Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities

scientific article

Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BBRC.2013.09.077
P932PMC publication ID4578723
P698PubMed publication ID24070612

P50authorIrina U. AgoulnikQ55456665
P2093author name stringCharles Packianathan
Barry P Rosen
Myles C Hodgson
Fikriye Uras
Sandra M Lopez
Ozlem Bingol-Ozakpinar
P2860cites workAck1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activationQ21142629
I-TASSER server for protein 3D structure predictionQ21284202
The lipid phosphatase activity of PTEN is critical for its tumor supressor functionQ22007981
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis toolsQ24248165
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor betaQ24310394
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTENQ24322051
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
A family of putative tumor suppressors is structurally and functionally conserved in humans and yeastQ24336385
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane associationQ27620298
Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factorQ28115391
Invadopodia: specialized cell structures for cancer invasionQ28251084
Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of action of the phosphataseQ28567492
Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humansQ28586887
Integrative genomic profiling of human prostate cancerQ29619905
Sequential signals toward podosome formation in NIH-src cells.Q30157646
A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screensQ30749973
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancersQ34153121
Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.Q34158474
INPP4B: the new kid on the PI3K blockQ34177821
Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signalingQ34212404
Activating SRC mutation in a subset of advanced human colon cancersQ34492512
Phosphoinositide signalling in cancer: beyond PI3K and PTEN.Q37736257
Role of phosphatidylinositol 4,5-bisphosphate in Ras/Rac-induced disruption of the cortactin-actomyosin II complex and malignant transformation.Q39575140
Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.Q39774233
Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activityQ40339658
A role for phospholipase C-gamma-mediated signaling in tumor cell invasionQ40931396
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cellsQ40993616
Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinaseQ42524332
Mycobacterium tuberculosis protein tyrosine phosphatase PtpB structure reveals a diverged fold and a buried active siteQ46515487
Molecular inhibition of phospholipase cgamma signaling abrogates DU-145 prostate tumor cell invasionQ77553791
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)277-282
P577publication date2013-09-23
P1433published inBiochemical and Biophysical Research CommunicationsQ864228
P1476titleDeterminants of the tumor suppressor INPP4B protein and lipid phosphatase activities
P478volume440

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cites work (P2860)
Q37005755INPP4B is an oncogenic regulator in human colon cancer.
Q49993172INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia
Q38953956INPP4B suppresses prostate cancer cell invasion
Q91519231Inositol polyphosphate 4-phosphatase type II regulation of androgen receptor activity
Q29248612Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases
Q38634867The extended human PTPome: a growing tyrosine phosphatase family

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