The hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells

scientific article

The hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2012PLoSO...745210L
P356DOI10.1371/JOURNAL.PONE.0045210
P932PMC publication ID3441598
P698PubMed publication ID23028851
P5875ResearchGate publication ID231815195

P2093author name stringYang Li
Wei Chen
Yan Zhang
Rui Li
Rui Zhang
Guoxun Chen
Meredith Howell
P2860cites workSelection of insulinoma cell lines with resistance to interleukin-1beta- and gamma-interferon-induced cytotoxicity.Q52831934
How obesity causes diabetes in Zucker diabetic fatty ratsQ81066858
Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin actionQ83400620
Cloning of a cDNA encoding an aldehyde dehydrogenase and its expression in Escherichia coli. Recognition of retinal as substrateQ24321298
Leptin at 14 y of age: an ongoing storyQ24644972
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob miceQ28144106
Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesityQ28253424
ObesityQ28275029
Different agonist- and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mappingQ28378417
Mouse retinal dehydrogenase 4 (RALDH4), molecular cloning, cellular expression, and activity in 9-cis-retinoic acid biosynthesis in intact cellsQ28511745
Cloning of a cDNA encoding rat aldehyde dehydrogenase with high activity for retinal oxidationQ28566277
Retinoids induced Pck1 expression and attenuated insulin-mediated suppression of its expression via activation of retinoic acid receptor in primary rat hepatocytesQ28566684
Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retinaQ28590811
Obesity and the regulation of energy balanceQ30080025
Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometryQ33608656
Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gammaQ33911192
Insulin-regulated Srebp-1c and Pck1 mRNA expression in primary hepatocytes from zucker fatty but not lean rats is affected by feeding conditionsQ33952316
Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acidQ33958544
Liver lipid molecules induce PEPCK-C gene transcription and attenuate insulin action.Q34654641
Retinoid production and catabolism: role of diet in regulating retinol esterification and retinoic Acid oxidationQ35039368
Physiological insights into all-trans-retinoic acid biosynthesisQ35230732
Obesity prevalence in the United States--up, down, or sideways?Q35936302
Primary prevention of diabetes: what can be done and how much can be prevented?Q36067453
Retinaldehyde represses adipogenesis and diet-induced obesity.Q36444754
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetesQ36698641
Specificity of a retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter: consequences of both retinoic acid and thyroid hormone receptor bindingQ36737154
Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genesQ36943797
Selective versus total insulin resistance: a pathogenic paradoxQ37076798
Retinoids synergize with insulin to induce hepatic Gck expressionQ37212141
Human obesity as a heritable disorder of the central control of energy balanceQ37366385
Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.Q37388544
A retinoic acid response element is part of a pleiotropic domain in the phosphoenolpyruvate carboxykinase geneQ37428862
Experimental rat models to study the metabolic syndromeQ37561703
From carrot to clinic: an overview of the retinoic acid signaling pathwayQ37689018
Tissue-specific increases in endogenous all-trans retinoic acid: possible contributing factor in ethanol toxicityQ37801675
Roles of vitamin A status and retinoids in glucose and fatty acid metabolismQ37980154
Identification and charaterization of the second retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoterQ41216009
Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolitesQ41457470
Regulation of phosphoenolpyruvate carboxykinase gene expression by insulin. Use of the stable transfection approach to locate an insulin responsive sequenceQ42810951
Estrogen receptor alpha regulates retinaldehyde dehydrogenase 1 expression in rat anterior pituitary cellsQ43293785
Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetesQ43833528
Cloning of rat cytochrome P450RAI (CYP26) cDNA and regulation of its gene expression by all-trans-retinoic acid in vivoQ44020686
End of the line for cannabinoid receptor 1 as an anti-obesity target?Q46222437
RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesicle and olfactory pit during mouse development.Q47823331
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)e45210
P577publication date2012-09-13
P1433published inPLOS OneQ564954
P1476titleThe hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells
P478volume7

Reverse relations

cites work (P2860)
Q37666802Aldehyde dehydrogenase 1A1: friend or foe to female metabolism?
Q35231302Higher protein kinase C ζ in fatty rat liver and its effect on insulin actions in primary hepatocytes
Q35552633Inflammation rapidly modulates the expression of ALDH1A1 (RALDH1) and vimentin in the liver and hepatic macrophages of rats in vivo
Q34402668Retinaldehyde dehydrogenase 1 deficiency inhibits PPARγ-mediated bone loss and marrow adiposity
Q36962066Roles of Vitamin A Metabolism in the Development of Hepatic Insulin Resistance.
Q39063004The expression of Apoc3 mRNA is regulated by HNF4α and COUP-TFII, but not acute retinoid treatments, in primary rat hepatocytes and hepatoma cells
Q35221895Vitamin A and feeding statuses modulate the insulin-regulated gene expression in Zucker lean and fatty primary rat hepatocytes

Search more.