scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1025821430 |
P356 | DOI | 10.1038/363449A0 |
P698 | PubMed publication ID | 8389005 |
P50 | author | Richard ffrench-Constant | Q41847859 |
P2093 | author name string | Rocheleau TA | |
Chalmers AE | |||
Steichen JC | |||
P2860 | cites work | Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology | Q24306621 |
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina | Q24314636 | ||
Novel GABA responses from rod-driven retinal horizontal cells | Q28265347 | ||
GABAergic mechanisms in the pathogenesis and treatment of epilepsy | Q28271123 | ||
Pharmacology of GABA receptor CI− channels in rat retinal bipolar cells | Q28297635 | ||
Gene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.) | Q28333319 | ||
Two novel GABAA receptor subunits exist in distinct neuronal subpopulations | Q28565909 | ||
Mechanism of gamma aminobutyric acid (GABA) action and its relation to synaptic inhibition | Q34245114 | ||
Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence | Q34707676 | ||
Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate gamma-aminobutyric acid subtype A receptor locus. | Q37579965 | ||
Molecular biology of GABAA receptors | Q37873245 | ||
Receptors for gamma-aminobutyric acid and voltage-dependent chloride channels as targets for drugs and toxicants | Q38179155 | ||
Ecological genetics of insecticide and acaricide resistance | Q39757167 | ||
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance | Q43509560 | ||
Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor | Q43866558 | ||
Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family | Q48341437 | ||
Drosophila cyclodiene resistance gene shows conserved genomic organization with vertebrate gamma-aminobutyric acidA receptors. | Q52441406 | ||
Isolation of dieldrin resistance from field populations of Drosophila melanogaster (Diptera: Drosophilidae). | Q52449251 | ||
Monogenic inheritance of cyclodiene insecticide resistance in mosquitofish, Gambusia affinis. | Q52464853 | ||
PERIPHERAL INHIBITION IN SKELETAL MUSCLE OF INSECTS | Q52637903 | ||
Single subunits of the GABAA receptor form ion channels with properties of the native receptor | Q69839770 | ||
P433 | issue | 6428 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | insecticide | Q181322 |
Drosophila | Q312154 | ||
insecticide resistance | Q60036895 | ||
P304 | page(s) | 449-451 | |
P577 | publication date | 1993-06-01 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | A point mutation in a Drosophila GABA receptor confers insecticide resistance | |
P478 | volume | 363 |
Q44478388 | A case of accidental ingestion of ant bait containing fipronil |
Q49023322 | A functional comparison of the antagonists bicuculline and picrotoxin at recombinant GABAA receptors |
Q40740515 | A glutamate-gated chloride channel subunit from Haemonchus contortus: expression in a mammalian cell line, ligand binding, and modulation of anthelmintic binding by glutamate |
Q50644841 | A nicotinic acetylcholine receptor mutation (Y151S) causes reduced agonist potency to a range of neonicotinoid insecticides. |
Q33853977 | A nicotinic acetylcholine receptor mutation conferring target-site resistance to imidacloprid in Nilaparvata lugens (brown planthopper). |
Q48111061 | A novel invertebrate GABAA receptor-like polypeptide. Sequence and pattern of gene expression. |
Q71981092 | A novel γ-aminobutyric acid response in the embryonic brainstem as revealed by voltage-sensitive dye recording |
Q35237427 | A pentasymmetric open channel blocker for Cys-loop receptor channels |
Q46658255 | A picrotoxin-specific conformational change in the glycine receptor M2-M3 loop |
Q35913041 | A single amino acid determines the toxicity of Ginkgo biloba extracts |
Q33720641 | A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition |
Q31962028 | A single beta subunit M2 domain residue controls the picrotoxin sensitivity of alphabeta heteromeric glycine receptor chloride channels |
Q28367616 | A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms |
Q48019584 | Acetylcholinesterase cDNA of the cattle tick, Boophilus microplus: characterisation and role in organophosphate resistance |
Q35167827 | Actions of agonists, fipronil and ivermectin on the predominant in vivo splice and edit variant (RDLbd, I/V) of the Drosophila GABA receptor expressed in Xenopus laevis oocytes |
Q42282924 | Actions of picrodendrin antagonists on dieldrin-sensitive and -resistant Drosophila GABA receptors |
Q49057411 | Actions of picrotoxinin analogues on an expressed, homo-oligorneric GABA receptor receptor of Drosophila melanogaster |
