Minireview: Metabolic control of the reproductive physiology: insights from genetic mouse models

scientific article

Minireview: Metabolic control of the reproductive physiology: insights from genetic mouse models is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YHBEH.2014.04.007
P932PMC publication ID4204395
P698PubMed publication ID24746731

P50authorCarol F EliasQ56418721
P2093author name stringNicole Bellefontaine
P2860cites workInactivating KISS1 mutation and hypogonadotropic hypogonadismQ55671569
IRS-2 pathways integrate female reproduction and energy homeostasisQ59088199
Leptin signalingQ80123320
PI3K: An Attractive Candidate for the Central Integration of Metabolism and ReproductionQ21131282
Ghrelin is a growth-hormone-releasing acylated peptide from stomachQ22010951
Positional cloning of the mouse obese gene and its human homologueQ22251285
A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate familyQ24323752
Mice lacking ghrelin receptors resist the development of diet-induced obesityQ24536127
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertilityQ24594995
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54Q24685744
Leptin action in pubertal development: recent advances and unanswered questionsQ26996082
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptinQ28115346
The GPR54 gene as a regulator of pubertyQ28211950
Mouse fertility is not dependent on the CREB coactivator Crtc1Q28513088
Insulin receptor substrate 2 is required for testicular developmentQ28533530
Intracellular signalling. Key enzyme in leptin-induced anorexiaQ28573472
STAT3 signalling is required for leptin regulation of energy balance but not reproductionQ28589994
Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulationQ28594707
Serum immunoreactive-leptin concentrations in normal-weight and obese humansQ29617230
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjectsQ29617231
Role of leptin in the neuroendocrine response to fastingQ29618866
Ghrelin induces adiposity in rodentsQ29619226
Delayed puberty but normal fertility in mice with selective deletion of insulin receptors from Kiss1 cellsQ30414505
Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptorQ30430757
The effect of insulin signaling on female reproductive function independent of adiposity and hyperglycemiaQ30432818
Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.Q30433558
The Creb1 coactivator Crtc1 is required for energy balance and fertilityQ30439853
Estradiol modulates Kiss1 neuronal response to ghrelinQ30968618
Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neuronsQ33720343
Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.Q33872535
Effects of recombinant leptin therapy in a child with congenital leptin deficiency.Q33874084
Leptin regulation of neuroendocrine systemsQ33959604
Divergent roles of growth factors in the GnRH regulation of puberty in miceQ34028676
Leptin induces phosphorylation of neuronal nitric oxide synthase in defined hypothalamic neurons.Q34197764
Obese, a new mutation in the house mouseQ34296323
Trophic action of leptin on hypothalamic neurons that regulate feedingQ34311092
Minireview: From anorexia to obesity--the yin and yang of body weight controlQ34536426
Leptin signaling in Kiss1 neurons arises after pubertal developmentQ34626000
Molecular mapping of the neural pathways linking leptin to the neuroendocrine reproductive axisQ35001311
Ghrelin in the regulation of body weight and metabolismQ35011714
Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neuronsQ35100714
The role of leptin receptor signaling in feeding and neuroendocrine functionQ35595300
Mice lacking inhibitory leptin receptor signals are lean with normal endocrine functionQ35723381
Ablation of neurons expressing agouti-related protein, but not melanin concentrating hormone, in leptin-deficient mice restores metabolic functions and fertilityQ35779008
Transgenic rescue of insulin receptor-deficient miceQ35835529
Expression of ghrelin receptor mRNA in the rat and the mouse brainQ35915057
The ventral premammillary nucleus links metabolic cues and reproductionQ35971141
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.Q35973482
IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin actionQ35993401
Effects of leptin and melanocortin signaling interactions on pubertal development and reproductionQ36052249
Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balanceQ36493391
Leptin signaling and circuits in puberty and fertilityQ36598687
Leptin action via LepR-b Tyr1077 contributes to the control of energy balance and female reproductionQ37133393
An eGFP-expressing subpopulation of growth hormone secretagogue receptor cells are distinct from kisspeptin, tyrosine hydroxylase, and RFamide-related peptide neurons in mice.Q37146669
Direct innervation of GnRH neurons by metabolic- and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleusQ37174118
The ventral premammillary nucleus links fasting-induced changes in leptin levels and coordinated luteinizing hormone secretion.Q37226994
