Lymphatic vessels as targets of tumor therapy?

scientific article

Lymphatic vessels as targets of tumor therapy? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.194.6.F37
P932PMC publication ID2195960
P698PubMed publication ID11561002
P5875ResearchGate publication ID11786989

P50authorKari AlitaloQ6370341
P2093author name stringT Karpanen
P2860cites workLYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronanQ22008808
Involvement of chemokine receptors in breast cancer metastasisQ24290909
Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3Q24291630
Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)Q24321792
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinasesQ24336293
Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumorsQ73254738
Increased vascular endothelial growth factor and vascular endothelial growth factor-c and decreased nm23 expression associated with microdissemination in the lymph nodes in stage I non-small cell lung cancerQ73585510
The lymphatic endothelium of the avian wing is of somitic originQ73603919
Expression of vascular endothelial growth factors A, B, C, and D and their relationships to lymph node status in lung adenocarcinomaQ73937580
Lack of lymphangiogenesis despite coexpression of VEGF-C and its receptor Flt-4 in uveal melanomaQ73943280
N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signallingQ74122026
Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancerQ78074820
Proteolytic processing regulates receptor specificity and activity of VEGF-CQ24532314
Openings between defective endothelial cells explain tumor vessel leakinessQ24681507
Angiogenesis in cancer and other diseasesQ27861015
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesisQ28140740
VEGF-D promotes the metastatic spread of tumor cells via the lymphaticsQ28200072
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasisQ28200101
Hyperplasia of lymphatic vessels in VEGF-C transgenic miceQ28238886
VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membraneQ28245526
Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-CQ28266440
Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endotheliumQ28506923
Targeting tumor vasculature with homing peptides from phage displayQ30979146
Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesisQ33927967
Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineagesQ34091556
Lymphangiogenesis and tumor metastasis: myth or reality?Q34215567
Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endotheliumQ34502407
Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanomaQ35746804
Vascular Endothelial Growth Factors VEGF-B and VEGF-C Are Expressed in Human TumorsQ35753219
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancerQ35786920
Expression of angiogenesis stimulators and inhibitors in human thyroid tumors and correlation with clinical pathological featuresQ35787996
Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing bloodQ35851436
VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours.Q36641154
Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissuesQ36642309
Vascular endothelial growth factor C induces angiogenesis in vivo.Q36734917
Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic miceQ39714957
Circulating endothelial precursors: mystery, reality, and promiseQ40741679
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.Q40827632
Vascular endothelial growth factor-C expression in human prostatic carcinoma and its relationship to lymph node metastasisQ42280089
Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxiaQ42800633
In fibroblasts Vegf-D expression is induced by cell-cell contact mediated by cadherin-11.Q42833515
Lack of lymphangiogenesis in human primary cutaneous melanoma. Consequences for the mechanism of lymphatic dissemination.Q42839298
Vascular endothelial growth factor-C (VEGF-C/VEGF-2) promotes angiogenesis in the setting of tissue ischemiaQ42850939
Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapyQ44240071
Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis.Q52539892
Chemotherapy targeted to tumor vasculature.Q54116633
Expression of vascular endothelial growth factor (VEGF) family members in breast cancer.Q55261166
Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growthQ56825474
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasisQ57382204
VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissuesQ57382249
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectenzymeQ8047
cancerQ12078
peptideQ172847
membrane proteinQ423042
lymphatic systemQ712604
growth factor receptorQ118226
neoplasmQ1216998
cell surface receptorQ2476074
hemic and immune systemsQ70202933
P304page(s)F37-42
P577publication date2001-09-01
2001-09-17
P13046publication type of scholarly workreview articleQ7318358
P1433published inJournal of Experimental MedicineQ3186912
P1476titleLymphatic vessels as targets of tumor therapy?
P478volume194

Reverse relations

cites work (P2860)
Q59694186Angiogenesis and melanoma
Q36305548Blood and lymph vessels in embryonic tumors
Q38839716Cellular fibronectin 1 promotes VEGF-C expression, lymphangiogenesis and lymph node metastasis associated with human oral squamous cell carcinoma
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Q34770288Lymphangiogenesis and cancer metastasis
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Q91789424Tumor-Draining Lymph Secretome En Route to the Regional Lymph Node in Breast Cancer Metastasis
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Q64064605Two Birds, One Stone: Double Hits on Tumor Growth and Lymphangiogenesis by Targeting Vascular Endothelial Growth Factor Receptor 3
Q35187933Vascular endothelial growth factors C and D and lymphangiogenesis in gastrointestinal tract malignancy.
Q80352869[Micro-metastases and non-small cell lung cancer]

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