Overcoming the challenges now limiting islet transplantation: a sequential, integrated approach

scientific article

Overcoming the challenges now limiting islet transplantation: a sequential, integrated approach is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1196/ANNALS.1375.059
P698PubMed publication ID17130583

P50authorCamillo RicordiQ37383548
Antonello PileggiQ37387749
Lorenzo CobianchiQ56995754
Luca InverardiQ114419100
P2860cites workThe unique cytoarchitecture of human pancreatic islets has implications for islet cell functionQ24541464
Notch signaling controls multiple steps of pancreatic differentiationQ24569636
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiationQ29614736
Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopyQ30853783
Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets.Q31112565
Targeted bone marrow radioablation with 153Samarium-lexidronam promotes allogeneic hematopoietic chimerism and donor-specific immunologic hyporesponsivenessQ33199557
A novel method for the assessment of cellular composition and beta-cell viability in human islet preparationsQ33216707
Sirolimus-induced ulceration of the small bowel in islet transplant recipients: report of two casesQ33368841
Use of oxygenated perfluorocarbon toward making every pancreas countQ35033645
Development of a human pancreatic islet-transplant program through a collaborative relationship with a remote islet-isolation centerQ35668814
Clinical islet transplantation: advances and immunological challengesQ35730793
Delivery of proteins and peptides into live cells by means of protein transduction domains: potential application to organ and cell transplantationQ35808052
Requirements for success in clinical islet transplantationQ36136630
New sources of pancreatic beta-cellsQ36186494
Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.Q36417432
Reversal of diabetes by pancreatic islet transplantation into a subcutaneous, neovascularized deviceQ38453175
Insulin independence after living-donor distal pancreatectomy and islet allotransplantationQ40423359
Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugsQ40436881
Silymarin protects pancreatic beta-cells against cytokine-mediated toxicity: implication of c-Jun NH2-terminal kinase and janus kinase/signal transducer and activator of transcription pathways.Q40508923
Variables in organ donors that affect the recovery of human islets of LangerhansQ40982542
Underutilization of pancreas donors.Q42597997
Aggressive pharmacologic donor management results in more transplanted organsQ42695418
Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 geneQ43618098
Serine-protease inhibition during islet isolation increases islet yield from human pancreases with prolonged ischemiaQ43729184
Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1.Q44102776
Simvastatin induces activation of the serine-threonine protein kinase AKT and increases survival of isolated human pancreatic isletsQ44221067
17beta-Estradiol protects isolated human pancreatic islets against proinflammatory cytokine-induced cell death: molecular mechanisms and islet functionalityQ44228647
Improved islet yields from Macaca nemestrina and marginal human pancreata after two-layer method preservation and endogenous trypsin inhibitionQ44256450
Achievement of insulin independence in three consecutive type-1 diabetic patients via pancreatic islet transplantation using islets isolated at a remote islet isolation centerQ44260931
Improved human islet isolation outcome from marginal donors following addition of oxygenated perfluorocarbon to the cold-storage solutionQ44469243
Insulin independence following isolated islet transplantation and single islet infusionsQ44471640
Pancreatic islet transplantation: the radiographic approachQ44514953
Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet beta cellsQ44517194
Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantationQ44662213
Elevated portal vein drug levels of sirolimus and tacrolimus in islet transplant recipients: local immunosuppression or islet toxicity?Q44711155
Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets.Q44728965
Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibodyQ44763448
Influence of pancreas preservation on human islet isolation outcomes: impact of the two-layer methodQ44981282
Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donorsQ45010690
Improvement in islet yield from obese donors for human islet transplantsQ45072975
Refinement of the automated method for human islet isolation and presentation of a closed system for in vitro islet cultureQ45153742
Alterations of the female reproductive system in recipients of islet graftsQ45183364
Rescue purification maximizes the use of human islet preparations for transplantationQ45214551
The portal immunosuppressive storm: relevance to islet transplantation?Q45234964
Single-donor, marginal-dose islet transplantation in patients with type 1 diabetesQ45267369
Cytoprotection of pancreatic islets before and early after transplantation using gene therapyQ45883293
Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experienceQ46582092
Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs best medical therapy in type 1 diabetes mellitusQ46652782
Quality of life after islet transplantationQ46903634
Integrin signaling via RGD peptides and anti-beta1 antibodies confers resistance to apoptosis in islets of LangerhansQ46917034
Modified two-layer preservation method (M-Kyoto/PFC) improves islet yields in islet isolation.Q46936583
Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primatesQ46954587
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathwaysQ46963324
Inhibition of p38 pathway suppresses human islet production of pro-inflammatory cytokines and improves islet graft function.Q47622122
The use of non-heart-beating donors for isolated pancreatic islet transplantationQ48287728
Multi-lot analysis of custom collagenase enzyme blend in human islet isolationsQ48690351
Health-related quality of life after pancreatic islet transplantation: a longitudinal study.Q50964521
Logistics and transplant coordination activity in the GRAGIL Swiss-French multicenter network of islet transplantation.Q53273721
A functional CD40 receptor is expressed in pancreatic beta cells.Q54682415
P407language of work or nameEnglishQ1860
P304page(s)383-398
P577publication date2006-10-01
P1433published inAnnals of the New York Academy of SciencesQ2431664
P1476titleOvercoming the challenges now limiting islet transplantation: a sequential, integrated approach
P478volume1079

