Adipocyte dysfunction in a mouse model of polycystic ovary syndrome (PCOS): evidence of adipocyte hypertrophy and tissue-specific inflammation

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Adipocyte dysfunction in a mouse model of polycystic ovary syndrome (PCOS): evidence of adipocyte hypertrophy and tissue-specific inflammation is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...748643M
P356DOI10.1371/JOURNAL.PONE.0048643
P932PMC publication ID3485364
P698PubMed publication ID23119079
P5875ResearchGate publication ID232766863

P50authorJennifer HillQ56223776
Joseph S MarinoQ59679576
P2093author name stringJens C Bruning
Abigail R Dowling
Jeffrey Iler
Roberto Coppari
Streamson Chua
P2860cites workInflammation and insulin resistanceQ22241893
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A very large proportion of young Danish women have polycystic ovaries: is a revision of the Rotterdam criteria needed?Q50552153
Ultrasonographic extended-view technique for evaluation of abdominal fat distribution in lean women with polycystic ovary syndrome.Q51049449
Comparison of MRI-assessed body fat content between lean women with polycystic ovary syndrome (PCOS) and matched controls: less visceral fat with PCOS.Q51377041
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Risk of gestational diabetes mellitus in women with polycystic ovary syndrome: a systematic review and a meta-analysisQ34810149
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Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposureQ35055467
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siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscleQ36807616
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Interleukin-6: an autocrine regulator of the mouse cumulus cell-oocyte complex expansion processQ37244699
Reduced adaptation of the pancreatic B cells during pregnancy is the major causal factor for gestational diabetes: current knowledge and metabolic effects on the offspringQ37291071
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Metabolic features of the reproductive phenotypes of polycystic ovary syndrome.Q37412812
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Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanismsQ40391481
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The subcutaneous abdominal fat and not the intraabdominal fat compartment is associated with anovulation in women with obesity and infertility.Q43143743
Depot-specific differences in adipogenic progenitor abundance and proliferative response to high-fat dietQ43297876
Low grade chronic inflammation in women with polycystic ovarian syndromeQ43633815
Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome.Q43723378
The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat.Q43925591
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectadipocyteQ357519
polycystic ovary syndromeQ500816
inflammationQ101991
polycystic ovaryQ5547896
P304page(s)e48643
P577publication date2012-10-31
P1433published inPLOS OneQ564954
P1476titleAdipocyte dysfunction in a mouse model of polycystic ovary syndrome (PCOS): evidence of adipocyte hypertrophy and tissue-specific inflammation
P478volume7

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cites work (P2860)
Q92519089Animal Models for Human Polycystic Ovary Syndrome (PCOS) Focused on the Use of Indirect Hormonal Perturbations: A Review of the Literature
Q26745164Genetic Rodent Models of Obesity-Associated Ovarian Dysfunction and Subfertility: Insights into Polycystic Ovary Syndrome
Q51122360High-fat diet induces significant metabolic disorders in a mouse model of polycystic ovary syndrome.
Q35810003Impact of Treatment with Metformin on Adipocytokines in Patients with Polycystic Ovary Syndrome: A Meta-Analysis
Q39102072Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms
Q90494218Physical Exercise following bariatric surgery in women with Morbid obesity: Study protocol clinical trial (SPIRIT compliant)
Q87847396Prenatal androgen exposure causes hypertension and gut microbiota dysbiosis
Q37268584Prevalence of polycystic ovary syndrome in adolescents.
Q47133443The Effect of Curcumin on TNF-α, IL-6 and CRP Expression in a Model of Polycystic Ovary Syndrome as an Inflammation State
Q49971668The Role of Sex and Sex Hormones in Regulating Obesity-Induced Inflammation
Q50143831The relationship between IL-18 and atherosclerotic cardiovascular risk in Egyptian lean women with polycystic ovary syndrome
Q37167978Up-regulation of miR-21 and 146a expression and increased DNA damage frequency in a mouse model of polycystic ovary syndrome (PCOS)

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