ33218078
Detection of 111In-oxine-labeled bone marrow stromal cells after intravenous or intralesional administration in chronic paraplegic ratsQ45275526
The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women: 20 years of follow-upQ45303554
Bone marrow-derived mesenchymal stem cells improve islet graft function in diabetic rats.Q45958465
Reduced insulin secretion and content in VEGF-a deficient mouse pancreatic isletsQ46382332
Hepatocyte growth factor is constitutively produced by donor-derived bone marrow cells and promotes regeneration of pancreatic beta-cellsQ46540500
Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experienceQ46582092
Bone marrow stromal cells can provide a local environment that favors migration and formation of tubular structures of endothelial cellsQ46584311
Combined islet and hematopoietic stem cell allotransplantation: a clinical pilot trial to induce chimerism and graft toleranceQ46620610
Improved metabolic control and quality of life in seven patients with type 1 diabetes following islet after kidney transplantationQ46687469
In vitro and in vivo improvement of islet survival following treatment with nerve growth factor.Q46958656
Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanismsQ47248012
Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanismsQ47945142
Cytogenetic analysis of human bone marrow-derived mesenchymal stem cells passaged in vitroQ48317427
Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis.Q50674319
Bone marrow (BM) transplantation promotes beta-cell regeneration after acute injury through BM cell mobilization.Q50700086
Spontaneous transformation of cultured mouse bone marrow-derived stromal cells.Q51104088
The vascular niche and its basement membrane.Q52674573
Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.Q53328521
Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation.Q53352599
International trial of the Edmonton protocol for islet transplantation.Q54032399
Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cellsQ57702376
Recruitment of Bone Marrow-Derived Endothelial Cells to Sites of Pancreatic -Cell InjuryQ57720869
Role of vascular endothelial growth factor in bone marrow stromal cell modulation of endothelial cellsQ73099605
Islet transplantation: a brave new worldQ73581830
Islet injury induces neurotrophin expression in pancreatic cells and reactive gliosis of peri-islet Schwann cellsQ74351838
A significant role for histocompatibility in human islet transplantationQ79955732
Enhanced epithelial gap closure and increased angiogenesis in wounds of diabetic mice treated with adult murine bone marrow stromal progenitor cellsQ80403767
High risk of sensitization after failed islet transplantationQ81227041
A novel human stem cell coculture system that maintains the survival and function of culture islet-like cell clustersQ82084196
Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing mediumQ82092596
ISSCR Guidelines for the Clinical Translation of Stem CellsQ83694599
Mesenchymal stem cells cooperate with bone marrow cells in therapy of diabetesQ33302407
Cellular islet autoimmunity associates with clinical outcome of islet cell transplantationQ33344421
Novel cell-free strategy for therapeutic angiogenesis: in vitro generated conditioned medium can replace progenitor cell transplantationQ33455791
Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in miceQ33570549
Bone marrow cell cotransplantation with islets improves their vascularization and function.Q33749301
Overcoming the challenges now limiting islet transplantation: a sequential, integrated approachQ34585184
Associations of diabetes mellitus with total life expectancy and life expectancy with and without cardiovascular diseaseQ34636629
Grafting of human bone marrow stromal cells into spinal cord injury: a comparison of delivery methods.Q34776506
Angiomyeloproliferative lesions following autologous stem cell therapyQ35153218
Mesenchymal stem cells enhance allogeneic islet engraftment in nonhuman primatesQ35757109
The therapeutic potential of neural stem cellsQ36500191
The development of diabetes in E2f1/E2f2 mutant mice reveals important roles for bone marrow-derived cells in preventing islet cell lossQ36689966
Allogeneic bone marrow supports human islet beta cell survival and function over six monthsQ36690685
Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularizationQ36842592
Immunomodulatory properties of mesenchymal stromal cellsQ36896799
Simultaneous islet and kidney transplantation in seven patients with type 1 diabetes and end-stage renal disease using a glucocorticoid-free immunosuppressive regimen with alemtuzumab inductionQ36906347
From endothelial to beta cells: insights into pancreatic islet microendotheliumQ37065881
Primary graft function, metabolic control, and graft survival after islet transplantationQ37269443
Trophic molecules derived from human mesenchymal stem cells enhance survival, function, and angiogenesis of isolated islets after transplantationQ39745012
Sarcoma derived from cultured mesenchymal stem cellsQ40220522
Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lungQ40233552
IL-6 protects pancreatic islet beta cells from pro-inflammatory cytokines-induced cell death and functional impairment in vitro and in vivoQ40544239
Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivoQ40662801
Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9Q42276892
Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet functionQ42463306
Regulation of human beta-cell adhesion, motility, and insulin secretion by collagen IV and its receptor alpha1beta1.Q42469169
Allosensitization of islet allograft recipientsQ42522778
VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cellsQ42677798
Mesenchymal stem cell and islet co-transplantation promotes graft revascularization and function.Q43009815
Mesenchymal stem cells prevent acute rejection and prolong graft function in pancreatic islet transplantationQ43063268
Immune modulation of co-transplantation mesenchymal stem cells with islet on T and dendritic cellsQ43067728
Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformationQ43208941
Neural crest stem cells increase beta cell proliferation and improve islet function in co-transplanted murine pancreatic islets.Q43262810
Bone marrow as an alternative site for islet transplantation.Q43272811
The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion.Q43599448
Autoantibody response to islet transplantation in type 1 diabetesQ43778767
Cell fusion is the principal source of bone-marrow-derived hepatocytesQ44383220
Postnatal bone marrow stromal cells elicit a potent VEGF-dependent neoangiogenic response in vivoQ44401503
Marginal mass islet transplantation with autologous mesenchymal stem cells promotes long-term islet allograft survival and sustained normoglycemiaQ45023273
Single-donor, marginal-dose islet transplantation in patients with type 1 diabetesQ45267369
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmesenchymal stem cellQ1922379
P304page(s)132-143
P577publication date2010-08-10
P1433published inThe review of diabetic studies : RDSQ26853988
P1476titleMesenchymal stem cells as feeder cells for pancreatic islet transplants
P478volume7