Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients.

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Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients. is …
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scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2013-12-546309
P8608Fatcat IDrelease_ag7rh6ryuffkjemsfakifkrocm
P932PMC publication ID4199956
P698PubMed publication ID25171927
P5875ResearchGate publication ID267755837

P50authorManuel R. TeixeiraQ41584388
Noel De MirandaQ42825686
Apostolos ZaravinosQ56419727
Susana LisboaQ58285812
Qiang Pan-HammarströmQ67470492
Gunilla EnbladQ89897301
P2093author name stringYixin Zeng
Longyun Chen
Zhibo Gao
Chenglin Wu
Roujun Peng
Konstantinos Georgiou
P2860cites workHuman deltex is a conserved regulator of Notch signallingQ24317290
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencingQ24612248
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphomaQ24613755
Frequent mutation of histone-modifying genes in non-Hodgkin lymphomaQ24630610
Fast and accurate short read alignment with Burrows-Wheeler transformQ24653853
Jalview Version 2--a multiple sequence alignment editor and analysis workbenchQ24655519
Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphomaQ24676965
Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiationQ24678677
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphomaQ27824784
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center originQ27851546
Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineageQ28201770
Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarrayQ28204313
Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomasQ28207345
Integrative Genomics Viewer (IGV): high-performance genomics data visualization and explorationQ28264933
Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytesQ28271869
Global epidemiology of hepatitis B virusQ28298592
Oncogenically active MYD88 mutations in human lymphomaQ28301648
Discovery and saturation analysis of cancer genes across 21 tumour typesQ28305204
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulationQ28584704
Inactivating mutations of acetyltransferase genes in B-cell lymphomaQ29031276
Diverse somatic mutation patterns and pathway alterations in human cancersQ29619825
Diffuse large B-cell lymphoma--more than a diffuse collection of large B cells: an entity in search of a meaningful classificationQ33488667
Germline Variation Controls the Architecture of Somatic Alterations in TumorsQ33707388
Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell toleranceQ33732451
Aberrant expression and reverse signalling of CD70 on malignant B cellsQ33872027
SNP detection for massively parallel whole-genome resequencingQ34017409
VarScan: variant detection in massively parallel sequencing of individual and pooled samplesQ34018143
Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1.Q34116313
Analysis of the coding genome of diffuse large B-cell lymphomaQ34205133
Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.Q34277639
Primer-BLAST: a tool to design target-specific primers for polymerase chain reactionQ34307627
Agonist anti-human CD27 monoclonal antibody induces T cell activation and tumor immunity in human CD27-transgenic miceQ34370354
Mechanisms of chromosomal translocations in B cell lymphomasQ34405423
Deltex-1 activates mitotic signaling and proliferation and increases the clonogenic and invasive potential of U373 and LN18 glioblastoma cells and correlates with patient survivalQ34603835
The double-edged sword of Notch signaling in cancerQ35989577
The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone developmentQ36193517
Genetic heterogeneity of diffuse large B-cell lymphomaQ36567845
Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphomaQ36629205
Recurrent targets of aberrant somatic hypermutation in lymphomaQ37030889
Germinal centres: role in B-cell physiology and malignancyQ37039584
High-resolution mapping of copy-number alterations with massively parallel sequencingQ37072451
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencingQ37098851
DNA repair genes are selectively mutated in diffuse large B cell lymphomasQ37125781
Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndromeQ37246532
Multiple roles of Lyn kinase in myeloid cell signaling and functionQ37416257
Correlating notch signaling with thymocyte maturationQ37462948
Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathologyQ37474941
Targeting pathological B cell receptor signalling in lymphoid malignanciesQ38085501
Regulation of innate and adaptive immunity by NotchQ38105858
Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomasQ39418718
Combined genetic inactivation of β2-Microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphomaQ39433857
Oncogenic CARD11 mutations in human diffuse large B cell lymphomaQ40005246
The GCB subtype of diffuse large B-cell lymphoma is less frequent in Asian countriesQ40221294
Differences in the cytogenetic alteration profiles of diffuse large B-cell lymphoma among Chinese and American patientsQ45391275
AID is required for germinal center-derived lymphomagenesisQ46861217
The costimulatory molecule CD70 is regulated by distinct molecular mechanisms and is associated with overall survival in diffuse large B-cell lymphoma.Q50953796
Helicobacter pylori antibodies in relation to precancerous gastric lesions in a high-risk Chinese population.Q51007392
National survey of drug-resistant tuberculosis in ChinaQ64125840
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)2544-2553
P577publication date2014-08-29
P1433published inBloodQ885070
P1476titleExome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients
P478volume124

