Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis

scientific article

Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1004368952
P356DOI10.1038/CDDIS.2012.119
P932PMC publication ID3434659
P698PubMed publication ID22914328
P5875ResearchGate publication ID230722180

P2093author name stringS Banerjee
A Roy
N P Basak
P2860cites workSuppression of erythroid but not megakaryocytic differentiation of human K562 erythroleukemic cells by notch-1.Q38312829
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells.Q39843637
PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1).Q40015626
The Polycomb Group protein EZH2 regulates actin polymerization in human prostate cancer cellsQ40032719
Delta-4 Notch ligand promotes erythroid differentiation of human umbilical cord blood CD34+ cellsQ40298943
Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1.Q40488277
The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphomaQ40813288
Forkhead family transcription factor FKHRL1 is expressed in human megakaryocytes. Regulation of cell cycling as a downstream molecule of thrombopoietin signalingQ40817308
Notch/Delta4 signaling inhibits human megakaryocytic terminal differentiation.Q42911718
Inhibition of TPO-induced MEK or mTOR activity induces opposite effects on the ploidy of human differentiating megakaryocytesQ46921346
Hemoglobin depletion from red blood cell cytosol reveals new proteins in 2-D gel-based proteomics study.Q50693269
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.Q52110894
Polycomb group protein ezh2 controls actin polymerization and cell signaling.Q53676862
Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.Q54341375
Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells In VitroQ58608565
Novel pathway for megakaryocyte production after in vivo conditional eradication of integrin IIb-expressing cellsQ61914128
Localization of protein disulfide isomerase to the external surface of the platelet plasma membraneQ72030923
Protein disulphide isomerase mediates platelet aggregation and secretionQ74624115
Human ligands of the Notch receptorQ22009037
Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte developmentQ24321429
Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2Q24550771
Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expressionQ24649008
Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromesQ27851571
Notch signaling: cell fate control and signal integration in developmentQ27861061
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domainQ28273268
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganizationQ28275839
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3Q28276951
Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1Q28295662
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet developmentQ28591602
FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesisQ28593448
Direct regulation of Gata3 expression determines the T helper differentiation potential of NotchQ28594879
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteinsQ29614507
Matrix-assisted laser desorption/ionization-tandem mass spectrometry with high resolution and sensitivity for identification and characterization of proteinsQ30837558
Ablation of Gata1 in adult mice results in aplastic crisis, revealing its essential role in steady-state and stress erythropoiesisQ33378569
Characterization and transplantation of induced megakaryocytes from hematopoietic stem cells for rapid platelet recovery by a two-step serum-free procedureQ33385716
Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathwayQ33390267
Inducible Fli-1 gene deletion in adult mice modifies several myeloid lineage commitment decisions and accelerates proliferation arrest and terminal erythrocytic differentiationQ33391552
The human EZH2 gene: genomic organisation and revised mapping in 7q35 within the critical region for malignant myeloid disorders.Q33899402
Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2Q33919156
Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage developmentQ34197865
Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancerQ34409667
Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cellsQ34541560
Regulatory effects of TLR2 on megakaryocytic cell functionQ35037420
Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specificationQ35153770
Notch signaling in T- and B-cell development.Q35692177
Paradigms of notch signaling in mammals.Q36317946
GATA-2 reinforces megakaryocyte development in the absence of GATA-1Q37334070
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.Q37673550
P304page(s)e380
P577publication date2012-08-23
P1433published inCell Death and DiseaseQ2197222
P1476titleNotch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis
P478volume3

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cites work (P2860)
Q50590487A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells.
Q38459854Acinar cell reprogramming: a clinically important target in pancreatic disease
Q38268131Alteration of mitochondrial proteome due to activation of Notch1 signaling pathway
Q33440774Arachidonic acid and Docosahexanoic acid enhance platelet formation from human apheresis-derived CD34+ cells
Q101574084Dengue virus infection impedes megakaryopoiesis in MEG-01 cells where the virus envelope protein interacts with the transcription factor TAL-1
Q43206558Differential regulation of MCM7 and its intronic miRNA cluster miR-106b-25 during megakaryopoiesis induced polyploidy
Q48325256EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer
Q42183956Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis
Q52328065Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.
Q49977670Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish
Q37400390FIE, a nuclear PRC2 protein, forms cytoplasmic complexes in Arabidopsis thaliana.
Q35009496Increased cytoplasmic localization of p27(kip1) and its modulation of RhoA activity during progression of chronic myeloid leukemia
Q89887059MEDEA-interacting protein LONG-CHAIN BASE KINASE 1 promotes pattern-triggered immunity in Arabidopsis thaliana
Q52716487Megakaryocyte lineage development is controlled by modulation of protein acetylation.
Q39085918Molecular cross talk between Notch1, Shh and Akt pathways during erythroid differentiation of K562 and HEL cell lines
Q99616121Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation
Q37654857Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation
Q88938326Notch2 and Proteomic Signatures in Mouse Neointimal Lesion Formation
Q50967021PI3K/AKT signaling inhibits NOTCH1 lysosome-mediated degradation.
Q48356099Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation

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