| P2093 | author name string | Müller U | |
| P2860 | cites work | Functional role of type I and type II interferons in antiviral defense | Q24276429 |
| | Targeted oncogene activation by site-specific recombination in transgenic mice | Q24564632 |
| | Ligand-activated site-specific recombination in mice | Q24600193 |
| | Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy | Q24603756 |
| | Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells | Q24616059 |
| | Targeted transgenesis | Q24631266 |
| | Establishment in culture of pluripotential cells from mouse embryos | Q27860625 |
| | Targeted mutation of the DNA methyltransferase gene results in embryonic lethality | Q28131773 |
| | Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination | Q28286762 |
| | Subregion- and cell type-restricted gene knockout in mouse brain | Q28300369 |
| | Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2 | Q28506189 |
| | Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype | Q28509173 |
| | Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background | Q57843811 |
| | Strain-dependent epithelial defects in mice lacking the EGF receptor | Q58326927 |
| | Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells | Q59064557 |
| | Targetted correction of a mutant HPRT gene in mouse embryonic stem cells | Q59085795 |
| | Mice, gene targeting and behaviour: more than just genetic background | Q64448518 |
| | Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop | Q67599796 |
| | Genomic DNA microextraction: A method to screen numerous samples | Q68210719 |
| | PCR-analyzed microsatellites for the inbred mouse strain 129/Sv, the strain most commonly used in gene knockout technology | Q71184181 |
| | Effects of genetic background on tumorigenesis in p53-deficient mice | Q71711400 |
| | Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments | Q72216655 |
| | Ligand-inducible and liver-specific target gene expression in transgenic mice | Q73137247 |
| | Transgenics on the Internet | Q73137271 |
| | Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy | Q73677664 |
| | Formation of germ-line chimeras from embryonic stem cells maintained with recombinant leukemia inhibitory factor | Q41720258 |
| | Inducible gene expression in the nervous system of transgenic mice | Q41733305 |
| | Chromosomal deletion complexes in mice by radiation of embryonic stem cells | Q42814312 |
| | Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Q43522858 |
| | Cre-mediated generation of a VCAM-1 null allele in transgenic mice | Q44928283 |
| | Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice | Q46046024 |
| | Spontaneous neurodegeneration in transgenic mice with mutant prion protein | Q46249938 |
| | Sustained somatic gene inactivation by viral transfer of Cre recombinase. | Q47948186 |
| | Efficient control of gene expression by single step integration of the tetracycline system in transgenic mice | Q47960978 |
| | Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression. | Q48053875 |
| | Long-term survival of the exon 10 insertional cystic fibrosis mutant mouse is a consequence of low level residual wild-type Cftr gene expression | Q48080544 |
| | Differences between inbred strains of mice in Morris water maze performance | Q48131097 |
| | Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions | Q48479400 |
| | Assessing the effects of the 129/Sv genetic background on swimming navigation learning in transgenic mutants: a study using mice with a modified beta-amyloid precursor protein gene | Q48542918 |
| | Hereditary covariations of neuronal circuitry and behavior: correlations between the proportions of hippocampal synaptic fields in the regio inferior and two-way avoidance in mice and rats | Q48810127 |
| | Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice | Q48963662 |
| | Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death | Q49116308 |
| | Site-specific integration of DNA into wild-type and mutant lox sites placed in the plant genome | Q49308730 |
| | Unusual behavioral phenotypes of inbred mouse strains. | Q51021041 |
| | Generation of Cre recombinase-specific monoclonal antibodies, able to characterize the pattern of Cre expression in cre-transgenic mouse strains. | Q52192102 |
| | Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice. | Q52196601 |
| | Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus. | Q52205977 |
| | Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice. | Q52214725 |
| | Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development. | Q52229612 |
| | Site-specific recombination between homologous chromosomes in Drosophila. | Q52448342 |
| | Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells. | Q52486323 |
| | Expression of prokaryotic genes for hygromycin B and G418 resistance as dominant-selection markers in mouse L cells | Q54468305 |
| | Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. | Q54558350 |
| | Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF | Q57198135 |
| | Bypass of lethality with mosaic mice generated by Cre– loxP -mediated recombination | Q57198343 |
| | Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies | Q57198382 |
| | Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice | Q28511888 |
| | Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene | Q28586800 |
| | Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein | Q28587017 |
| | Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice | Q28590025 |
| | Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1 | Q28592689 |
| | beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 |
| | Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene | Q28593669 |
| | Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin | Q28594189 |
| | Fate mapping of the mouse midbrain-hindbrain constriction using a site-specific recombination system | Q29400621 |
| | Efficient in vivo manipulation of mouse genomic sequences at the zygote stage | Q29547306 |
| | Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes | Q29547355 |
| | Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours | Q29547697 |
| | A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells | Q29614542 |
| | Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting | Q29614543 |
