scholarly article | Q13442814 |
P819 | ADS bibcode | 2012PLoSO...746720L |
P356 | DOI | 10.1371/JOURNAL.PONE.0046720 |
P8608 | Fatcat ID | release_jqiiw2mjujehdjjwentx6gs32a |
P953 | full work available online at | https://europepmc.org/articles/PMC3463541 |
https://europepmc.org/articles/PMC3463541?pdf=render | ||
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0046720&type=printable | ||
P932 | PMC publication ID | 3463541 |
P698 | PubMed publication ID | 23056421 |
P5875 | ResearchGate publication ID | 232233010 |
P2093 | author name string | Hua Zhang | |
Jian Xu | |||
Hongtao Liu | |||
Shujie Yu | |||
P2860 | cites work | Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes | Q23757358 |
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy | Q24316492 | ||
AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice | Q24318212 | ||
Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation | Q24323121 | ||
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis | Q24564718 | ||
Nitric oxide and peroxynitrite in health and disease | Q24645400 | ||
VEGF signaling inside vascular endothelial cells and beyond | Q27687815 | ||
Autophagy in the Pathogenesis of Disease | Q27860558 | ||
Identification of a new endothelial cell growth factor receptor tyrosine kinase | Q28117368 | ||
Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation | Q28187673 | ||
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1 | Q28300820 | ||
Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid: role of NAD(P)H oxidase-derived superoxide and peroxynitrite | Q52574107 | ||
The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling | Q52845770 | ||
Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus | Q53536180 | ||
Diminished penile expression of vascular endothelial growth factor and its receptors at the insulin-resistant stage of a type II diabetic rat model: a possible cause for erectile dysfunction in diabetes | Q53909177 | ||
Differential modulation of angiogenesis by advanced glycation end products | Q54627319 | ||
Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease | Q54645803 | ||
VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment | Q58035861 | ||
Inhibition of glyoxalase I by various clinically used anticancer drugs | Q68336483 | ||
Glucose-induced inhibition of angiogenesis in the rat sponge granuloma is prevented by aminoguanidine | Q74589833 | ||
Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue | Q77531118 | ||
Role of oxidative stress in diabetic complications: a new perspective on an old paradigm | Q77804864 | ||
Autophagy and angiogenesis inhibition | Q80647665 | ||
Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1 | Q81152929 | ||
Angiogenesis, arteriogenesis, and diabetes: paradigm reassessed? | Q81154894 | ||
Soluble CD146 displays angiogenic properties and promotes neovascularization in experimental hind-limb ischemia | Q83038813 | ||
Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro | Q37097071 | ||
Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications | Q37107174 | ||
Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells | Q37325249 | ||
VEGF resistance as a molecular basis to explain the angiogenesis paradox in diabetes mellitus. | Q37631627 | ||
Autophagy in vascular disease | Q37693522 | ||
Trends in advanced glycation end products research in diabetes mellitus and its complications. | Q37716694 | ||
Glyoxalase in diabetes, obesity and related disorders | Q37844971 | ||
Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes | Q37858162 | ||
Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis. | Q39780346 | ||
Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells | Q40175799 | ||
Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells | Q42134556 | ||
Autophagy: a sweet process in diabetes | Q42442804 | ||
MicroRNA and mechanisms of impaired angiogenesis in diabetes mellitus | Q42922925 | ||
More sugar, less blood vessels: another piece in the puzzle of increased cardiovascular risk in diabetes | Q43004192 | ||
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis | Q43072819 | ||
Impaired gastric ulcer healing in diabetic mice: role of methylglyoxal. | Q43100893 | ||
Glyoxalase I deficiency is associated with an unusual level of advanced glycation end products in a hemodialysis patient | Q43818249 | ||
