| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S1877-1173(09)88004-6 |
| P698 | PubMed publication ID | 20374726 |
| P50 | author | Kimberley A. Beaumont | Q50190182 |
| P2093 | author name string | Richard A Sturm | |
| Yan Yan Liu | |||
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| A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus | Q24555704 | ||
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| A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color | Q24656429 | ||
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| Diminishment of alpha-MSH anti-inflammatory activity in MC1r siRNA-transfected RAW264.7 macrophages | Q35227663 | ||
| The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression. | Q28348605 | ||
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| Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome | Q29620423 | ||
| Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells | Q31845692 | ||
| Supranuclear Melanin Caps Reduce Ultraviolet Induced DNA Photoproducts in Human Epidermis | Q32064545 | ||
| Nucleotide diversity and population differentiation of the melanocortin 1 receptor gene, MC1R. | Q33327597 | ||
| A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation | Q33335147 | ||
| ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma | Q33335710 | ||
| Improving melanoma classification by integrating genetic and morphologic features | Q33340639 | ||
| Lack of somatic alterations of MC1R in primary melanoma | Q33672304 | ||
| MC1R variants increase risk of melanomas harboring BRAF mutations. | Q33715143 | ||
| Melanocortin 1 receptor variation in the domestic dog. | Q33884069 | ||
| MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes | Q59096765 | ||
| MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk | Q61946725 | ||
| Nle4DPhe7α-Melanocyte-Stimulating Hormone Increases the Eumelanin:Phaeomelanin Ratio in Cultured Human Melanocytes | Q62661109 | ||
| Effects of melanocyte-stimulating hormone on tyrosinase expression and melanin synthesis in hair follicular melanocytes of the mouse | Q62661180 | ||
| The Arg160Trp Allele of Melanocortin-1 Receptor Gene Might Protect Against Vitiligo | Q62661943 | ||
| Increasing incidence of cutaneous melanoma in Queensland, Australia | Q64896176 | ||
| The expression of functional MSH receptors on cultured human melanocytes | Q67509847 | ||
| MSH receptor expression and the relationship to melanogenesis and metastatic activity in B16 melanoma | Q67855367 | ||
| Quantification of MSH receptors on mouse melanoma tissue by receptor autoradiography | Q68252464 | ||
| Regulation of tyrosinase synthesis and its processing in the hair follicular melanocytes of the mouse during eumelanogenesis and phaeomelanogenesis | Q69216881 | ||
| Golgi-melanosome relationship in human melanoma in vitro | Q69870668 | ||
| Atmospheric photochemistry | Q70124948 | ||
| Expression of melanocortin 1 receptor in periaqueductal gray matter | Q70986697 | ||
| Proopiomelanocortin gene product regulation in keratinocytes | Q71049519 | ||
| Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B | Q71469228 | ||
| Alpha-melanocyte stimulating hormone-induced pigmentation is blocked by depletion of protein kinase C | Q71530077 | ||
| The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor | Q71570263 | ||
| A comparative study of the physical and chemical properties of melanins isolated from human black and red hair | Q71668136 | ||
| Hydrogen peroxide generation associated with the oxidations of the eumelanin precursors 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid | Q71759513 | ||
| Mitogen-activated protein kinase pathway and AP-1 are activated during cAMP-induced melanogenesis in B-16 melanoma cells | Q71823491 | ||
| Val92Met variant of the melanocyte stimulating hormone receptor gene | Q71835119 | ||
| The detection of cyclobutane thymine dimers, (6-4) photolesions and the Dewar photoisomers in sections of UV-irradiated human skin using specific antibodies, and the demonstration of depth penetration effects | Q71962237 | ||
| Cumulative effects from repeated exposures to suberythemal doses of UVB and UVA in human skin | Q72411783 | ||
