Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney diseas

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Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney diseas is …
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scholarly articleQ13442814

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P356DOI10.1002/EJHF.218
P698PubMed publication ID25678098

P50authorFaiez ZannadQ19631268
Piotr PonikowskiQ22114836
Stefan D. AnkerQ30310195
Henry KrumQ82083581
Adriaan A VoorsQ91537232
Christina NowackQ114291637
Alexander PieperQ114291639
Nina Kimmeskamp-KirschbaumQ114291640
Lars KøberQ33310611
Aldo P. MaggioniQ40310748
Mihai GheorghiadeQ60059386
Bertram PittQ63107334
Gerasimos FilippatosQ63107352
P2093author name stringMichael Böhm
So-Young Kim
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Prognostic value of changes in N-terminal pro-brain natriuretic peptide in Val-HeFT (Valsartan Heart Failure Trial)Q81955371
Finerenone, a novel selective nonsteroidal mineralocorticoid receptor antagonist protects from rat cardiorenal injuryQ87428114
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Critical elements of clinical follow-up after hospital discharge for heart failure: insights from the EVEREST trialQ37066197
Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trialQ37094366
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Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trialQ38454911
Prognosis and response to therapy of first inpatient and outpatient heart failure event in a heart failure clinical trial: MADIT-CRT.Q39243083
N-terminal-pro-brain natriuretic peptide predicts outcome after hospital discharge in heart failure patients.Q40479579
PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathyQ42672479
Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseasesQ42716993
Effect of eplerenone versus spironolactone on cortisol and hemoglobin A₁(c) levels in patients with chronic heart failureQ42795421
Effect of spironolactone on left ventricular systolic and diastolic function in patients with early stage chronic kidney diseaseQ42830307
Randomized, double-blind, multicenter, placebo-controlled study evaluating the effect of aldosterone antagonism with eplerenone on ventricular remodeling in patients with mild-to-moderate heart failure and left ventricular systolic dysfunctionQ43124593
Serum cortisol as a useful predictor of cardiac events in patients with chronic heart failure: the impact of oxidative stressQ43240308
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Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failureQ43573505
Hospitalizations for heart failure in the United States--a sign of hopeQ43599944
Effects of valsartan on morbidity and mortality in patients with heart failure not receiving angiotensin-converting enzyme inhibitorsQ44188982
Eplerenone in patients with systolic heart failure and mild symptomsQ44272913
Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation StudyQ44485270
Improving postdischarge outcomes in patients hospitalized for acute heart failure syndromesQ44657274
Prognostic impact of plasma N-terminal pro-brain natriuretic peptide in severe chronic congestive heart failure: a substudy of the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trialQ45069603
Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure: insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival StuQ46034385
EURObservational Research Programme: regional differences and 1-year follow-up results of the Heart Failure Pilot Survey (ESC-HF Pilot).Q46275793
EURObservational Research Programme: the Heart Failure Pilot Survey (ESC-HF Pilot).Q46414626
Carvedilol therapy is associated with a sustained decline in brain natriuretic peptide levels in patients with congestive heart failureQ46466518
Early and sustained effects of cardiac resynchronization therapy on N-terminal pro-B-type natriuretic peptide in patients with moderate to severe heart failure and cardiac dyssynchronyQ48273698
Serial NT-proBNP monitoring and outcomes in outpatients with decompensation of heart failureQ48335466
Effects of aldosterone receptor blockade in patients with mild-moderate heart failure taking a beta-blockerQ48358493
Safety and Efficacy of Eplerenone in Patients at High Risk for Hyperkalemia and/or Worsening Renal FunctionQ57396191
Acute heart failure in the emergency department: Short and long-term outcomes of elderly patients with heart failureQ57483731
Update on Aldosterone Antagonists Use in Heart Failure With Reduced Left Ventricular Ejection Fraction Heart Failure Society of America Guidelines CommitteeQ59637921
Usefulness of clinical and NT-proBNP monitoring for prognostic guidance in destabilized heart failure outpatientsQ60619537
P433issue2
P921main subjectheart failureQ181754
chronic heart failureQ11829287
P304page(s)224-232
P577publication date2015-02-01
P1433published inEuropean Journal of Heart FailureQ5017954
P1476titleRationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney diseas
P478volume17

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