Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma

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Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...746117H
P356DOI10.1371/JOURNAL.PONE.0046117
P932PMC publication ID3462182
P698PubMed publication ID23049692
P5875ResearchGate publication ID232226789

P50authorErlend B. SmelandQ17107612
Kanutte HuseQ64788710
June H. MyklebustQ76432340
Morten P OksvoldQ125351238
Sébastien WälchliQ41631179
Knut LiestølQ45381873
P2093author name stringAsh A Alizadeh
Lise Forfang
Maren Bakkebø
May L Bredahl
Vera I Hilden
P2860cites workSmad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formationQ24302554
SMAD6 contributes to patient survival in non-small cell lung cancer and its knockdown reestablishes TGF-beta homeostasis in lung cancer cellsQ24319956
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip dataQ24537656
Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesisQ24624863
Coordinated expression of microRNA-155 and predicted target genes in diffuse large B-cell lymphomaQ24648226
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1Q24806130
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphomaQ27824784
Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosisQ28139074
The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancerQ28145081
Bone morphogenetic protein (BMP)-2 induces apoptosis in human myeloma cellsQ28217103
Escaping from the TGFbeta anti-proliferative controlQ28240031
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolismQ29617479
BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomasQ29622911
Reverse engineering of regulatory networks in human B cellsQ30004211
Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7.Q50993571
Decreased expression of bone morphogenetic protein (BMP) receptor type II correlates with insensitivity to BMP-6 in human renal cell carcinoma cells.Q53908639
Balancing BMP Signaling through Integrated Inputs into the Smad1 LinkerQ60325056
Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cellsQ73387924
Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell developmentQ80139081
MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomasQ81418207
PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including BCL-6, CD10, CD20 and CD22: identification of PU.1 putative binding sites in the BCL-6 promotorQ81744830
Involvement of twisted gastrulation in T cell-independent plasma cell productionQ84102328
Aggressive melanoma cells escape from BMP7-mediated autocrine growth inhibition through coordinated Noggin upregulation.Q30487367
Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesisQ33748979
TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPKQ33752152
B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progressionQ34059352
The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancersQ34777913
IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosisQ34790518
Tgf-beta superfamily signaling in embryonic development and homeostasisQ34963093
Transforming growth factor-beta signaling in normal and malignant hematopoiesisQ35217394
Controlling cell fate by bone morphogenetic protein receptors.Q35600636
Resistance to TGF-beta 1 correlates with aberrant expression of TGF-beta receptor II in human B-cell lymphoma cell linesQ35839895
Alterations in components of the TGF-beta superfamily signaling pathways in human cancerQ36323395
Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cellsQ36368023
Role of bone morphogenetic proteins in transitional cell carcinoma cellsQ36405736
Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in miceQ36421055
A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patientsQ37381683
The emerging role of TGF-beta superfamily coreceptors in cancer.Q37553118
Recent advances in BMP receptor signalingQ37629355
Bone morphogenetic proteins and cancer: review of the literatureQ37665275
Bone Morphogenetic Proteins: A critical reviewQ37801468
Restoration of bone morphogenetic protein receptor type II expression leads to a decreased rate of tumor growth in bladder transitional cell carcinoma cell line TSU-Pr1.Q38445560
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC.Q39469388
Promoter hypermethylation of the bone morphogenetic protein-6 gene in malignant lymphoma.Q40118425
BMP-6 inhibits human bone marrow B lymphopoiesis--upregulation of Id1 and Id3.Q40329682
Bone morphogenetic protein 2 stimulation of tumor growth involves the activation of Smad-1/5.Q40358308
Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cellsQ40518052
Bone morphogenetic protein-5, -6 and -7 inhibit growth and induce apoptosis in human myeloma cellsQ40604725
Growth regulation of human prostate cancer cells by bone morphogenetic protein-2.Q41078790
Differentiation and apoptosis of human germinal center B-lymphocytesQ41522446
Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancerQ41610166
Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genesQ43238530
Prognostic significance of the expression of Smad4 and Smad7 in human gastric carcinomasQ44434503
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectB-cell lymphomaQ4833719
P304page(s)e46117
P577publication date2012-10-01
P1433published inPLOS OneQ564954
P1476titleRole of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma
P478volume7

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cites work (P2860)
Q49843417Artesunate shows potent anti-tumor activity in B-cell lymphoma
Q33657811BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5
Q28533353BMP7 expression correlates with secondary drug resistance in mantle cell lymphoma
Q40993075Bone Regeneration Using Bone Morphogenetic Proteins and Various Biomaterial Carriers
Q38588911Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
Q48108703Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell lymphoma patients treated with rituximab-CHOP.
Q41048773DNA methylation profiling reveals common signatures of tumorigenesis and defines epigenetic prognostic subtypes of canine Diffuse Large B-cell Lymphoma.
Q42503470Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling
Q36472101Effect of alendronate sodium on the expression of mesenchymal-epithelial transition markers in mice with liver fibrosis
Q37429726MicroRNA-155 controls RB phosphorylation in normal and malignant B lymphocytes via the noncanonical TGF-β1/SMAD5 signaling module
Q38220764SMAD7: a timer of tumor progression targeting TGF-β signaling

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