Q42708156 | Actions of the insecticide fipronil, on dieldrin‐sensitive and ‐resistant GABA receptors of Drosophila melanogaster |
Q44561645 | Activation-dependent properties of pregnenolone sulfate inhibition of GABAA receptor-mediated current |
Q41983842 | Agonist pharmacology of two Drosophila GABA receptor splice variants |
Q34171694 | Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine |
Q41881591 | Allosteric modulation of an expressed homo-oligomeric GABA-gated chloride channel of Drosophila melanogaster |
Q44540562 | Altered ivermectin pharmacology and defective visual system in Drosophila mutants for histamine receptor HCLB. |
Q48041434 | Alternative splicing of a Caenorhabditis elegans gene produces two novel inhibitory amino acid receptor subunits with identical ligand binding domains but different ion channels |
Q31875249 | Alternative splicing of a Drosophila GABA receptor subunit gene identifies determinants of agonist potency |
Q49130656 | Amino acids lining the channel of the gamma-aminobutyric acid type A receptor identified by cysteine substitution |
Q50761247 | An amino acid substitution in the pore region of a glutamate-gated chloride channel enables the coupling of ligand binding to channel gating. |
Q42550057 | An atypical residue in the pore of Varroa destructor GABA-activated RDL receptors affects picrotoxin block and thymol modulation |
Q48663996 | Analysis of γ-aminobutyric acid (GABA) type A receptor subtypes using isosteric and allosteric ligands |
Q33537038 | Anthelmintic resistance: past, present and future |
Q48529524 | BIDN, a bicyclic dinitrile convulsant, selectively blocks GABA-gated Cl- channels |
Q35080454 | Binding sites for bilobalide, diltiazem, ginkgolide, and picrotoxinin at the 5-HT3 receptor |
Q44169491 | Blood meal acquisition enhances arbovirus replication in mosquitoes through activation of the GABAergic system |
Q44010661 | Ca2+/calmodulin-dependent protein kinase regulates GABA-activated Cl- current in cockroach dorsal unpaired median neurons |
Q34170968 | Cation permeability and cation-anion interactions in a mutant GABA-gated chloride channel from Drosophila. |
Q47112786 | Changes in Neuronal Signaling and Cell Stress Response Pathways are Associated with a Multigenic Response of Drosophila melanogaster to DDT Selection |
Q49029047 | Channel gating in the absence of agonist by a homo-oligomeric molluscan GABA receptor expressed in Xenopus oocytes from a cloned cDNA. |
Q27303087 | Chaoborus and gasterosteus anti-predator responses in Daphnia pulex are mediated by independent cholinergic and gabaergic neuronal signals |
Q30672582 | Characterization and comparative pharmacological studies of a functional gamma-aminobutyric acid (GABA) receptor cloned from the tobacco budworm, Heliothis virescens (Noctuidae:Lepidoptera). |
Q35047191 | Chronic NGF treatment of rat nociceptive DRG neurons in culture facilitates desensitization and deactivation of GABAA receptor-mediated currents |
Q56927689 | Cloning and Functional Characterisation of the Duplicated RDL Subunits from the Pea Aphid, |
Q35551031 | Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor |
Q28579329 | Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block |
Q52746047 | Concentration-dependent effects of GABA on insensitivity to fipronil in the A2'S mutant RDL GABA receptor from fipronil-resistant Oulema oryzae (Coleoptera: Chrysomelidae). |
Q100738800 | Conditional protein tagging methods reveal highly specific subcellular distribution of ion channels in motion-sensing neurons |
Q38558791 | Conservation of cyclodiene insecticide resistance-associated mutations in insects. |
Q37366065 | Constitutive activation of the Nrf2/Keap1 pathway in insecticide-resistant strains of Drosophila |
Q43038629 | Cross-resistance with dieldrin of a novel tricyclic dinitrile GABA receptor antagonist |
Q28369450 | Cyanotriphenylborate: subtype-specific blocker of glycine receptor chloride channels |
Q39949261 | Cys-loop receptor channel blockers also block GLIC. |
Q43562393 | Cysteine mutants as chemical sensors for ligand-receptor interactions |
Q36322498 | DIRProt: a computational approach for discriminating insecticide resistant proteins from non-resistant proteins. |
Q40665718 | Detection of point mutations by solid-phase methods. |
Q44170359 | Dieldrin resistance in the malaria vector Anopheles gambiae in Ghana. |
Q36872171 | Differential actions of insecticides on target sites: basis for selective toxicity |
Q34408028 | Differential mechanisms of action of the novel γ-aminobutyric acid receptor antagonist ectoparasiticides fluralaner (A1443) and fipronil |
