| P50 | author | Stefan R. Bornstein | Q17126504 |
| P2093 | author name string | Böttner A | |
| P2860 | cites work | Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development | Q24313582 |
| | Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids | Q24564222 |
| | Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA | Q24615066 |
| | A novel mutation in DAX1 causes delayed-onset adrenal insufficiency and incomplete hypogonadotropic hypogonadism | Q24621014 |
| | Dopamine beta-hydroxylase deficiency impairs cellular immunity | Q24650564 |
| | Functional and high level expression of human dopamine beta-hydroxylase in transgenic mice | Q28116226 |
| | Impaired maternal behavior in mice lacking norepinephrine and epinephrine | Q28507556 |
| | Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation | Q28508582 |
| | Ethanol-associated behaviors of mice lacking norepinephrine | Q28512775 |
| | Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia | Q28512871 |
| | Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development | Q28512911 |
| | Absence of dopaminergic control on melanotrophs leads to Cushing's-like syndrome in mice | Q28585405 |
| | Targeted Disruption of the Tyrosine Hydroxylase Locus Results in Severe Catecholamine Depletion and Perinatal Lethality in Mice | Q28585685 |
| | Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline | Q28585689 |
| | Noradrenaline is essential for mouse fetal development | Q28592319 |
| | Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase | Q28594210 |
| | Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety | Q29615160 |
| | Clinical review 104: Adrenocorticotropin (ACTH)- and non-ACTH-mediated regulation of the adrenal cortex: neural and immune inputs | Q33633274 |
| | Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis | Q33650414 |
| | Steroidogenic factor 1 (SF-1) is essential for endocrine development and function | Q33694890 |
| | Knocking out the stress response | Q33752947 |
| | Physiological roles of the leptin endocrine system: differences between mice and humans | Q33828756 |
| | Stress Hormones: Their Interaction and Regulation | Q34248023 |
| | The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis | Q34350872 |
| | Intraadrenal interactions in the regulation of adrenocortical steroidogenesis. | Q34466315 |
| | DNA binding of the glucocorticoid receptor is not essential for survival | Q34469789 |
| | Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. | Q34471162 |
| | Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation | Q35204601 |
| | Feeding behavior in dopamine-deficient mice | Q35735190 |
| | Haploinsufficiency of steroidogenic factor-1 in mice disrupts adrenal development leading to an impaired stress response. | Q35846316 |
| | Deletion of tyrosine hydroxylase gene reveals functional interdependence of adrenocortical and chromaffin cell system in vivo | Q35854459 |
| | Corticotropin-releasing hormone deficiency unmasks the proinflammatory effect of epinephrine | Q36393230 |
| | Genes for human catecholamine-synthesizing enzymes | Q36538530 |
| | Genetic alteration of catecholamine specificity in transgenic mice. | Q36850820 |
| | Impaired diurnal adrenal rhythmicity restored by constant infusion of corticotropin-releasing hormone in corticotropin-releasing hormone-deficient mice | Q37368833 |
| | Excess corticotropin releasing hormone-binding protein in the hypothalamic-pituitary-adrenal axis in transgenic mice | Q37380244 |
| | Norepinephrine is required for leptin effects on gene expression in brown and white adipose tissue | Q38320143 |
| | Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells. | Q39225643 |
| | Knockout mice | Q40966754 |
| | CRH overproduction in transgenic mice: behavioral and immune system modulation | Q40971022 |
| | Production of corticotropin-releasing hormone-deficient mice by targeted mutation in embryonic stem cells | Q40971028 |
| | Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2. | Q41727428 |
| | Feedback control of glucocorticoid production is established during fetal development | Q41941529 |
| | Survival of steroid 21-hydroxylase-deficient mice without endogenous corticosteroids after neonatal treatment and genetic rescue by transgenesis as a model system for treatment of congenital adrenal hyperplasia in humans | Q43645643 |
| | Targeted ablation of pituitary pre-proopiomelanocortin cells by herpes simplex virus-1 thymidine kinase differentially regulates mRNAs encoding the adrenocorticotropin receptor and aldosterone synthase in the mouse adrenal gland | Q44859264 |
