Apolipoprotein C2

mammalian protein found in Homo sapiens

Apolipoprotein C2 is …
instance of (P31):
proteinQ8054

External links are
P705Ensembl protein IDENSP00000252490
ENSP00000465001
ENSP00000466775
ENSP00000476835
ENSP00000477261
P638PDB structure ID1BY6
1I5J
1O8T
1SOH
P637RefSeq protein IDNP_000474
P10376ScienceDirect topic IDagricultural-and-biological-sciences/apolipoprotein-c-ii
P352UniProt protein IDP02655

P682biological processlipid metabolismQ2792936
reverse cholesterol transportQ7318217
positive regulation of phospholipid catabolic processQ14916271
chylomicron assemblyQ21123773
lipid catabolic processQ14762268
retinoid metabolic processQ14859548
positive regulation of fatty acid biosynthetic processQ14859629
lipoprotein transportQ14864559
chylomicron remodelingQ14864751
very-low-density lipoprotein particle remodelingQ14864752
triglyceride homeostasisQ14864754
negative regulation of receptor-mediated endocytosisQ14865048
cholesterol homeostasisQ14872722
lipid transportQ14872727
negative regulation of catalytic activityQ14873900
high-density lipoprotein particle remodelingQ14878188
cholesterol effluxQ14890389
phospholipid effluxQ14890392
chylomicron remnant clearanceQ14890403
high-density lipoprotein particle clearanceQ14890408
negative regulation of very-low-density lipoprotein particle clearanceQ14904544
negative regulation of cholesterol transportQ14904546
negative regulation of lipid metabolic processQ14904548
positive regulation of lipoprotein lipase activityQ14910995
positive regulation of phospholipase activityQ14911623
positive regulation of triglyceride catabolic processQ14916268
positive regulation of very-low-density lipoprotein particle remodelingQ14916269
triglyceride-rich lipoprotein particle remodelingQ14916270
P681cell componentchylomicronQ423126
extracellular spaceQ1385443
extracellular regionQ14645596
early endosomeQ14860538
very-low-density lipoprotein particleQ14864742
spherical high-density lipoprotein particleQ14864928
low-density lipoprotein particleQ14872701
high-density lipoprotein particleQ14878180
intermediate-density lipoprotein particleQ14890304
P702encoded byAPOC2Q14916272
P703found in taxonHomo sapiensQ15978631
P680molecular functionlipid bindingQ14358833
protein homodimerization activityQ14762996
phospholipase bindingQ14860858
enzyme activator activityQ14878167
phospholipase activator activityQ14891353
lipase inhibitor activityQ14904537
lipoprotein lipase activator activityQ14910979
P361part ofapolipoprotein C-IIQ24723057
ApoC-II domain superfamilyQ54455163

Reverse relations

has part(s) (P527)
Q50274733APOA4,APOA5,APOC2,CIDEC,FGF21 [cytosol]
Q50266487CR [early endosome]
Q50266475CR [extracellular region]
Q100162885Expression of APOC2 regulated by NR1H2 or NR1H3
Q50299765Spherical HDL binds C and E apolipoproteins
Q50274739TG-depleted chylomicron [extracellular region]
Q50299756chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols
Q50274715chylomicron [extracellular region]
Q50266470mature CM:atREs [extracellular region]
Q50274740spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III [extracellular region]
Q50266467spherical HDL:apoC-II:apoC-III:apoE [extracellular region]

main subject (P921)
Q24339431Activation of lipoprotein lipase by native and synthetic fragments of human plasma apolipoprotein C-II
Q24301565Apolipoprotein A-V-heparin interactions: implications for plasma lipoprotein metabolism
Q22253363Apolipoprotein C-II39-62 activates lipoprotein lipase by direct lipid-independent binding
Q24290771Apolipoprotein specificity for lipid efflux by the human ABCAI transporter
Q24298495Apolipoproteins C-II and C-III inhibit selective uptake of low- and high-density lipoprotein cholesteryl esters in HepG2 cells
Q24310834Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase
Q24299052Fractionation of cholesteryl ester rich intermediate density lipoprotein subpopulations by chondroitin sulphate
Q24320060Identification of disulfide-linked apolipoprotein species in human lipoproteins
Q24300330Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver
Q24336276Isolation and characterization of human apolipoprotein M-containing lipoproteins
Q24323234Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway
Q24305538Reduction of plasma triglycerides in apolipoprotein C-II transgenic mice overexpressing lipoprotein lipase in muscle

Q14916272APOC2encodesP688

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