Mineralocorticoid receptors in immune cells: emerging role in cardiovascular disease.

scientific article published on 21 April 2014

Mineralocorticoid receptors in immune cells: emerging role in cardiovascular disease. is …
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scholarly articleQ13442814

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P356DOI10.1016/J.STEROIDS.2014.04.005
P932PMC publication ID4205205
P698PubMed publication ID24769248

P2093author name stringHenry H Wortis
Iris Z Jaffe
Pilar Alcaide
Nicholas C Bene
P2860cites workRefining the role of B cells in atherosclerosisQ84379092
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Alternative activation of macrophagesQ27860939
Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediatedQ28281477
Mechanisms of mineralocorticoid actionQ28281657
The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study InvestigatorsQ28372091
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Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptorsQ30528005
Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunctionQ33642021
T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responsesQ33819043
Mineralocorticoid action.Q33819647
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Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathwayQ33903180
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The role of inflammatory and fibrogenic pathways in heart failure associated with aging.Q34061245
Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice.Q34090097
Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarctionQ34187441
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cellsQ34331407
T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoproteinQ34390132
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Inflammation, immunity, and hypertensionQ34528283
Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE InvestigatorsQ34539986
Myeloid-specific deletion of the mineralocorticoid receptor reduces infarct volume and alters inflammation during cerebral ischemiaQ34591546
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Expanding the effector CD4 T-cell repertoire: the Th17 lineage.Q36449975
Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cellsQ36478492
Adaptive immunity in atherogenesis: new insights and therapeutic approachesQ36497196
Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanismQ36701794
Mechanisms of cardiac fibrosis in hypertensionQ36873139
Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesionQ37003229
Regulation of T-cell function by endogenously produced angiotensin II.Q37100479
IFN-gamma potentiates atherosclerosis in ApoE knock-out miceQ37368296
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Cross-talk between aldosterone and angiotensin signaling in vascular smooth muscle cellsQ37849362
Mineralocorticoid receptors in vascular function and diseaseQ37896953
Immune modulation of resistance artery remodellingQ37899280
Protective role of natural IgM-producing B1a cells in atherosclerosisQ38030251
The immune system: role in hypertensionQ38035608
Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular diseaseQ38103479
IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activationQ38297511
Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cellsQ38330461
Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosteroneQ40559994
Systemic administration of autologous, alloactivated helper-enriched lymphocytes to patients with metastatic melanoma of the lung. A phase I study.Q40812995
Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertensionQ41956748
Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressureQ42457579
The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressureQ42468951
Pivotal role of the mineralocorticoid receptor in corticosteroid-induced adipogenesis.Q42829877
Aldosterone promotes autoimmune damage by enhancing Th17-mediated immunity.Q43233439
Effects of ramipril on coronary events in high-risk persons: results of the Heart Outcomes Prevention Evaluation StudyQ43691886
Eplerenone in patients with systolic heart failure and mild symptomsQ44272913
Effect of eplerenone, a selective aldosterone blocker, on blood pressure, serum and macrophage oxidative stress, and atherosclerosis in apolipoprotein E-deficient miceQ44459362
Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy studyQ44601096
Distinguishing the antihypertensive and electrolyte effects of eplerenoneQ44924306
IL-17 induces myocardial fibrosis and enhances RANKL/OPG and MMP/TIMP signaling in isoproterenol-induced heart failure.Q45968562
Critical role of macrophages in glucocorticoid driven vascular calcification in a mouse-model of atherosclerosisQ46372665
A Nuclear Receptor Atlas: macrophage activationQ46506122
Macrophage mineralocorticoid receptor signaling plays a key role in aldosterone-independent cardiac fibrosisQ47677228
Regulatory T cells ameliorate angiotensin II-induced cardiac damageQ47721821
Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failureQ49106538
Lentivirus mediated IL-17R blockade improves diastolic cardiac function in spontaneously hypertensive rats.Q50521732
Association between highly active antiretroviral therapy and hypertension in a large cohort of men followed from 1984 to 2003.Q50761727
Widespread Myocardial Inflammation and Infarct-Related Artery PatencyQ58230268
Local Amplification of Glucocorticoids by 11 -Hydroxysteroid Dehydrogenase Type 1 Promotes Macrophage Phagocytosis of Apoptotic LeukocytesQ61865359
Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptorQ67494059
Parallel determination of mineralocorticoid and glucocorticoid receptors in T- and B-lymphocytes of human spleenQ69833633
Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaqueQ69990504
Evidence for an increased rate of cardiovascular events in patients with primary aldosteronismQ81661632
T regulatory lymphocytes prevent aldosterone-induced vascular injuryQ82831987
T regulatory lymphocytes prevent angiotensin II-induced hypertension and vascular injuryQ83288251
Activation of CD4+ T lymphocytes improves wound healing and survival after experimental myocardial infarction in miceQ83567632
P921main subjectcardiovascular diseaseQ389735
P304page(s)38-45
P577publication date2014-04-21
P1433published inSteroidsQ15716675
P1476titleMineralocorticoid receptors in immune cells: emerging role in cardiovascular disease.
P478volume91