Effects of co-treatment with sulforaphane and autophagy modulators on uridine 5'-diphospho-glucuronosyltransferase 1A isoforms and cytochrome P450 3A4 expression in Caco-2 human colon cancer cells.

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Effects of co-treatment with sulforaphane and autophagy modulators on uridine 5'-diphospho-glucuronosyltransferase 1A isoforms and cytochrome P450 3A4 expression in Caco-2 human colon cancer cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OL.2014.2536
P932PMC publication ID4214451
P698PubMed publication ID25364403
P5875ResearchGate publication ID267754258

P50authorYing QingQ85898271
P2093author name stringMin Wang
Wei Han
Dong Wu
Shuo Chen
Yan-Qing Li
Jing-Yu Zhu
Ji-Zhuang Luo
Ying-Min Lin
P2860cites workMolecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemopreventionQ24657569
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptorQ24683260
The nuclear pregnane X receptor: a key regulator of xenobiotic metabolismQ28206406
Polymorphic expression of UDP-glucuronosyltransferase UGTlA gene in human colorectal cancerQ28487071
Methods in mammalian autophagy researchQ29547276
Autophagy in health and disease: a double-edged swordQ29618103
[Induction of uridine 5'-diphosphate-glucuronosyltransferase gene expression by sulforaphane and its mechanism: experimental study in human colon cancel cells].Q33216859
Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo modelQ33540928
Cytochrome P-450 3A4: regulation and role in drug metabolismQ33636632
Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expressionQ34000784
Cancer prevention with natural compoundsQ34131211
Epidemiological studies on brassica vegetables and cancer risk.Q34403425
Multi-targeted prevention of cancer by sulforaphaneQ34781826
Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanismQ36642707
Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.Q37000698
Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.Q37120639
Genetic polymorphism of metabolic enzymes P450 (CYP) as a susceptibility factor for drug response, toxicity, and cancer riskQ37542607
Role of autophagy in cancer preventionQ37898320
Autophagy and cell death signaling following dietary sulforaphane act independently of each other and require oxidative stress in pancreatic cancerQ39549461
Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cellsQ39644675
Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cellsQ39757793
Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cellsQ39787313
LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localizationQ40154056
Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cellsQ40272756
Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear faQ42133496
Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cellsQ44848191
The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobioticsQ44855764
Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cellsQ46492551
Dominant contribution of P450 3A4 to the hepatic carcinogenic activation of aflatoxin B1.Q53347532
The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor.Q54577544
Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytesQ73677689
Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A)Q82579267
Effects of phytochemicals sulforaphane on uridine diphosphate-glucuronosyltransferase expression as well as cell-cycle arrest and apoptosis in human colon cancer Caco-2 cellsQ84071767
P433issue6
P921main subjectautophagyQ288322
Caco-2Q5016050
colon cancerQ18555025
P304page(s)2407-2416
P577publication date2014-09-15
P1433published inOncology LettersQ20640514
P1476titleEffects of co-treatment with sulforaphane and autophagy modulators on uridine 5'-diphospho-glucuronosyltransferase 1A isoforms and cytochrome P450 3A4 expression in Caco-2 human colon cancer cells
P478volume8

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cites work (P2860)
Q36296248Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.
Q28067369Research progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanisms
Q59807366Sulforaphane from Cruciferous Vegetables: Recent Advances to Improve Glioblastoma Treatment
Q92889950Sulforaphane-induced epigenetic regulation of Nrf2 expression by DNA methyltransferase in human Caco-2 cells

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