The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function

scientific article

The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.1600-0749.2005.00269.X
P932PMC publication ID2788625
P698PubMed publication ID16162173
P5875ResearchGate publication ID7601108

P50authorGraça RaposoQ10291449
P2093author name stringMichael S Marks
Alexander C Theos
Steven T Truschel
P2860cites workFurin mediates enhanced production of fibrillogenic ABri peptides in familial British dementiaQ22010692
Pmel17 initiates premelanosome morphogenesis within multivesicular bodiesQ24291864
MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomesQ24294239
The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteinsQ24305089
nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenograftsQ24308773
Cloning and expression of the gene for the melanoma-associated ME20 antigenQ24313227
Epitope mapping of the melanosomal matrix protein gp100 (PMEL17): rapid processing in the endoplasmic reticulum and glycosylation in the early Golgi compartmentQ24337303
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formationQ24338441
A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3.Q24533159
The structure of a PKD domain from polycystin-1: implications for polycystic kidney diseaseQ24533517
A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12Q24560368
Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejectionQ24561706
Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locusQ24633925
Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cellsQ24671475
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid raftsQ24675729
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymesQ24675937
Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytesQ24676041
MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanomaQ24685652
Assembly of asparagine-linked oligosaccharidesQ28131690
Proteomic analysis of early melanosomes: identification of novel melanosomal proteinsQ28184384
Protein folding and misfoldingQ28235199
Folding proteins in fatal waysQ28235206
Identification and characterization of the genes encoding human and mouse osteoactivinQ28236327
The release of intact oligosaccharides from specific glycoproteins by endo-beta-N-acetylglucosaminidase HQ28237773
Genomic organization and sequence of D12S53E (Pmel 17), the human homologue of the mouse silver (si) locusQ28275302
Polymerization of 5,6-dihydroxyindole-2-carboxylic acid to melanin by the pmel 17/silver locus proteinQ28277065
Genomic organization and FISH mapping of human Pmel 17, the putative silver locusQ28286162
Molecular characterization of the melanocyte lineage-specific antigen gp100Q28286527
Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycansQ28513288
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblastsQ28573446
The fine structure of melanogenesis in coat color mutants of the mouseQ28585604
The proprotein convertasesQ28609903
The biogenesis of multivesicular endosomesQ29620561
Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cellsQ30811481
The cDNA RPE1 and monoclonal antibody HMB-50 define gene products preferentially expressed in retinal pigment epitheliumQ31042537
Tubular early endosomal networks in AtT20 and other cellsQ33404259
Complete sequence and expression of a cDNA encoding a chicken 115-kDa melanosomal matrix proteinQ33412255
Ubiquitylation of a melanosomal protein by HECT-E3 ligases serves as sorting signal for lysosomal degradationQ33734547
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-primingQ33936302
A model for melanosome biogenesis based on the purification and analysis of early melanosomesQ33943742
Exosomes: endosomal-derived vesicles shipping extracellular messagesQ33980024
Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca(2+) stabilizationQ34078036
The color loci of mice--a genetic centuryQ34214082
Protein sorting into multivesicular endosomesQ34218897
The mouse silver locus encodes a single transcript truncated by the silver mutation.Q47901792
The melanosome: the perfect model for cellular responses to the environment.Q50494109
Modulation of melanogenic protein expression during the switch from eu- to pheomelanogenesis.Q50519597
The Pmel 17/silver locus protein. Characterization and investigation of its melanogenic function.Q50522749
Characterization and subcellular localization of human Pmel 17/silver, a 110-kDa (pre)melanosomal membrane protein associated with 5,6,-dihydroxyindole-2-carboxylic acid (DHICA) converting activity.Q52547540
Chicken genomics: feather-pecking and victim pigmentation.Q53764349
Multifocal alveolar hyperplasia associated with lymphangioleiomyomatosis in tuberous sclerosisQ55981831
Pro-opiomelanocortin-Related Peptides, Prohormone Convertases 1 and 2 and the Regulatory Peptide 7B2 are Present in Melanosomes of Human MelanocytesQ57268725
Chemical Composition and Terminology Of Specialized Organelles (Melanosomes and Melanin Granules) in Mammalian MelanocytesQ59094998
The expression of melanosomal matrix protein in the transdifferentiation of pigmented epithelial cells into lens cellsQ61448137
Comparison of Eumelanogenesis and Pheomelanogenesis in Retinal and Follicular Melanocytes; Role of Vesculo-globular Bodies in Melanosome DifferentiationQ66926700
Melanosome formation in the goldfish: the role of multivesicular bodiesQ67508336
Anti-melanoma monoclonal antibody HMB45 identifies an oncofetal glycoconjugate associated with immature melanosomesQ68080026
Identification of a secreted Mr 95,000 glycoprotein in human melanocytes and melanomas by a melanocyte specific monoclonal antibodyQ68266431
A melanocyte-specific complementary DNA clone whose expression is inducible by melanotropin and isobutylmethyl xanthineQ69018976
Golgi-melanosome relationship in human melanoma in vitroQ69870668
Pigmentation genes: the tyrosinase gene family and the pmel 17 gene familyQ70560378
Processing of pro-islet amyloid polypeptide (proIAPP) by the prohormone convertase PC2Q70888451
Mapping of the human gene for a melanocyte protein Pmel 17 (D12S53E) to chromosome 12q13–q14Q71846598
Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regressionQ72133139
Genetic variations in the fine structure and ontogeny of mouse melanin granulesQ72757315
Identification of a mammalian melanosomal matrix glycoproteinQ72866054
New insights on the structure of the mouse silver locus and on the function of the silver proteinQ73101242
Angiomyolipoma: immunohistochemical and ultrastructural study of 14 casesQ73738523
Monotypic epithelioid angiomyolipoma of the liverQ73738801
Regulation of the murine silver locus product (gp87) by the hypopigmenting cytokines TGF-beta1 and TNF-alphaQ73857817
Megakaryocyte dense granule components are sorted in multivesicular bodiesQ73877070
Heterogeneous expression of melanoma-associated antigens and HLA-A2 in metastatic melanoma in vivoQ74185524
Clear cell myomelanocytic tumor of the falciform ligament/ligamentum teres: a novel member of the perivascular epithelioid clear cell family of tumors with a predilection for children and young adultsQ74284410
Expression of MAGE, gp100 and tyrosinase genes in uveal melanoma cell linesQ74330389
The melanosome: a distinctive subcellular particle of mammalian melanocytes and the site of melanogenesisQ79027441
High expression of immunotherapy candidate proteins gp100, MART-1, tyrosinase and TRP-1 in uveal melanomaQ95815127
Interaction of melanosomal proteins with melanin.Q34295081
The endocytic pathway: a mosaic of domainsQ34389525
The melanosome: membrane dynamics in black and whiteQ34389530
The Dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 geneQ34569730
The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesisQ34585581
The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cellsQ34714968
Mouse silver mutation is caused by a single base insertion in the putative cytoplasmic domain of Pmel 17Q34734169
Concepts and principles of O-linked glycosylationQ34749639
Cancer vaccines: progress reveals new complexitiesQ34774541
Amino-acid sequence of activation cleavage site in plasminogen: homology with "pro" part of prothrombinQ35083640
Amyloid as a natural productQ35125908
Pathological and functional amyloid formation orchestrated by the secretory pathwayQ35607730
Identification of a melanosomal matrix protein encoded by the murine si (silver) locus using "organelle scanning".Q35613965
Melanosome transfer to and translocation in the keratinocyteQ35645880
Characterization of a new melanocyte-specific gene (QNR-71) expressed in v-myc-transformed quail neuroretina.Q35900184
Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoformQ36235271
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesisQ36323476
Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomesQ36365285
Intracellular sorting and targeting of melanosomal membrane proteins: identification of signals for sorting of the human brown locus protein, gp75Q36382701
Cells release prions in association with exosomesQ36448448
Characterization of genes modulated during pheomelanogenesis using differential displayQ36487455
Isolation of novel HLA-DR restricted potential tumor-associated antigens from the melanoma cell line FM3.Q36874107
A novel splice variant of Pmel17 expressed by human melanocytes and melanoma cells lacking some of the internal repeats.Q37476322
Trans-Golgi reticulumQ37638812
Differential processing and secretion of the melanoma-associated ME20 antigenQ38308167
Melanosomes are specialized members of the lysosomal lineage of organelles.Q40447735
Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.Q40762561
Subcellular localization of the melanoma-associated protein Melan-AMART-1 influences the processing of its HLA-A2-restricted epitopeQ40781224
Comparative analysis of the in vivo expression of tyrosinase, MART-1/Melan-A, and gp100 in metastatic melanoma lesions: implications for immunotherapy.Q40870788
A cytoplasmic sequence in human tyrosinase defines a second class of di-leucine-based sorting signals for late endosomal and lysosomal deliveryQ40959249
The tyrosinase tail mediates sorting to the lysosomal compartment in MDCK cells via a di-leucine and a tyrosine-based signal.Q40990231
Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules.Q41050738
Heterogeneous expression of immunotherapy candidate proteins gp100, MART-1, and tyrosinase in human melanoma cell lines and in human melanocytic lesionsQ41097918
Transcription of the gene encoding melanoma-associated antigen gp100 in tissues and cell lines other than those of the melanocytic lineageQ41136807
Endosome-lysosomes, ubiquitin and neurodegeneration.Q41154900
Anti-melanoma monoclonal antibody HMB-45 on enhanced chemiluminescence-western blotting recognizes a 30-35 kDa melanosome-associated sialated glycoproteinQ41178136
Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytesQ41483867
Melanocyte lineage-specific antigens recognized by monoclonal antibodies NKI-beteb, HMB-50, and HMB-45 are encoded by a single cDNA.Q41513276
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartmentsQ41695026
Effects of the developmental colour mutations silver and recessive spotting on proliferation of diploid and immortal mouse melanocytes in cultureQ41770891
Melanin granules of retinal pigment epithelium are connected with the lysosomal degradation pathwayQ41924544
A monoclonal antibody specific for cells of the melanocyte lineageQ41932182
Inhibition of melanogenesis in response to oxidative stress: transient downregulation of melanocyte differentiation markers and possible involvement of microphthalmia transcription factorQ42508314
Acidic pH and detergents enhance in vitro conversion of human brain PrPC to a PrPSc-like formQ44088944
Comparison of five antimelanoma antibodies for identification of melanocytic cells on tissue sections in routine dermatopathologyQ44213548
Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine developmentQ44672678
P433issue5
P304page(s)322-336
P577publication date2005-10-01
P1433published inPigment Cell & Melanoma ResearchQ762851
P1476titleThe Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function
P478volume18

Reverse relations

cites work (P2860)
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