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| Structural and Functional Requirements for Agonist-induced Internalization of the Human Platelet-activating Factor Receptor | Q73596201 | ||
| The involvement of p38 mitogen-activated protein kinase in the alpha-melanocyte stimulating hormone (alpha-MSH)-induced melanogenic and anti-proliferative effects in B16 murine melanoma cells | Q74062813 | ||
| Phaeomelanin versus eumelanin as a chemical indicator of ultraviolet sensitivity in fair-skinned subjects at high risk for melanoma: a pilot study | Q74330411 | ||
| Aberrant pH of melanosomes in pink-eyed dilution (p) mutant melanocytes | Q74347101 | ||
| G protein-coupled receptor kinases | Q77366588 | ||
| Modulation of melanocyte-stimulating hormone receptor expression on normal human melanocytes: evidence for a regulatory role of ultraviolet B, interleukin-1α, interleukin-1β, endothelin-1 and tumour necrosis factor-α | Q77393471 | ||
| Loss of function mutations of the human melanocortin 1 receptor are common and are associated with red hair | Q77994831 | ||
| Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin | Q78199477 | ||
| Melanocortin-3-receptor gene variants in morbid obesity | Q78807346 | ||
| Uveal melanocytes do not respond to or express receptors for alpha-melanocyte-stimulating hormone | Q79143839 | ||
| MC1R germline variants confer risk for BRAF-mutant melanoma | Q79815917 | ||
| Polymorphism patterns in the promoter region of the MC1R gene are associated with development of freckles and solar lentigines | Q80198764 | ||
| Impact of homozygosity of R151C variant of MC1r in human hair follicle melanocytes | Q80236188 | ||
| Pharmacological analyses of two naturally occurring porcine melanocortin-4 receptor mutations in domestic pigs | Q80666627 | ||
| P gene mutations associated with oculocutaneous albinism type II (OCA2) | Q81403835 | ||
| The D84E variant of the alpha-MSH receptor 1 gene is associated with cutaneous malignant melanoma early onset | Q81702953 | ||
| alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes | Q81756817 | ||
| MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population | Q81926997 | ||
| Germline MC1R variants and BRAF mutant melanoma | Q81957705 | ||
| Role of the conserved NPxxY motif of the 5-HT2A receptor in determining selective interaction with isoforms of ADP-ribosylation factor (ARF) | Q82872246 | ||
| Homologous regulation of melanocortin-1 receptor (MC1R) expression in melanoma tumor cells in vivo | Q94164461 | ||
| Dimerization of G-protein-coupled receptors: roles in signal transduction | Q35592680 | ||
| Gamma-MSH, sodium metabolism, and salt-sensitive hypertension | Q35648417 | ||
| Targeting melanocortin receptors as a novel strategy to control inflammation. | Q35682900 | ||
| Melanocortin receptors and erectile function | Q35776539 | ||
| Temperature-sensitive tyrosinase associated with peripheral pigmentation in oculocutaneous albinism | Q35820377 | ||
| Pharmacological chaperone action on G-protein-coupled receptors. | Q35879860 | ||
| Small GTP-binding protein-coupled receptors | Q35928481 | ||
| Inflammation, gene mutation and photoimmunosuppression in response to UVR-induced oxidative damage contributes to photocarcinogenesis | Q36062321 | ||
| Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation | Q36062581 | ||
| The relation between melanocortin 1 receptor (MC1R) variation and the generation of phenotypic diversity in the cutaneous response to ultraviolet radiation | Q36166642 | ||
| Molecular mechanisms of the neural melanocortin receptor dysfunction in severe early onset obesity. | Q36173486 | ||
| Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft für Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels | Q36189284 | ||
| The regulatory mechanisms of export trafficking of G protein-coupled receptors. | Q36192980 | ||
| Regulation of tyrosinase in human melanocytes grown in culture | Q36207702 | ||
| Obesity-associated mutations in the melanocortin 4 receptor provide novel insights into its function | Q36220161 | ||
| Regulation of tyrosinase gene expression by cAMP in B16 melanoma cells involves two CATGTG motifs surrounding the TATA box: implication of the microphthalmia gene product | Q36237223 | ||
