A point mutation in a Drosophila GABA receptor confers insecticide resistance.

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A point mutation in a Drosophila GABA receptor confers insecticide resistance. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1025821430
P356DOI10.1038/363449A0
P698PubMed publication ID8389005

P50authorRichard ffrench-ConstantQ41847859
P2093author name stringRocheleau TA
Chalmers AE
Steichen JC
P2860cites workImportance of a novel GABAA receptor subunit for benzodiazepine pharmacologyQ24306621
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retinaQ24314636
Novel GABA responses from rod-driven retinal horizontal cellsQ28265347
GABAergic mechanisms in the pathogenesis and treatment of epilepsyQ28271123
Pharmacology of GABA receptor CI− channels in rat retinal bipolar cellsQ28297635
Gene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.)Q28333319
Two novel GABAA receptor subunits exist in distinct neuronal subpopulationsQ28565909
Mechanism of gamma aminobutyric acid (GABA) action and its relation to synaptic inhibitionQ34245114
Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequenceQ34707676
Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate gamma-aminobutyric acid subtype A receptor locus.Q37579965
Molecular biology of GABAA receptorsQ37873245
Receptors for gamma-aminobutyric acid and voltage-dependent chloride channels as targets for drugs and toxicantsQ38179155
Ecological genetics of insecticide and acaricide resistanceQ39757167
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductanceQ43509560
Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptorQ43866558
Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-familyQ48341437
Drosophila cyclodiene resistance gene shows conserved genomic organization with vertebrate gamma-aminobutyric acidA receptors.Q52441406
Isolation of dieldrin resistance from field populations of Drosophila melanogaster (Diptera: Drosophilidae).Q52449251
Monogenic inheritance of cyclodiene insecticide resistance in mosquitofish, Gambusia affinis.Q52464853
PERIPHERAL INHIBITION IN SKELETAL MUSCLE OF INSECTSQ52637903
Single subunits of the GABAA receptor form ion channels with properties of the native receptorQ69839770
P433issue6428
P407language of work or nameEnglishQ1860
P921main subjectinsecticideQ181322
DrosophilaQ312154
insecticide resistanceQ60036895
P304page(s)449-451
P577publication date1993-06-01
P1433published inNatureQ180445
P1476titleA point mutation in a Drosophila GABA receptor confers insecticide resistance
P478volume363

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Q43511697Two novel residues in M2 of the gamma-aminobutyric acid type A receptor affecting gating by GABA and picrotoxin affinity.
Q47102260Using Next-Generation Sequencing to Detect Differential Expression Genes in Bradysia odoriphaga after Exposure to Insecticides
Q33533886Why are there so few resistance-associated mutations in insecticide target genes?
Q41243338Wild-type and insecticide-resistant homo-oligomeric GABA receptors of Drosophila melanogaster stably expressed in a Drosophila cell line
Q40613437[3H]Ethynylbicycloorthobenzoate ([3H]EBOB) binding in recombinant GABAA receptors
Q48862251pH-dependent actions of THIP and ZAPA on an ionotropic Drosophila melanogaster GABA receptor

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