| | Restoration of adrenal steroidogenesis by adenovirus-mediated transfer of human cytochromeP450 21-hydroxylase into the adrenal gland of21-hydroxylase-deficient mice | Q45864075 |
| | The pathophysiology and genetics of congenital lipoid adrenal hyperplasia. | Q45931596 |
| | Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior. | Q46073460 |
| | Pituitary-directed leukemia inhibitory factor transgene causes Cushing's syndrome: neuro-immune-endocrine modulation of pituitary development | Q46079216 |
| | Modulation of hypothalamic-pituitary-adrenal function by transgenic expression of interleukin-6 in the CNS of mice. | Q46163823 |
| | Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice | Q46724358 |
| | Visualization and ablation of phenylethanolamine N-methyltransferase producing cells in transgenic mice | Q48078154 |
| | Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene | Q48526900 |
| | Endocrine profile and neuroendocrine challenge tests in transgenic mice expressing antisense RNA against the glucocorticoid receptor | Q48621659 |
| | Hypothalamic-pituitary-adrenocortical axis changes in a transgenic mouse with impaired glucocorticoid receptor function | Q48653410 |
| | Anti-sexual and anxiogenic behavioral consequences of corticotropin-releasing factor overexpression are centrally mediated | Q48711102 |
| | Tissue-specific and high-level expression of the human tyrosine hydroxylase gene in transgenic mice | Q48763835 |
| | The roles of steroidogenic factor 1 in endocrine development and function. | Q50537838 |
| | Targeted disruption of StAR provides novel insights into congenital adrenal hyperplasia. | Q50847920 |
| | Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress. | Q51081847 |
| | Adrenomedullary function is severely impaired in 21-hydroxylase-deficient mice. | Q51983721 |
| | Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice. | Q52165443 |
| | Behavioral responses to stress are intact in CRF-deficient mice. | Q52173697 |
| | Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: effects on T cell trafficking and T cell responsiveness during p | Q52206339 |
| | Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2. | Q52892360 |
| | Adrenal cortical activation in murine colitis | Q56933055 |
| | Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need | Q59059897 |
| | Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic | Q60308143 |
| | Viral gene delivery selectively restores feeding and prevents lethality of dopamine-deficient mice | Q64381642 |
| | Alteration of neurotransmitter phenotype in noradrenergic neurons of transgenic mice | Q67984006 |
| | Molecular and transgenic studies of the corticotropin-releasing hormone gene | Q70991802 |
| | Prenatal treatment and diagnosis of congenital adrenal hyperplasia owing to steroid 21-hydroxylase deficiency | Q71869573 |
| | Transgenic mice overexpressing the beta 1-adrenergic receptor in adipose tissue are resistant to obesity | Q71971210 |
| | Energy balance and lipid metabolism in transgenic mice bearing an antisense GCR gene construct | Q72860130 |
| | Induction of tyrosine hydroxylase protein and a transgene containing tyrosine hydroxylase 5' flanking sequences by stress in mouse adrenal gland | Q73107073 |
| | Immunosuppressive phenotype of corticotropin-releasing factor transgenic mice is reversed by adrenalectomy | Q73162259 |
| | Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase deficiency | Q73168559 |
| | Increased body fat mass and suppression of circulating leptin levels in response to hypersecretion of epinephrine in phenylethanolamine-N-methyltransferase (PNMT)-overexpressing mice | Q73218595 |
| | Impaired basal and restraint-induced epinephrine secretion in corticotropin-releasing hormone-deficient mice | Q73500711 |
| | Examining adrenergic roles in development, physiology, and behavior through targeted disruption of the mouse dopamine beta-hydroxylase gene | Q73780498 |
| | CRF type I receptor-deficient mice exhibit a pronounced pituitary-adrenal response to local inflammation | Q77932681 |
| | Steroidogenic acute regulatory protein | Q78017208 |
| P433 | issue | 3 | |
| P921 | main subject | gene targeting | Q211083 |
| | lessons learned | Q1673259 |
| P304 | page(s) | 275-287 | |
| P577 | publication date | 2001-08-01 | |
| P1433 | published in | Reviews in Endocrine and Metabolic Disorders | Q15766899 |
| P1476 | title | Lessons learned from gene targeting and transgenesis for adrenal physiology and disease | |
| P478 | volume | 2 | |