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cites work (P2860)
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Q41968550Automated, high-throughput assays for evaluation of human pancreatic islet function
Q84557008Blockade of leukocyte function antigen-1 (LFA-1) in clinical islet transplantation
Q91992991Direct differentiation of insulin-producing cells from human urine-derived stem cells
Q45958462Effects of pancreas cold ischemia on islet function and quality.
Q46105824Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device
Q37422976Embryonic stem cell transplantation correlates with endogenous neurogenin 3 expression and pancreas regeneration in streptozotocin-injured mice
Q34592604Glutathione ethyl ester supplementation during pancreatic islet isolation improves viability and transplant outcomes in a murine marginal islet mass model
Q37260577Hepatic hematoma after islet cell transplantation
Q37149186Human pancreatic islets and diabetes research
Q42161674In vivo imaging of vesicular monoamine transporter 2 in pancreas using an (18)F epoxide derivative of tetrabenazine
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Q42716769Islet grafting and imaging in a bioengineered intramuscular space
Q43155444Isolation of viable porcine islets by selective osmotic shock without enzymatic digestion
Q34340690Mesenchymal stem cells as feeder cells for pancreatic islet transplants
Q42555736Point: steady progress and current challenges in clinical islet transplantation
Q37377813Proangiogenic hydrogels within macroporous scaffolds enhance islet engraftment in an extrahepatic site
Q33548278Prolactin supplementation to culture medium improves beta-cell survival.
Q46468023Quantifying Insulin Therapy Requirements to Preserve Islet Graft Function Following Islet Transplantation
Q46676115Rapamycin impairs beta-cell proliferation in vivo.
Q47418206Red Ginseng Administration Before Islet Isolation Attenuates Apoptosis and Improves Islet Function and Transplant Outcome in a Syngeneic Mouse Marginal Islet Mass Model
Q46421012Riboflavin inhibits IL-6 expression and p38 activation in islet cells
Q35857021Self-assembling glucagon-like peptide 1-mimetic peptide amphiphiles for enhanced activity and proliferation of insulin-secreting cells
Q42371850Sericin in the isolating solution improves the yield of islets isolated from the pancreas
Q58579100Tetrahydrocurcumin Enhances Islet Cell Function and Attenuates Apoptosis in Mouse Islets
Q46969462Toward maximizing the success rates of human islet isolation: influence of donor and isolation factors
Q33357060Transdisciplinary approach to restore pancreatic islet function.

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