| The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function | Q36257261 | ||
| Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes | Q36288243 | ||
| Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis | Q36323476 | ||
| The tale of the telomere: implications for prevention and treatment of skin cancers | Q36346181 | ||
| The molecular regulation of organelle transport in mammalian retinal pigment epithelial cells | Q36416475 | ||
| Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis. | Q36476486 | ||
| Characterization of genes modulated during pheomelanogenesis using differential display | Q36487455 | ||
| The quest for the mechanism of melanin transfer | Q36513235 | ||
| Interactions between SNP alleles at multiple loci contribute to skin color differences between caucasoid and mongoloid subjects | Q36529026 | ||
| A golden age of human pigmentation genetics | Q36542192 | ||
| Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system | Q36557845 | ||
| Anti-inflammatory and anti-invasive effects of α-melanocyte-stimulating hormone in human melanoma cells | Q36671614 | ||
| The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. | Q36693902 | ||
| Physiological roles of G protein-coupled receptor kinases and arrestins | Q36737680 | ||
| Characterisation of D117A and H260A mutations in the melanocortin 1 receptor | Q36852318 | ||
| Molecular modeling of melanocortin receptors | Q36855746 | ||
| Regulation of eumelanin/pheomelanin synthesis and visible pigmentation in melanocytes by ligands of the melanocortin 1 receptor | Q36925751 | ||
| Crystal structure of the human beta2 adrenergic G-protein-coupled receptor | Q27648868 | ||
| Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants | Q28115855 | ||
| Genetic association and cellular function of MC1R variant alleles in human pigmentation | Q28185942 | ||
| Expression of the B-cell proliferation marker MUM1 by melanocytic lesions and comparison with S100, gp100 (HMB45), and MelanA | Q28201955 | ||
| Identification of Aim-1 as the underwhiteMouse Mutant and Its Transcriptional Regulation by MITF | Q28204392 | ||
| The role of Kit-ligand in melanocyte development and epidermal homeostasis | Q28204716 | ||
| The patterns of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour | Q28205025 | ||
| The melanocortin system | Q28205910 | ||
| A novel melanocortin 3 receptor gene (MC3R) mutation associated with severe obesity | Q28206459 | ||
| The mouse p (pink-eyed dilution) and human P genes, oculocutaneous albinism type 2 (OCA2), and melanosomal pH | Q28213415 | ||
| The etiology of oculocutaneous albinism (OCA) type II: the pink protein modulates the processing and transport of tyrosinase | Q28218945 | ||
| Molecular genetics of human pigmentation diversity | Q28238551 | ||
| Melanocortin-5 receptor deficiency promotes defensive behavior in male mice | Q28239723 | ||
| Melanocortin-5 receptor deficiency reduces a pheromonal signal for aggression in male mice | Q28246188 | ||
| Molecular cloning, expression, and characterization of a fifth melanocortin receptor | Q28253614 | ||
| Genetic determinants of hair, eye and skin pigmentation in Europeans | Q28254206 | ||
| A melanocortin 1 receptor allele suggests varying pigmentation among Neanderthals | Q28254945 | ||
| Racial Differences in the Fate of Melanosomes in Human Epidermis | Q28256038 | ||
| The mouse pink-eyed dilution gene: association with human Prader-Willi and Angelman syndromes | Q28257131 | ||
| Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides | Q28257807 | ||
| Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression | Q28263436 | ||
| Cloning and functional characterization of a family of receptors for the melanotropic peptides | Q28263520 | ||
| Molecular cloning of a novel human melanocortin receptor | Q28263897 | ||
| Microphthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transport | Q28269029 | ||
| Genetic evidence for the convergent evolution of light skin in Europeans and East Asians | Q28279959 | ||
| SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans | Q28287208 | ||
| Analysis of cultured human melanocytes based on polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P loci | Q28288300 | ||