Adverse effects of dietary glycotoxins on wound healing in genetically diabetic mice | Q44631836 | ||
Methotrexate inhibits the glyoxalase system in vivo in children with acute lymphoid leukaemia | Q45083105 | ||
Endothelial cell confluence regulates cyclooxygenase-2 and prostaglandin E2 production that modulate motility. | Q45107794 | ||
Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells | Q46176333 | ||
AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress | Q47858200 | ||
VEGFR2 expression and TGF-β signaling in initial and recurrent high-grade human glioma | Q48853324 | ||
The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts | Q28565683 | ||
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice | Q28593600 | ||
The role of autophagy during the early neonatal starvation period | Q29547489 | ||
Angiogenesis in life, disease and medicine | Q29614539 | ||
Oxidative Stress and Diabetic Complications | Q29615423 | ||
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics | Q29615424 | ||
VEGF receptor signalling - in control of vascular function | Q29617256 | ||
Endothelial cell migration on fibronectin is regulated by syntaxin 6-mediated alpha5beta1 integrin recycling | Q30424470 | ||
Systems biology of vascular endothelial growth factors | Q30438979 | ||
Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice | Q31146191 | ||
Vascular endothelial growth factor and diabetes: the agonist versus antagonist paradox | Q33747359 | ||
Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications | Q33793764 | ||
Preventing local regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 enhances angiogenesis | Q33922773 | ||
Therapeutic targeting of mitochondrial superoxide in hypertension | Q33981734 | ||
Molecular insights and therapeutic targets for diabetic endothelial dysfunction | Q34022332 | ||
Tyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension | Q34022338 | ||
VEGFR2 translocates to the nucleus to regulate its own transcription | Q34043465 | ||
Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol. | Q34451462 | ||
VEGF Receptor Signal Transduction | Q34461939 | ||
Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats | Q34489018 | ||
Regulation of vascular endothelial growth factor receptor 2 trafficking and angiogenesis by Golgi localized t-SNARE syntaxin 6 | Q34666953 | ||
Coupling In vitro and In vivo Paradigm Reveals a Dose Dependent Inhibition of Angiogenesis Followed by Initiation of Autophagy by C6-Ceramide | Q35022529 | ||
Abnormal angiogenesis in diabetes mellitus | Q35033890 | ||
Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis | Q35146041 | ||
Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ3 | Q35172515 | ||
Increased VEGFR2 expression during human late endothelial progenitor cells expansion enhances in vitro angiogenesis with up-regulation of integrin alpha(6) | Q35459633 | ||
Structural variation in bacterial glyoxalase I enzymes: investigation of the metalloenzyme glyoxalase I from Clostridium acetobutylicum. | Q35516038 | ||
Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats | Q35594338 | ||
The Antifungal Drug Itraconazole Inhibits Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Glycosylation, Trafficking, and Signaling in Endothelial Cells | Q35626139 | ||
The emerging role of autophagy in the pathophysiology of diabetes mellitus | Q35985421 | ||
Hydrogen peroxide regulation of endothelial function: origins, mechanisms, and consequences | Q36189782 | ||
Receptor for advanced glycation end products and its ligands: a journey from the complications of diabetes to its pathogenesis | Q36203962 | ||
Endothelial cells and VEGF in vascular development | Q36342350 | ||
Vascular endothelial growth factor (VEGF)-Receptor2: its biological functions, major signaling pathway, and specific ligand VEGF-E. | Q36489757 | ||
Is mitochondrial generation of reactive oxygen species a trigger for autophagy? | Q37038318 | ||
Receptor for advanced glycation end products (RAGE): a novel therapeutic target for diabetic vascular complication | Q37090274 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | angiogenesis | Q539568 |
endothelium | Q111140 | ||
autophagy | Q288322 | ||
P304 | page(s) | e46720 | |
P577 | publication date | 2012-10-03 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2 | |