| | Inducible gene targeting in mice | Q29614544 |
| | Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells | Q29614545 |
| | An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination | Q29615355 |
| | Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice | Q29616222 |
| | Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells | Q29618298 |
| | Genetic dissection of complex traits | Q29618312 |
| | Control of memory formation through regulated expression of a CaMKII transgene | Q29619261 |
| | Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches | Q30454438 |
| | T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination | Q33645386 |
| | Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection | Q33927120 |
| | Cre-mediated site-specific translocation between nonhomologous mouse chromosomes | Q34050612 |
| | Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie | Q34250173 |
| | Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice | Q34263387 |
| | Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines | Q34267275 |
| | Chromosome engineering in mice | Q34290413 |
| | Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein | Q34294957 |
| | Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? | Q34390023 |
| | A humanized system for pharmacologic control of gene expression | Q34394730 |
| | Disruption of the mouse L1 gene leads to malformations of the nervous system | Q34444794 |
| | A novel strategy for the negative selection in mouse embryonic stem cells operated with immunotoxin-mediated cell targeting | Q34610611 |
| | Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter | Q34612904 |
| | Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments | Q34630211 |
| | Segmental genomic replacement by Cre-mediated recombination: genotoxic stress activation of the p53 promoter in single-copy transformants | Q34631906 |
| | Cre-mediated gene deletion in the mammary gland | Q34640577 |
| | Microinjection of cre recombinase RNA induces site-specific recombination of a transgene in mouse oocytes | Q34653658 |
| | Temporally and spatially regulated somatic mutagenesis in mice | Q34659147 |
| | Intra-chromosomal rearrangements generated by Cre-lox site-specific recombination | Q34737029 |
| | Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. | Q34819040 |
| | Establishment of a germ-line competent C57BL/6 embryonic stem cell line | Q34991986 |
| | Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors. | Q35512047 |
| | Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein | Q35823555 |
| | Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors | Q35844406 |
| | The origin and efficient derivation of embryonic stem cells in the mouse | Q36156785 |
| | Inducible gene expression and protein translocation using nontoxic ligands identified by a mammalian three-hybrid screen | Q36295125 |
| | Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice. | Q36645468 |
| | Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy | Q36668182 |
| | Long-range disruption of gene expression by a selectable marker cassette | Q36687936 |
| | Gene trapping and functional genomics | Q36881346 |
| | Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells | Q36958779 |
| | Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs | Q37045150 |
| | Single-copy transgenic mice with chosen-site integration | Q37384432 |
| | Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells | Q37576797 |
| | Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice | Q37577945 |
| | Diverse strategies for tetracycline-regulated inducible gene expression | Q37579022 |
| | Ecdysone-inducible gene expression in mammalian cells and transgenic mice. | Q37651825 |
| | Regulation of Cre recombinase activity by the synthetic steroid RU 486. | Q38359006 |
| | Inducible site-directed recombination in mouse embryonic stem cells | Q39715564 |
| | Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination | Q39717984 |
| | Targeted integration of DNA using mutant lox sites in embryonic stem cells | Q39719102 |
| | B lymphocyte-specific, Cre-mediated mutagenesis in mice | Q39719513 |
| | Cre-mediated somatic site-specific recombination in mice | Q39719850 |
| | Knockouts. Targeting the mouse genome: a compendium of knockouts (Part I) | Q40409394 |
| | Regulation of protein function through expression of chimaeric proteins | Q40535460 |
| | Reversed Genetics: A new Approach to the Elucidation of Structure-Function Relationship | Q40609139 |
| | The length of homology required for gene targeting in embryonic stem cells | Q40643090 |
| | Reexamination of Gene Targeting Frequency as a Function of the Extent of Homology between the Targeting Vector and the Target Locus | Q40655712 |
| | Site-specific recombinases: tools for genome engineering. | Q40721692 |
| | Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice | Q40896736 |
| | Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. | Q40981704 |
| | Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. | Q41064177 |
| | Selective ablation of differentiated cells permits isolation of embryonic stem cell lines from murine embryos with a non-permissive genetic background | Q41164390 |
| | Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor | Q41226239 |
| | Mouse models of human genetic disease: which mouse is more like a man? | Q41283188 |
| | Three-part inventions: intracellular signaling and induced proximity | Q41297022 |
| | Double replacement gene targeting for the production of a series of mouse strains with different prion protein gene alterations | Q41298105 |
| | A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination. | Q41352964 |
| | Insertion of a targeting construct in a Hoxd-10 allele can influence the control of Hoxd-9 expression | Q41419024 |
| | Selective disruption of genes expressed in totipotent embryonal stem cells | Q41623128 |
| | A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung | Q41625618 |
| P433 | issue | 1-2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | gene targeting | Q211083 |
| | phenotype | Q104053 |
| P304 | page(s) | 3-21 | |
| P577 | publication date | 1999-04-01 | |
| P1433 | published in | Mechanisms of Development | Q6804657 |
| P1476 | title | Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis | |
| P478 | volume | 82 | |