| Promoter polymorphisms in the MATP (SLC45A2) gene are associated with normal human skin color variation | Q28292797 | ||
| Melanocortin receptors form constitutive homo- and heterodimers | Q28296933 | ||
| A missense mutation in the gene for melanocyte-stimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses | Q28301323 | ||
| Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2 | Q28302878 | ||
| Novel MITF targets identified using a two-step DNA microarray strategy | Q28303403 | ||
| Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain | Q28307200 | ||
| Role of G protein-coupled receptor kinases in the homologous desensitization of the human and mouse melanocortin 1 receptors. | Q40471499 | ||
| G protein-coupled receptor endocytosis in ADP-ribosylation factor 6-depleted cells. | Q40482254 | ||
| alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage | Q40486926 | ||
| Agonist-independent, high constitutive activity of the human melanocortin 1 receptor. | Q40536387 | ||
| Skin cancer in African Americans | Q40559262 | ||
| Functional and phylogenetic analyses of a melanocortin-4 receptor mutation in domestic pigs. | Q40597839 | ||
| Molecular and developmental genetics of mouse coat color | Q40613974 | ||
| Rate limiting factors in melanocortin 1 receptor signalling through the cAMP pathway | Q40638678 | ||
| Agouti signal protein regulation in human melanoma cells | Q40678792 | ||
| Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations | Q40681335 | ||
| Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function. | Q40684596 | ||
| Ligand-dependent activation of the melanocortin 5 receptor: cAMP production and ryanodine receptor-dependent elevations of [Ca(2+)](I). | Q40757866 | ||
| Thr40 and Met122 are new partial loss-of-function natural mutations of the human melanocortin 1 receptor. | Q40768939 | ||
| A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells. | Q40811578 | ||
| Impaired resensitization and recycling of the cholecystokinin receptor by co-expression of its second intracellular loop | Q40840230 | ||
| Functional characterization of naturally occurring mutations of the human adrenocorticotropin receptor: poor correlation of phenotype and genotype | Q40936201 | ||
| Proopiomelanocortin, its derived peptides, and the skin | Q40964373 | ||
| alpha-Melanocyte-stimulating hormone signaling regulates expression of microphthalmia, a gene deficient in Waardenburg syndrome | Q40992351 | ||
| Immunoreactive alpha-melanotropin as an autocrine effector in human melanoma cells | Q41120662 | ||
| Agouti regulation of intracellular calcium: role of melanocortin receptors | Q41122711 | ||
| Temperature sensitivity of some mutants of the lutropin/choriogonadotropin receptor | Q41143763 | ||
| Localization of ACTH receptor mRNA by in situ hybridization in mouse adrenal gland | Q41165786 | ||
| Molecular cloning of a mouse melanocortin 5 receptor gene widely expressed in peripheral tissues. | Q41473442 | ||
| The contribution of melanocortin 1 receptor gene polymorphisms and the agouti signalling protein gene 8818A>G polymorphism to cutaneous melanoma and basal cell carcinoma in a Polish population. | Q42439112 | ||
| Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to alpha-melanotropin | Q42439507 | ||
| α-MSH causes a small rise in cAMP but has no effect on basal or ultraviolet-stimulated melanogenesis in human melanocytes | Q42465878 | ||
| MC1R and PTCH gene polymorphism in French patients with basal cell carcinomas. | Q42494105 | ||
| Melanocortin 1 receptor variants and skin cancer risk | Q42495860 | ||
| Human melanocytes as a target tissue for hormones: in vitro studies with 1 alpha-25, dihydroxyvitamin D3, alpha-melanocyte stimulating hormone, and beta-estradiol | Q42502557 | ||
| Influence of alpha-melanocyte-stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes | Q42513562 | ||
| MC1R variants associated susceptibility to basal cell carcinoma of skin: interaction with host factors and XRCC3 polymorphism | Q42522286 | ||
| Involvement of mi-transcription factor in expression of alpha-melanocyte-stimulating hormone receptor in cultured mast cells of mice | Q42806933 | ||
| Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive | Q42816994 | ||