Q52606854 | Differential sensitivity of two insect GABA-gated chloride channels to dieldrin, fipronil and picrotoxinin. |
Q38089188 | Discriminating between 5-HT₃A and 5-HT₃AB receptors |
Q48921734 | Distribution of two GABA receptor-like subunits in the Drosophila CNS. |
Q30504137 | Divergence of larval morphology between Drosophila sechellia and its sibling species caused by cis-regulatory evolution of ovo/shaven-baby |
Q34749269 | Drug interactions at GABA(A) receptors |
Q35582101 | Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. |
Q44174460 | Duplication of the Ace.1 locus in Culex pipiens mosquitoes from the Caribbean |
Q42658321 | Effect of substituting amino acids in extracellular disulfide loop on GABA rho1 subunit function |
Q28379082 | Effects of [3H]-BIDN, a novel bicyclic dinitrile radioligand for GABA-gated chloride channels of insects and vertebrates |
Q46894131 | Efficacy of a topically applied spot-on formulation of a novel insecticide, metaflumizone, applied to cats against a flea strain (KS1) with documented reduced susceptibility to various insecticides |
Q41365085 | Evolution and overview of classical transmitter molecules and their receptors |
Q34172053 | Existence of the rdl mutant alleles among the anopheles malaria vector in Indonesia |
Q56772976 | Experimental evidence for pseudo-arrhenotoky in Hypothenemus hampei (Coleoptera: Scolytidae) |
Q48251848 | Expression of Cys-loop receptor subunits and acetylcholine binding protein in the mechanosensory neurons, glial cells, and muscle tissue of the spider Cupiennius salei |
Q41509312 | Expression of a Drosophila GABA receptor in a baculovirus insect cell system. Functional expression of insecticide susceptible and resistant GABA receptors from the cyclodiene resistance gene Rdl. |
Q44668832 | Fipronil modulation of glutamate-induced chloride currents in cockroach thoracic ganglion neurons |
Q43777264 | Fipronil-based photoaffinity probe for Drosophila and human beta 3 GABA receptors |
Q37594673 | Frequency of hybridization between Ostrinia nubilalis E-and Z-pheromone races in regions of sympatry within the United States |
Q42006694 | Functional analysis of a point mutation in the ryanodine receptor of Plutella xylostella (L.) associated with resistance to chlorantraniliprole |
Q50640704 | Functional characterization of Musca glutamate- and GABA-gated chloride channels expressed independently and coexpressed in Xenopus oocytes. |
Q42938379 | Functional consequences of mutations in the Drosophila histamine receptor HCLB. |
Q40453946 | Functional domains of GABAA receptors. |
Q40694885 | Functional expression of insecticide-resistant GABA receptors from the mosquito Aedes aegypti. |
Q33875295 | Functional haplodiploidy: a mechanism for the spread of insecticide resistance in an important international insect pest |
Q44477223 | GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons. |
Q42275478 | GABAA receptor open-state conformation determines non-competitive antagonist binding |
Q34365717 | GABAA receptor structure-function studies: a reexamination in light of new acetylcholine receptor structures |
Q50178492 | GABAA receptor: Positive and negative allosteric modulators |
Q35964827 | GABAC receptor ion channels |
Q28294406 | GABAC receptors in the vertebrate retina |
Q28360170 | GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans |
Q46101138 | Gamma-aminobutyric acid (GABA)-mediated neural connections in the Drosophila antennal lobe |
Q37157277 | Gene duplication in the major insecticide target site, Rdl, in Drosophila melanogaster |
Q52552329 | Genetic approaches to CNS disorders with particular reference to GABAA-receptor mutations. |
Q37109232 | Genetic basis of fitness differences in natural populations |
Q37432730 | Genetic variation, inbreeding and chemical exposure--combined effects in wildlife and critical considerations for ecotoxicology |
Q52583009 | Genetics of alpha-amanitin resistance in a natural population of Drosophila melanogaster. |
Q42703056 | Genomics of parallel adaptation at two timescales in Drosophila |
Q44472932 | Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin |
Q41707937 | Heritable mutations in the glycine, GABAA, and nicotinic acetylcholine receptors provide new insights into the ligand-gated ion channel receptor superfamily. |
Q43244132 | Homomeric RDL and heteromeric RDL/LCCH3 GABA receptors in the honeybee antennal lobes: two candidates for inhibitory transmission in olfactory processing |
Q36628553 | Identification and distribution of a GABA receptor mutation conferring dieldrin resistance in the malaria vector Anopheles funestus in Africa. |
