Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7

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Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7 is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...747067K
P356DOI10.1371/JOURNAL.PONE.0047067
P932PMC publication ID3480380
P698PubMed publication ID23115635
P5875ResearchGate publication ID232746183

P50authorFelicity C. KalinowskiQ55294173
P2093author name stringPeter J Leedman
Alishum Ali
Clarissa Ganda
Keith M Giles
Michael R Epis
Patrick A Candy
Rebecca J Webster
P2860cites workA new human cell line (FaDu) from a hypopharyngeal carcinoma.Q52829962
microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling.Q54364560
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Low-level expression of microRNAs let-7d and miR-205 are prognostic markers of head and neck squamous cell carcinomaQ24646667
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancerQ26852215
Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas.Q27851397
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastomaQ28280337
MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functionsQ28297593
Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7Q28303603
CK2 binds, phosphorylates, and regulates its pivotal substrate Cdc37, an Hsp90-cochaperoneQ28581892
The phosphatidylinositol 3-Kinase AKT pathway in human cancerQ29547860
Gene silencing by microRNAs: contributions of translational repression and mRNA decayQ29615825
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neckQ29619277
Usp18 regulates epidermal growth factor (EGF) receptor expression and cancer cell survival via microRNA-7.Q30425986
miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathwaysQ30428483
VASCo: computation and visualization of annotated protein surface contacts.Q30486213
The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinomaQ30494514
Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of TongueQ33331288
Platinum-based chemotherapy plus cetuximab in head and neck cancerQ33381094
Predicting microRNA targets in time-series microarray experiments via functional data analysisQ33407825
A PCR primer bank for quantitative gene expression analysisQ33447710
Preparation of pure cell cultures by cloningQ33888007
AKT plays a central role in tumorigenesisQ33944165
Understanding resistance to EGFR inhibitors-impact on future treatment strategiesQ34088424
TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancerQ34100276
Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neckQ34287207
MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expressionQ34372477
MicroRNAs and endocrine biologyQ34486152
Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neckQ34533587
Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancerQ34635861
Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancerQ34816422
MicroRNA alterations in head and neck squamous cell carcinoma.Q35253630
The RNA-binding protein HuR opposes the repression of ERBB-2 gene expression by microRNA miR-331-3p in prostate cancer cellsQ35842164
Present and Future of EGFR Inhibitors for Head and Neck Squamous Cell CancerQ35875753
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive reviewQ36037933
Ten human carcinoma cell lines derived from squamous carcinomas of the head and neckQ36045386
Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitionsQ37072581
New promising molecular targets in head and neck squamous cell carcinomaQ37983463
MicroRNA expression profiles in head and neck cancer cell linesQ38302158
The role of serum response factor in hepatocellular carcinoma: Implications for disease progressionQ38482033
Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cellsQ39386176
Both mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinases (ERK) 1/2 and phosphatidylinositide-3-OH kinase (PI3K)/Akt pathways regulate activation of E-twenty-six (ETS)-like transcription factor 1 (Elk-1) in U138 glioblastomQ39442732
Liposomal delivery of MicroRNA-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cellsQ39516392
MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer CellsQ39646854
Identification of biomarkers in human head and neck tumor cell lines that predict for in vitro sensitivity to gefitinibQ39707468
Response to trastuzumab, erlotinib, and bevacizumab, alone and in combination, is correlated with the level of human epidermal growth factor receptor-2 expression in human breast cancer cell linesQ40067422
Protein kinase CK2 phosphorylates and upregulates Akt/PKB.Q40437202
Deregulated cyclin D1 expression is associated with decreased efficacy of the selective epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in head and neck squamous cell carcinoma cell linesQ40486711
The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cellsQ40527345
The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo.Q40685410
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cellsQ40895491
Differences in EGF related radiosensitisation of human squamous carcinoma cells with high and low numbers of EGF receptorsQ41161192
Signal transduction through MAP kinase cascadesQ41750250
Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells.Q42498478
Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomasQ42801605
Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatmentsQ43719931
Determination of subcutaneous tumor size in athymic (nude) miceQ46296687
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjecterlotinibQ418369
head and neck cancerQ1783924
head and neck carcinomaQ18554836
neck cancerQ18966654
P304page(s)e47067
P577publication date2012-10-24
P1433published inPLOS OneQ564954
P1476titleRegulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7
P478volume7

Reverse relations

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