The melanosome: membrane dynamics in black and white

scientific article

The melanosome: membrane dynamics in black and white is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1039833483
P356DOI10.1038/35096009
P698PubMed publication ID11584301

P50authorMiguel C. SeabraQ37382816
P2093author name stringMarks MS
Seabra MC
P2860cites workThe beta3A subunit gene (Ap3b1) of the AP-3 adaptor complex is altered in the mouse hypopigmentation mutant pearl, a model for Hermansky-Pudlak syndrome and night blindnessQ22001500
Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptorQ22008778
Transfer mechanism of melanosomes in epidermal cell cultureQ67490883
Ultrastructural and cytochemical observations on B-16 and Harding-Passey mouse melanomas. The origin of premelanosomes and compound melanosomesQ68578610
Golgi-melanosome relationship in human melanoma in vitroQ69870668
Rab3a and SNARE proteins: potential regulators of melanosome movementQ73443691
The predominant defect in dilute melanocytes is in melanosome distribution and not cell shape, supporting a role for myosin V in melanosome transportQ73830033
Aberrant pH of melanosomes in pink-eyed dilution (p) mutant melanocytesQ74347101
Mouse models of Hermansky Pudlak syndrome: a reviewQ74539703
The pink-eyed dilution locus controls the biogenesis of melanosomes and levels of melanosomal proteins in the eyeQ74587768
Ocular albinism: evidence for a defect in an intracellular signal transduction systemQ22010509
Differential roles of syntaxin 7 and syntaxin 8 in endosomal traffickingQ22010801
TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomesQ24290676
Rab27a: A key to melanosome transport in human melanocytesQ24290970
PDZ domain protein GIPC interacts with the cytoplasmic tail of melanosomal membrane protein gp75 (tyrosinase-related protein-1)Q24291415
AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytesQ24291443
Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndromeQ24320302
Interaction of a Golgi-associated kinesin-like protein with Rab6Q24322499
A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3.Q24533159
Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden miceQ24555217
A millennial myosin censusQ24633678
Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cellsQ24671475
Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen miceQ24671578
Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomesQ24672025
Rab proteins as membrane organizersQ27860861
Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteinsQ27930897
The COOH-terminal domain of Myo2p, a yeast myosin V, has a direct role in secretory vesicle targetingQ27932330
Sequential action of two GTPases to promote vacuole docking and fusionQ27933688
The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosisQ27934654
Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesiclesQ27939177
Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusionQ28141271
Role of cytoplasmic dynein in melanosome transport in human melanocytesQ28142331
Colocalization of dynactin subunits P150Glued and P50 with melanosomes in normal human melanocytesQ28142439
Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13Q28142791
Role of Rab9 GTPase in facilitating receptor recruitment by TIP47Q28189682
Evolution of the Rab family of small GTP-binding proteinsQ28204091
The mouse p (pink-eyed dilution) and human P genes, oculocutaneous albinism type 2 (OCA2), and melanosomal pHQ28213415
Association of the AP-3 adaptor complex with clathrinQ28267691
Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesiclesQ28279070
Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distributionQ28505197
Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesisQ28509083
Rab27a regulates the peripheral distribution of melanosomes in melanocytesQ28513638
Novel myosin heavy chain encoded by murine dilute coat colour locusQ28590446
Mutant myosin VIIa causes defective melanosome distribution in the RPE of shaker-1 miceQ28591690
The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic proteinQ28592274
A mutation in Rab27a causes the vesicle transport defects observed in ashen miceQ28594384
Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular bodyQ29547922
Kinesin and dynein superfamily proteins and the mechanism of organelle transportQ29620418
Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndromeQ29620423
Proper folding and endoplasmic reticulum to golgi transport of tyrosinase are induced by its substrates, DOPA and tyrosineQ31735253
Small Gtpase rab3A is associated with melanosomes in melanoma cellsQ31816346
Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.Q33285661
Current understanding on the role of retinal pigment epithelium and its pigmentationQ33716211