Q43823925 | Identification of a novel residue within the second transmembrane domain that confers use-facilitated block by picrotoxin in glycine alpha 1 receptors. |
Q36415753 | Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit |
Q48060948 | Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides |
Q54797307 | Immunocytochemical localization of putative gamma-aminobutyric acid receptor subunits in the head ganglia of Periplaneta americana using an anti-RDL C-terminal antibody. |
Q48179268 | Immunocytochemistry of GABA in the central complex of the locust Schistocerca gregaria: identification of immunoreactive neurons and colocalization with neuropeptides |
Q52560091 | Immunocytochemistry of a novel GABA receptor subunit Rdl in Drosophila melanogaster. |
Q90636580 | In Silico Site-Directed Mutagenesis Informs Species-Specific Predictions of Chemical Susceptibility Derived From the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) Tool |
Q40893586 | Influence of subunit configuration on the interaction of picrotoxin-site ligands with recombinant GABA(A) receptors |
Q32178009 | Insecticide resistance and resistance mechanisms in bed bugs, Cimex spp. (Hemiptera: Cimicidae). |
Q48158505 | Interaction of anisatin with rat brain gamma-aminobutyric acidA receptors: allosteric modulation by competitive antagonists |
Q48910191 | Interaction of non-competitive blockers within the gamma-aminobutyric acid type A chloride channel using chemically reactive probes as chemical sensors for cysteine mutants |
Q34047528 | Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants. |
Q41991553 | Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes. |
Q33900762 | Ion channels and synaptic organization: analysis of the Drosophila genome |
Q38996100 | Ion channels as insecticide targets. |
Q36261790 | Ion channels: molecular targets of neuroactive insecticides |
Q47953704 | Isolation of a cDNA for an octopamine-like, G-protein coupled receptor from the cattle tick, Boophilus microplus |
Q38687540 | Isoxazolines: A Novel Chemotype Highly Effective on Ectoparasites |
Q33746750 | Ivermectin sensitivity is an ancient trait affecting all ecdysozoa but shows phylogenetic clustering among sepsid flies |
Q35924807 | Mapping convulsants' binding to the GABA-A receptor chloride ionophore: a proposed model for channel binding sites |
Q35527645 | Meroterpenoid Chrodrimanins Are Selective and Potent Blockers of Insect GABA-Gated Chloride Channels |
Q27682601 | Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae |
Q36301309 | Mixed antagonistic effects of the ginkgolides at recombinant human ρ1 GABAC receptors |
Q51088379 | Modeling the interaction of fipronil-related non-competitive antagonists with the GABA beta3-receptor. |
Q36404799 | Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop |
Q37127456 | Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila |
Q35026741 | Modulation of a recombinant invertebrate gamma-aminobutyric acid receptor-chloride channel complex by isoflurane: effects of a point mutation in the M2 domain |
Q39195968 | Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels |
Q41365159 | Molecular biology and electrophysiology of glutamate-gated chloride channels of invertebrates |
Q41673439 | Molecular biology of insect neuronal GABA receptors |
Q35844251 | Molecular cloning and expression of a GABA receptor subunit from the crayfish Procambarus clarkii |
Q57838239 | Molecular determinants of ginkgolide binding in the glycine receptor pore |
Q43850140 | Morphological and electrophysiological evidence for an ionotropic GABA receptor of novel pharmacology |
Q46606906 | Multiple Mutations on the Second Acetylcholinesterase Gene Associated With Dimethoate Resistance in the Melon Aphid, Aphis gossypii (Hemiptera: Aphididae). |
Q58544853 | Multiple combinations of RDL subunits diversify the repertoire of GABA receptors in the honeybee parasite |
Q34534563 | Multiple origins of kdr-type resistance in the house fly, Musca domestica. |
Q36869430 | Nematode ligand-gated chloride channels: an appraisal of their involvement in macrocyclic lactone resistance and prospects for developing molecular markers |
Q43783019 | Neuroactive steroids modulate crustacean locomotor activity |
Q41067054 | Neurosteroid modulation of native and recombinant GABAA receptors. |
Q34429095 | Non-competitive GABA antagonists: probing the mechanisms of their selectivity for insect versus mammalian receptors |
Q43508119 | Noncompetitive antagonist-binding sites of rat and housefly gamma-aminobutyric acid receptors display different enantiospecificities for tert-butyl(isopropyl)bicyclophosphorothionate |