Angiogenesis Impairment in Diabetes: Role of Methylglyoxal-Induced Receptor for Advanced Glycation Endproducts, Autophagy and Vascular Endothelial Growth Factor Receptor 2 | |||
P478 | volume | 7 |
Q46554485 | Autophagy is involved in regulating VEGF during high-glucose-induced podocyte injury |
Q37577446 | Autophagy triggered by magnolol derivative negatively regulates angiogenesis |
Q35484237 | Autophagy: an emerging therapeutic target in vascular diseases |
Q38108973 | Cellular metabolic and autophagic pathways: traffic control by redox signaling |
Q48512258 | Chamaejasmine B Induces the Anergy of Vascular Endothelial Cells to VEGFA Pro-angiogenic Signal by Autophagic Regulation of VEGFR2 in Breast Cancer |
Q37349166 | Chitosan oligosaccharides block LPS-induced O-GlcNAcylation of NF-κB and endothelial inflammatory response |
Q89552373 | Dicarbonyl Stress and S-Glutathionylation in Cerebrovascular Diseases: A Focus on Cerebral Cavernous Malformations |
Q92084106 | Dicarbonyl Stress at the Crossroads of Healthy and Unhealthy Aging |
Q58590553 | Distinct role of autophagy on angiogenesis: highlights on the effect of autophagy in endothelial lineage and progenitor cells |
Q28533889 | Edaravone protected human brain microvascular endothelial cells from methylglyoxal-induced injury by inhibiting AGEs/RAGE/oxidative stress |
Q55177951 | Effects of IMOD™ on angiogenesis, miR-503 and CDC25 expression levels in heart tissue of diabetic male rats. |
Q42511108 | Endothelial mechanotransduction proteins and vascular function are altered by dietary sucrose supplementation in healthy young male subjects |
Q55014759 | Expert curation for building network-based dynamical models: a case study on atherosclerotic plaque formation. |
Q45736800 | Global profiling of carbonyl metabolites with a photo-cleavable isobaric labeling affinity tag. |
Q36050933 | Glyoxalase-1 overexpression partially prevents diabetes-induced impaired arteriogenesis in a rat hindlimb ligation model |
Q34664366 | Human immunodeficiency virus-1 (HIV-1)-mediated apoptosis: new therapeutic targets |
Q37428793 | Identification of autophagy as a longevity-assurance mechanism in the aging model Podospora anserina |
Q57110548 | Immunomodulation by Processed Animal Feed: The Role of Maillard Reaction Products and Advanced Glycation End-Products (AGEs) |
Q38210860 | Impaired proteostasis: role in the pathogenesis of diabetes mellitus |
Q93088955 | Inhibition of Glyoxalase-I Leads to Reduced Proliferation, Migration and Colony Formation, and Enhanced Susceptibility to Sorafenib in Hepatocellular Carcinoma |
Q47779685 | Methylglyoxal attenuates insulin signaling and downregulates the enzymes involved in cholesterol biosynthesis |
Q38956425 | Methylglyoxal in Metabolic Disorders: Facts, Myths, and Promises |
Q37631669 | Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage. |
Q48181868 | Methylglyoxal-Induced Protection Response and Toxicity: Role of Glutathione Reductase and Thioredoxin Systems. |
Q38864127 | Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells |
Q33687365 | Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance. |
Q95936565 | Molecular mechanisms of methylglyoxal-induced aortic endothelial dysfunction in human vascular endothelial cells |
Q35686549 | Penicillium chrysogenum as a model system for studying cellular effects of methylglyoxal. |
Q39381435 | Perpetual change: autophagy, the endothelium, and response to vascular injury |
Q33645471 | Podocyte Autophagy: A Potential Therapeutic Target to Prevent the Progression of Diabetic Nephropathy |
Q34048268 | Proteasomal degradation of O-GlcNAc transferase elevates hypoxia-induced vascular endothelial inflammatory response†. |
Q37021145 | Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling |
Q92462391 | The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome - a transcriptomic and proteomic approach |
Q57470205 | Tricyclic antidepressant amitriptyline inhibits autophagic flux and prevents tube formation in vascular endothelial cells |
Q34777068 | Upregulation of Unc-51-like kinase 1 by nitric oxide stabilizes SIRT1, independent of autophagy. |
Q90308406 | VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPKα1 |
Q47145612 | VEGFR2 alteration in Alzheimer's disease |
Q37636453 | Vascular effects of advanced glycation endproducts: Clinical effects and molecular mechanisms |
Search more.