Regulated secretion from hemopoietic cellsQ33745488
Clinical, molecular, and cell biological aspects of Chediak-Higashi syndromeQ33755016
Biochemical control of melanogenesis and melanosomal organizationQ33760835
Molecular mechanisms of pigment transport in melanophoresQ33762752
Adaptors for clathrin-mediated trafficQ33804351
Membrane trafficking, organelle transport, and the cytoskeleton.Q33840274
Class V myosins.Q33866590
Two genes are responsible for Griscelli syndrome at the same 15q21 locus.Q33892373
Heterozygous HPS1 mutations in a case of Hermansky-Pudlak syndrome with giant melanosomes.Q33916390
Lysosome-related organellesQ33956953
Myosin VI: roles for a minus end-directed actin motor in cellsQ34038023
Mutation of a new gene causes a unique form of Hermansky-Pudlak syndrome in a genetic isolate of central Puerto RicoQ34084038
Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medakaQ34085466
Hermansky-Pudlak syndrome and related disorders of organelle formationQ34156519
Ypt and Rab GTPases: insight into functions through novel interactionsQ34309095
Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va geneQ34431158
The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cellsQ34687885
The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cellsQ34714968
Myosin-V stepping kinetics: a molecular model for processivityQ35207228
Vacuole acidification is required for trans-SNARE pairing, LMA1 release, and homotypic fusionQ35642673
On the possible function of coated vesicles in melanogenesis of the regenerating fowl featherQ36192576
Mannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesiclesQ36289154
Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function In vivoQ36328552
Intracellular sorting and targeting of melanosomal membrane proteins: identification of signals for sorting of the human brown locus protein, gp75Q36382701
The mouse pale ear (ep) mutation is the homologue of human Hermansky-Pudlak syndromeQ36560640
Di-leucine signals mediate targeting of tyrosinase and synaptotagmin to synaptic-like microvesicles within PC12 cells.Q36941351
The mammalian AP-3 adaptor-like complex mediates the intracellular transport of lysosomal membrane glycoproteins.Q38331973
Melanosomes are specialized members of the lysosomal lineage of organelles.Q40447735
Actin- and microtubule-dependent organelle motors: interrelationships between the two motility systems.Q40529200
Weibel-Palade body membrane proteins exhibit differential trafficking after exocytosis in endothelial cellsQ40826415
Membrane association and targeting of prenylated Ras-like GTPasesQ40857389
Rab5 regulates motility of early endosomes on microtubulesQ40916867
A cytoplasmic sequence in human tyrosinase defines a second class of di-leucine-based sorting signals for late endosomal and lysosomal deliveryQ40959249
Direct interaction of microtubule- and actin-based transport motorsQ40975760
Motors and membrane traffic.Q41334437
Kinesin participates in melanosomal movement along melanocyte dendritesQ42484188
Three modes of melanosome transfers in Caucasian facial skin: hypothesis based on an ultrastructural study.Q42493458
A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growthQ42820599
Tyrosinase stabilization by Tyrp1 (the brown locus protein).Q42824469
The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organellesQ42919564
Rab27a is required for regulated secretion in cytotoxic T lymphocytesQ42947316
Intracellular distribution and late endosomal effects of the ocular albinism type 1 gene product: consequences of disease-causing mutations and implications for melanosome biogenesisQ43549011
Mislocalization of melanosomal proteins in melanocytes from mice with oculocutaneous albinism type 2.Q43624874
The Hermansky-Pudlak syndrome (HPS) protein is part of a high molecular weight complex involved in biogenesis of early melanosomesQ47247902
The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamilyQ48745906
Two-headed binding of a processive myosin to F-actin.Q52863984
The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiencyQ55951827
Secretory Lysosome Biogenesis in Cytotoxic T Lymphocytes from Normal and Chediak Higashi Syndrome PatientsQ58019241
Chemical Composition and Terminology Of Specialized Organelles (Melanosomes and Melanin Granules) in Mammalian MelanocytesQ59094998
Oa1 knock-out: new insights on the pathogenesis of ocular albinism type 1.Q61409124
P433issue10
P921main subjectmelanosomeQ1065756
P304page(s)738-748
P577publication date2001-10-01
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleThe melanosome: membrane dynamics in black and white
P478volume2

Reverse relations

cites work (P2860)
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