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cites work (P2860)
Q48158448A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets.
Q35129157Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells
Q38959472Advances in the molecular diagnosis of diffuse large B-cell lymphoma in the era of precision medicine
Q58742871B cells with aberrant activation of Notch1 signaling promote Treg and Th2 cell-dominant T-cell responses via IL-33
Q33809728B-cell Function Gene Mutations in Diffuse Large B-cell Lymphoma: A Retrospective Cohort Study
Q102142158Clinical Significance of Down-Regulated CD70 and CD27 Expression in Poor Prognosis of Esophageal Squamous Cell Carcinoma
Q88084601Clinical and functional impact of recurrent S1PR1 mutations in mantle cell lymphoma
Q27027493Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond
Q37549738Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency
Q26776038Cracking the Code of Human Diseases Using Next-Generation Sequencing: Applications, Challenges, and Perspectives
Q92022489De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways
Q42336333Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma
Q38372504Flow cytometric sorting coupled with exon capture sequencing identifies somatic mutations in archival lymphoma tissues
Q98281008Genetic heterogeneity and prognostic impact of recurrent ANK2 and TP53 mutations in mantle cell lymphoma: a multi-centre cohort study
Q38739035Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations.
Q38669131Genetic landscape and deregulated pathways in B-cell lymphoid malignancies
Q52653323Genetic landscape of hepatitis B virus-associated diffuse large B-cell lymphoma.
Q95940670Genome-defined African ancestry is associated with distinct mutations and worse survival in patients with diffuse large B-Cell lymphoma
Q57059909Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma
Q91737485Genomic Alterations In Primary Cardiac Diffuse Large B Cell Lymphoma: A Case Report And Literature Review
Q88654101Genomic landscape and prognostic analysis of mantle cell lymphoma
Q38364884Germinal centres and B cell lymphomagenesis
Q38756189Germline mutations predisposing to diffuse large B-cell lymphoma.
Q60921239Identification of recurrent noncoding mutations in B-cell lymphoma using capture Hi-C
Q37549726Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection
Q51259501Molecular Pathogenesis of Diffuse Large B-Cell Lymphoma.
Q92052628Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling
Q57909099Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
Q59791012Mutational Evolution in Relapsed Diffuse Large B-Cell Lymphoma
Q94571342Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
Q27304386Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review
Q35672428Revealing Genomic Profile That Underlies Tropism of Myeloma Cells Using Whole Exome Sequencing
Q42377155Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes
Q47709959Single-agent ibrutinib in relapsed or refractory follicular lymphoma: a phase 2 consortium trial.
Q58088024TIRAP p.R81C is a novel lymphoma risk variant which enhances cell proliferation via NF-κB mediated signaling in B-cells
Q57475962Targeted next generation sequencing reveals high mutation frequency of , and in high-grade B-cell lymphoma with and and /or rearrangements
Q90428426Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report
Q64092509Transmission of diffuse large B-cell lymphoma by an allogeneic stem-cell transplant
Q62490013Unraveling transformation of follicular lymphoma to diffuse large B-cell lymphoma
Q61053563Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B-cell lymphoma
Q33701845Whole-exome analysis reveals novel somatic genomic alterations associated with cell of origin in diffuse large B-cell lymphoma
Q36392470Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution

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