Leptin targets in the mouse brainQ37260766
Ghrelin as a pleotrophic modulator of gonadal function and reproductionQ37316539
Leptin indirectly regulates gonadotropin-releasing hormone neuronal functionQ37319598
Leptin accelerates the onset of puberty in normal female miceQ37362961
Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasisQ37418266
Agouti-related peptide plays a critical role in leptin's effects on female puberty and reproductionQ37439782
Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasisQ37594442
Central nervous system control of metabolism.Q38059776
Interface between metabolic balance and reproduction in ruminants: focus on the hypothalamus and pituitaryQ38191062
KiSS-1 neurones are direct targets for leptin in the ob/ob mouse.Q38315438
Expression of a leptin receptor in immortalized gonadotropin-releasing hormone-secreting neuronsQ38326594
Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat.Q38348114
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.Q38350668
Leptin signaling in GABA neurons, but not glutamate neurons, is required for reproductive functionQ39319997
From precocious puberty to infertility: metabolic control of the reproductive functionQ39492592
Distribution of estrogen receptor alpha and beta in the mouse central nervous system: in vivo autoradiographic and immunocytochemical analysesQ40515800
Insulin and IGF-I signaling through the insulin receptor substrate 1.Q40858638
Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 geneQ40968948
GABAergic RIP-Cre neurons in the arcuate nucleus selectively regulate energy expenditureQ41420919
Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertilityQ42477762
Effects of ghrelin upon gonadotropin-releasing hormone and gonadotropin secretion in adult female rats: in vivo and in vitro studiesQ42495834
The insulin-elicited 60-kDa phosphotyrosine protein in rat adipocytes is associated with phosphatidylinositol 3-kinaseQ42811072
Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgeneQ43555556
Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in ratsQ43778759
Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized ratsQ43786272
Distribution of leptin-sensitive cells in the postnatal and adult mouse brainQ43809266
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexiaQ44286336
Neither signal transducer and activator of transcription 3 (STAT3) or STAT5 signaling pathways are required for leptin's effects on fertility in miceQ44808513
Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization studyQ45020200
An allelic series for the leptin receptor gene generated by CRE and FLP recombinaseQ45076042
Leptin-dependent neuronal NO signaling in the preoptic hypothalamusfacilitates reproduction.Q45968321
Cross-talk between the insulin and leptin signaling systems in rat hypothalamus.Q46370969
Regulation of Kiss1 gene expression in the brain of the female mouse.Q46513180
The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activityQ46626373
Effects of central infusion of ghrelin on food intake and plasma levels of growth hormone, luteinizing hormone, prolactin, and cortisol secretion in sheep.Q46739952
Feedback loops link odor and pheromone signaling with reproductionQ46805992
Role of brain insulin receptor in control of body weight and reproductionQ47229086
A role for kisspeptins in the regulation of gonadotropin secretion in the mouse.Q47289867
Leptin is a metabolic gate for the onset of puberty in the female rat.Q47628007
The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate familyQ48050897
Discrete expression of insulin receptor substrate-4 mRNA in adult rat brainQ48090584
Distribution of kisspeptin neurones in the adult female mouse brainQ48577946
NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates.Q48715022
Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats.Q51480078
Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis.Q52537778
P433issue1
P304page(s)7-14
P577publication date2014-04-16
P1433published inHormones and BehaviourQ15760887
P1476titleMinireview: Metabolic control of the reproductive physiology: insights from genetic mouse models
P478volume66

Reverse relations

cites work (P2860)
Q48665210Decreased Implantation Number After In Utero Artificial Insemination Can Reflect an Impairment of Fertility in Adult Male Rats After Exogenous Leptin Exposure.
Q92463372Effects of single parenthood on mothers' behavior, morphology, and endocrine function in the biparental California mouse
Q47311516Estradiol Regulation of Brown Adipose Tissue Thermogenesis.
Q50969819Insulin Does Not Target CamkIIα Neurones to Critically Regulate the Neuroendocrine Reproductive Axis in Mice.
Q47416512Mood, Food, and Fertility: Adaptations of the Maternal Brain
Q46042235Obese Neuronal PPARγ Knockout Mice Are Leptin Sensitive but Show Impaired Glucose Tolerance and Fertility
Q90075126Obesity, Neuroinflammation, and Reproductive Function
Q33734877Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis
Q39377988The gentle art of saying NO: how nitric oxide gets things done in the hypothalamus

Search more.