| Melanocortin 1 receptor (MC1R) gene variants may increase the risk of melanoma in France independently of clinical risk factors and UV exposure | Q43073877 | ||
| Effects of melanin-induced free radicals on the isolated rat peritoneal mast cells | Q43427729 | ||
| Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. | Q43581712 | ||
| Gene admixture in the silk road region of China: evidence from mtDNA and melanocortin 1 receptor polymorphism. | Q43604425 | ||
| Dermoscopic features of melanomas associated with MC1R variants in Spanish CDKN2A mutation carriers. | Q43922716 | ||
| The architecture of black and white facial skin | Q44090181 | ||
| Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation | Q44230285 | ||
| Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies. | Q44445179 | ||
| The IFPCS presidential lecture: a chemist's view of melanogenesis | Q44445183 | ||
| Appropriate polarization following pharmacological rescue of V2 vasopressin receptors encoded by X-linked nephrogenic diabetes insipidus alleles involves a conformation of the receptor that also attains mature glycosylation | Q44489740 | ||
| Regulation of melanocortin 1 receptor expression at the mRNA and protein levels by its natural agonist and antagonist | Q44590688 | ||
| Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma | Q44634512 | ||
| Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect | Q44856982 | ||
| Melanocortin receptor-1 gene polymorphisms and the risk of cutaneous melanoma in a low-risk southern European population. | Q44891693 | ||
| Susceptibility and outcome in MS: associations with polymorphisms in pigmentation-related genes | Q44947259 | ||
| The relationship between Na(+)/H(+) exchanger expression and tyrosinase activity in human melanocytes | Q44987216 | ||
| Comparison of structural and chemical properties of black and red human hair melanosomes | Q45123491 | ||
| Tyrosinase gene expression is regulated by p53. | Q45711352 | ||
| Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation. | Q45941047 | ||
| A polymorphism study of the human Agouti gene and its association with MC1R. | Q46159085 | ||
| Prolonged treatment of fair-skinned mice with topical forskolin causes persistent tanning and UV protection | Q46195629 | ||
| Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating | Q46249432 | ||
| DNA polymorphism and selection at the melanocortin-1 receptor gene in normally pigmented southern African individuals. | Q46693239 | ||
| Pharmacologic chaperones as a potential treatment for X-linked nephrogenic diabetes insipidus | Q46828751 | ||
| Quantitative analysis of MC1R gene expression in human skin cell cultures | Q46899227 | ||
| Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes | Q46932007 | ||
| The human melanocortin-1 receptor locus: analysis of transcription unit, locus polymorphism and haplotype evolution | Q46968462 | ||
| The role of the DRY motif of human MC4R for receptor activation | Q47294474 | ||
| P304 | page(s) | 85-153 | |
| P577 | publication date | 2009-10-07 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Progress in Molecular Biology and Translational Science | Q15753415 |
| P1476 | title | The melanocortin-1 receptor gene polymorphism and association with human skin cancer | |
| P478 | volume | 88 |
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| Q57390889 | GSTP1 and MC1R in melanoma susceptibility |
| Q57391606 | GSTP1 does not modify MC1R effects on melanoma risk |
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| Q38206554 | MC1R and NR4A receptors in cellular stress and DNA repair: implications for UVR protection |
| Q43407531 | MC1R gene variants and sporadic malignant melanoma susceptibility in the Canary Islands population |
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| Q58608873 | Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH |
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| Q37715623 | Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands. |
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| Q50485708 | Simultaneous purifying selection on the ancestral MC1R allele and positive selection on the melanoma-risk allele V60L in south Europeans |
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