Q34742130 | Novel animal-health drug targets from ligand-gated chloride channels. |
Q83227438 | ON selectivity in the visual system is a multisynaptic process involving both glutamatergic and GABAergic inhibition |
Q36332592 | Orientation Selectivity Sharpens Motion Detection in Drosophila |
Q41065249 | Pharmacological and physiological characterization of murine homomeric beta3 GABA(A) receptors |
Q48661788 | Pharmacological characterization of the Haemonchus contortus GABA-gated chloride channel, Hco-UNC-49: modulation by macrocyclic lactone anthelmintics and a receptor for piperazine |
Q35045055 | Pharmacological characterization of the homomeric and heteromeric UNC-49 GABA receptors in C. elegans |
Q39467699 | Picrodendrin and related terpenoid antagonists reveal structural differences between ionotropic GABA receptors of mammals and insects |
Q47778405 | Pleiotropic Effects of Loss of the Dα1 Subunit in Drosophila melanogaster: Implications for Insecticide Resistance |
Q38549527 | Polycyclic dinitriles: a novel class of potent GABAergic insecticides provides a new radioligand, [3H]BIDN. |
Q43049138 | Polymerase chain reaction diagnostic for cyclodiene insecticide resistance in the mosquito Aedes aegypti |
Q42723261 | Polymorphism in the acetylcholinesterase gene of Musca domestica L. field populations in Turkey |
Q98891602 | Post-transcriptional modulation of cytochrome P450s, Cyp6g1 and Cyp6g2, by miR-310s cluster is associated with DDT-resistant Drosophila melanogaster strain 91-R |
Q34554306 | Pre-invasion history and demography shape the genetic variation in the insecticide resistance-related acetylcholinesterase 2 gene in the invasive Colorado potato beetle |
Q28363363 | Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunit |
Q28239408 | Principles of agonist recognition in Cys-loop receptors |
Q34528520 | Putative excitatory and putative inhibitory inputs are localised in different dendritic domains in a Drosophila flight motoneuron |
Q35116397 | Quantification of the pirimicarb resistance allele frequency in pooled cotton aphid (Aphis gossypii Glover) samples by TaqMan SNP genotyping assay |
Q92666238 | RDL mutations in Guangxi Anopheles sinensis populations along the China-Vietnam border: distribution frequency and evolutionary origin of A296S resistance allele |
Q54746106 | Rapid detection of chicken and turkey in heated meat products using the polymerase chain reaction followed by amplicon visualisation with vistra green. |
Q44456016 | RdlDv, a novel GABA-gated chloride channel gene from the American dog tick Dermacentor variabilis |
Q37800821 | Recent progress in understanding the interaction between avermectins and ligand-gated ion channels: putting the pests to sleep |
Q42700989 | Reduction in mRNA and protein expression of a nicotinic acetylcholine receptor α8 subunit is associated with resistance to imidacloprid in the brown planthopper, Nilaparvata lugens |
Q50648266 | Replacement of asparagine with arginine at the extracellular end of the second transmembrane (M2) region of insect GABA receptors increases sensitivity to penicillin G. |
Q35100863 | Residues in the first transmembrane domain of the Caenorhabditis elegans GABA(A) receptor confer sensitivity to the neurosteroid pregnenolone sulfate |
Q28369230 | Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase |
Q37197112 | Reticulate Speciation and Barriers to Introgression in the Anopheles gambiae Species Complex |
Q44754921 | Role of a γ-aminobutryic acid (GABA) receptor mutation in the evolution and spread of Diabrotica virgifera virgifera resistance to cyclodiene insecticides |
Q44597814 | Selection at a γ-aminobutyric acid receptor gene in Haemonchus contortus resistant to avermectins/milbemycins |
Q52542732 | Selection at the diazinon resistance locus in overwintering populations of Lucilia cuprina (the Australian sheep blowfly). |
Q56994473 | Side-chain control of porosity closure in single- and multiple-peptide-based porous materials by cooperative folding |
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Q42043035 | Single amino acid mutations in the cadherin receptor from Heliothis virescens affect its toxin binding ability to Cry1A toxins |
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Q38563956 | Single-stranded DNA conformation polymorphism at the Rdl locus in Hypothenemus hampei (Coleoptera: Scolytidae). |
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Q37203454 | Synergistic and compensatory effects of two point mutations conferring target-site resistance to fipronil in the insect GABA receptor RDL. |
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