Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells

scientific article published on October 4, 2010

Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2010-05-286062
P8608Fatcat IDrelease_uysfzvntmbgqdfdtnul6eyaf6u
P953full work available at URLhttp://www.bloodjournal.org/cgi/content/abstract/116/26/5859
http://www.bloodjournal.org/content/bloodjournal/116/26/5859.full.pdf
https://doi.org/10.1182/blood-2010-05-286062
https://europepmc.org/articles/PMC3031382
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20921340/?tool=EBI
http://ashpublications.org/blood/article-pdf/116/26/5859/1489812/zh805210005859.pdf
P932PMC publication ID3031382
P698PubMed publication ID20921340
P5875ResearchGate publication ID47336539

P50authorRichard HumphriesQ39614832
Hans-Peter KiemQ88408730
Korashon L WattsQ117811736
P2093author name stringColleen Delaney
Irwin D. Bernstein
P2860cites workLMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1Q28210584
Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitutionQ33642298
Regulation of T cell fate by NotchQ33652483
Notch1 and T-cell development: insights from conditional knockout miceQ34207634
Results of unrelated umbilical cord blood hematopoietic stem cell transplant.Q34333803
Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cellsQ34350253
Notch signaling in lymphopoiesis.Q35101882
Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cellsQ37352817
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.Q37673550
Effects of HOXB4 overexpression on ex vivo expansion and immortalization of hematopoietic cells from different speciesQ40131427
Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitroQ40502047
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.Q40683787
Efficient gene transfer to hematopoietic repopulating cells using concentrated RD114-pseudotype vectors produced by human packaging cellsQ42831743
Augmentation of umbilical cord blood (UCB) transplantation with ex vivo-expanded UCB cells: results of a phase 1 trial using the AastromReplicell SystemQ44321385
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 proteinQ44714937
Sustained multilineage gene persistence and expression in dogs transplanted with CD34(+) marrow cells transduced by RD114-pseudotype oncoretrovirus vectorsQ45879975
Factors associated with outcomes of unrelated cord blood transplant: guidelines for donor choiceQ47860858
HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulationQ49033123
Prompt and durable engraftment in two older adult patients with high risk chronic myelogenous leukemia (CML) using ex vivo expanded and unmanipulated unrelated umbilical cord bloodQ56609915
Development of CD4+ CD25+ FoxP3+ regulatory T cells from cord blood hematopoietic progenitor cellsQ61727534
Co-culture of Umbilical Cord Blood CD34þ Cells with Human Mesenchymal Stem CellsQ62132656
Monoclonal antibody 12-8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursorsQ70012827
Immobilization of Notch ligand, Delta-1, is required for induction of notch signalingQ73167897
Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assayQ74263420
Transplantation of ex vivo expanded cord bloodQ74596740
Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoproteinQ79209073
Human mesenchymal stem cells improve ex vivo expansion of adult human CD34+ peripheral blood progenitor cells and decrease their allostimulatory capacityQ79798386
P433issue26
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)5859-5866
P577publication date2010-10-04
P1433published inBloodQ885070
P1476titleCombination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells
P478volume116

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cites work (P2860)
Q36915150CD34(+) expansion with Delta-1 and HOXB4 promotes rapid engraftment and transfusion independence in a Macaca nemestrina cord blood transplant model
Q37255041Concise review: ex vivo expansion of cord blood-derived hematopoietic stem and progenitor cells: basic principles, experimental approaches, and impact in regenerative medicine
Q35153770Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification
Q39646815Distinct but phenotypically heterogeneous human cell populations produce rapid recovery of platelets and neutrophils after transplantation
Q33722264Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates
Q42686916Gene therapy for Fanconi anemia: one step closer to the clinic.
Q41073482HOXA4 provides stronger engraftment potential to short-term repopulating cells than HOXB4.
Q37945718Hematopoietic stem cell expansion and gene therapy
Q36127912Hematopoietic stem cell expansion facilitates multilineage engraftment in a nonhuman primate cord blood transplantation model.
Q38035450Hematopoietic stem cell expansion: challenges and opportunities.
Q27023434Hematopoietic-stem-cell-based gene therapy for HIV disease
Q33853349Human CD8 T cells generated in vitro from hematopoietic stem cells are functionally mature.
Q24621696Molecular pathogenesis and clinical management of Fanconi anemia
Q37325713Notch signaling in hematopoietic cell transplantation and T cell alloimmunity.
Q34390123Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis
Q37654857Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation
Q33675855PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells.
Q99608524Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis
Q47872469The functional duality of HoxB4 in hematopoietic reconstituting cells

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