Gene repair in the new age of gene therapy

scientific article

Gene repair in the new age of gene therapy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1053/JHEP.2002.32421
P698PubMed publication ID11870362

P50authorClifford J SteerQ114401691
Betsy T KrenQ114401697
P2093author name stringPaul D Richardson
P2860cites workViral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeuticsQ28141424
Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplastyQ30661436
Triplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51.Q30661706
Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotideQ30671185
Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathwayQ30831983
Gene repair using chimeric RNA/DNA oligonucleotidesQ33647685
Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysisQ33650414
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Liver-directed gene therapy: promises, problems and prospects at the turn of the centuryQ33870289
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Nonviral vectors in the new millennium: delivery barriers in gene transferQ34270234
Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotideQ35620922
Transfection and homologous recombination involving single-stranded DNA substrates in mammalian cells and nuclear extractsQ37392520
Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotideQ37709530
Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides.Q38297805
The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extractsQ38307086
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Repairing the sickle cell mutation. I. Specific covalent binding of a photoreactive third strand to the mutated base pairQ38322549
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Bone marrow as a potential source of hepatic oval cellsQ38501137
In vivo gene repair of point and frameshift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotidesQ39228801
A search for base analogs to enhance third-strand binding to 'inverted' target base pairs of triplexes in the pyrimidine/parallel motifQ39729708
Targeted correction of the point mutations of beta-thalassemia and targeted mutagenesis of the nucleotide associated with HPFH by RNA/DNA oligonucleotides: potential for beta-thalassemia gene therapyQ40786923
Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotideQ40988083
Targeted replacement of normal and mutant CFTR sequences in human airway epithelial cells using DNA fragmentsQ40995313
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon systemQ41734970
Short DNA fragments induce site specific recombination in mammalian cellsQ41744217
Therapeutic gene targetingQ41760437
Intracellular pH regulation and Na+/H+ exchange activity in human hepatic stellate cells: effect of platelet-derived growth factor, insulin-like growth factor 1 and insulinQ43588112
Expression of DeltaF508 CFTR in normal mouse lung after site-specific modification of CFTR sequences by SFHR.Q43653608
Mitochondria isolated from liver contain the essential factors required for RNA/DNA oligonucleotide-targeted gene repairQ43667782
Direct immunization of malaria DNA vaccine into the liver by gene gun protects against lethal challenge of Plasmodium berghei sporozoiteQ44143012
Introduction of single base substitutions at homologous chromosomal sequences by adeno-associated virus vectorsQ45737647
Targeted gene correction by small single-stranded oligonucleotides in mammalian cellsQ45876530
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectgene therapyQ213901
P304page(s)512-518
P577publication date2002-03-01
P1433published inHepatologyQ15724398
P1476titleGene repair in the new age of gene therapy
P478volume35