Ribosomal proteins: functions beyond the ribosome

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Ribosomal proteins: functions beyond the ribosome is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1093/JMCB/MJV014
P932PMC publication ID4481666
P698PubMed publication ID25735597

P2093author name stringHua Lu
Xiang Zhou
Jun-Ming Liao
Peng Liao
Wen-Juan Liao
P2860cites workExpression of the ribosomal proteins Rplp0, Rplp1, and Rplp2 in gynecologic tumorsQ82261878
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB functionQ24293521
Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's diseaseQ24294458
IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7Q24297066
Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 functionQ24297664
Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational controlQ24298100
Diamond-Blackfan anemia with mandibulofacial dystostosis is heterogeneous, including the novel DBA genes TSR2 and RPS28Q24299499
The Shwachman-Diamond SBDS protein localizes to the nucleolusQ24300969
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulationQ24301668
Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actionsQ24301813
The human Shwachman-Diamond syndrome protein, SBDS, associates with ribosomal RNAQ24304508
Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translationQ24306776
Identification of RPS14 as a 5q- syndrome gene by RNA interference screenQ24306795
Altered cellular responses by varying expression of a ribosomal protein gene: sequential coordination of enhancement and suppression of ribosomal protein S3a gene expression induces apoptosisQ24311549
DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expressionQ24313051
Ribosomal protein S3 interacts with TRADD to induce apoptosis through caspase dependent JNK activationQ24314607
Inhibition of c-Myc activity by ribosomal protein L11Q24315370
Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulatorQ24318162
Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domainQ24321357
RPS19 mutations in patients with Diamond-Blackfan anemiaQ24321535
Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemiaQ24321881
Ribosomal protein S3, a new substrate of Akt, serves as a signal mediator between neuronal apoptosis and DNA repairQ24337831
Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemiaQ24337910
Repression of RNA polymerase I transcription by the tumor suppressor p53Q24552501
Inhibition of HDM2 and activation of p53 by ribosomal protein L23Q24562880
Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionQ24562892
The nucleolus under stressQ24597470
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availabilityQ24607244
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexesQ24608783
Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosisQ24609567
Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemiaQ24642192
Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patientsQ24643416
Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2Q24646511
Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint PathwayQ24648370
Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26Q24653892
Ribosomal protein S19 interacts with macrophage migration inhibitory factor and attenuates its pro-inflammatory functionQ24655352
Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradationQ24673794
A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleosteminQ24678915
Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypesQ27329518
Hepatitis C Virus 3'X Region Interacts with Human Ribosomal ProteinsQ27469767
RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESsQ27490486
Making ribosomesQ27930690
Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expressionQ27931583
TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.Q27933425
A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell sizeQ27936478
The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeastQ27936929
Ribosomal proteins and human diseases: pathogenesis, molecular mechanisms, and therapeutic implicationsQ34435519
Mycophenolic acid activation of p53 requires ribosomal proteins L5 and L11Q34588852
Ribosomal protein insufficiency and the minute syndrome in Drosophila: a dose-response relationship.Q34603415
5-fluorouracil activation of p53 involves an MDM2-ribosomal protein interactionQ34605000
Cisplatin inhibits synthesis of ribosomal RNA in vivoQ34669295
Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cellsQ34707415
Characterization of the Interaction between hantavirus nucleocapsid protein (N) and ribosomal protein S19 (RPS19).Q34719888
Low expression of the X-linked ribosomal protein S4 in human serous epithelial ovarian cancer is associated with a poor prognosisQ34783507
Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX networkQ34850281
The flavonoid apigenin downregulates CDK1 by directly targeting ribosomal protein S9.Q34979753
Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stressQ35067659
Ribosomal protein S6 interacts with the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirusQ35192690
Signaling to p53: ribosomal proteins find their way.Q35206381
Eukaryotic ribosomal protein RPS25 interacts with the conserved loop region in a dicistroviral intergenic internal ribosome entry siteQ35781839
Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteinsQ35830128
A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity.Q35914617
Ribosomal protein metallopanstimulin-1 impairs multiple myeloma CAG cells growth and inhibits fibroblast growth factor receptor 3.Q36062902
Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas developmentQ36144962
Large ribosomal protein 4 increases efficiency of viral recoding sequencesQ36154955
Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejectionQ36298271
Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B.Q36370851
Phosphorylation of ribosomal protein S3 and antiapoptotic TRAF2 protein mediates radioresistance in non-small cell lung cancer cellsQ36579445
Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerasesQ36623674
Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway.Q36736875
Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shuntingQ36757031
Splicing-factor oncoprotein SRSF1 stabilizes p53 via RPL5 and induces cellular senescenceQ36772205
Rig-I regulates NF-κB activity through binding to Nf-κb1 3'-UTR mRNAQ36782085
Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylationQ36792131
The GAIT system: a gatekeeper of inflammatory gene expression.Q36798907
Crosstalk between c-Myc and ribosome in ribosomal biogenesis and cancerQ36942685
Genome-wide polysome profiling reveals an inflammation-responsive posttranscriptional operon in gamma interferon-activated monocytesQ37033670
Ribosomal protein S14 negatively regulates c-Myc activityQ37048407
Coordinate transcriptional and translational repression of p53 by TGF-β1 impairs the stress responseQ37075390
Ribosomal and hematopoietic defects in induced pluripotent stem cells derived from Diamond Blackfan anemia patients.Q37083952
Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemiaQ33645930
Ribosomopathies: human disorders of ribosome dysfunctionQ33806050
The 5' untranslated region of the human T-cell lymphotropic virus type 1 mRNA enables cap-independent translation initiationQ33887817
Overlapping functions of the pRb family in the regulation of rRNA synthesisQ33969313
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.Q33973841
RPS3a over-expressed in HBV-associated hepatocellular carcinoma enhances the HBx-induced NF-κB signaling via its novel chaperoning functionQ33998857
Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia familiesQ34016409
Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activationQ34056010
Synthesis of the translational apparatus is regulated at the translational levelQ34058830
Mutation in ribosomal protein L21 underlies hereditary hypotrichosis simplexQ34171304
Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesisQ34178921
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemiaQ34223265
Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26.Q34246768
Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stressesQ34275810
Ribosomal protein SA haploinsufficiency in humans with isolated congenital aspleniaQ34338736
Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 inductionQ39595474
Chemotherapeutic drugs inhibit ribosome biogenesis at various levelsQ39738796
Identification of ribosomal protein L19 as a novel tumor antigen recognized by autologous cytotoxic T lymphocytes in lung adenocarcinomaQ39792348
Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesisQ39802021
Ribosomal protein S7 is both a regulator and a substrate of MDM2Q39812243
Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.Q39992844
A new database for ribosomal protein genes which are mutated in Diamond-Blackfan AnemiaQ40049095
Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiencyQ40890351
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemiaQ41296537
Activity of RNA polymerase I transcription factor UBF blocked by Rb gene productQ41361034
Alterations of tumor suppressor genes in bladder cancer.Q41495012
Multiple ribosomal proteins are expressed at high levels in developing zebrafish endoderm and are required for normal exocrine pancreas developmentQ41580681
Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond-Blackfan anemiaQ41983912
Interaction of Hantavirus Nucleocapsid Protein with Ribosomal Protein S19Q42227809
Enhanced expression of translation factor mRNAs in hepatocellular carcinoma.Q42492339
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activationQ42572950
p53 is a general repressor of RNA polymerase III transcriptionQ42645736
Ribosomal protein S19 is a novel therapeutic agent in inflammatory kidney disease.Q43744487
The ribosomal protein S26 regulates p53 activity in response to DNA damageQ45395590
Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.Q45995796
HIP/RPL29 down-regulation accompanies terminal chondrocyte differentiationQ47688675
The minute genes in Drosophila and their molecular functions.Q47791284
Mutations in the ribosomal protein gene RPL10 suggest a novel modulating disease mechanism for autismQ48434105
Downregulation of ribosomal protein S6 inhibits the growth of non-small cell lung cancer by inducing cell cycle arrest, rather than apoptosis.Q51698975
Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer.Q54273913
Repression of RNA polymerase III transcription by the retinoblastoma proteinQ58450660
Nucleolar exit of RNF8 and BRCA1 in response to DNA damageQ59123049
Effect of protein synthesis inhibitors and low concentrations of actinomycin D on ribosomal RNA synthesisQ66972415
Ultrastructural changes in nucleoli and fibrillar centers under the effect of local ultraviolet microbeam irradiation of interphase culture cellsQ69948317
Inhibition of RNA synthesis by actinomycin D: Characteristic dose-response of different RNA speciesQ71647340
Specific inhibition of pre-ribosomal RNA processing in extracts from the lymphosarcoma cells treated with 5-fluorouracilQ72769104
Enhanced expression of S8, L12, L23a, L27 and L30 ribosomal protein mRNAs in human hepatocellular carcinomaQ77295312
Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1.Q27938728
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin proteaseQ27938863
Systematic identification of pathways that couple cell growth and division in yeastQ27939933
Central role of Ifh1p-Fhl1p interaction in the synthesis of yeast ribosomal proteinsQ27940360
Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1Q28141914
Regulation of HDM2 activity by the ribosomal protein L11Q28184745
Ribosomal proteins S13 and L23 promote multidrug resistance in gastric cancer cells by suppressing drug-induced apoptosisQ28262344
KBF1 (p50 NF-kappa B homodimer) acts as a repressor of H-2Kb gene expression in metastatic tumor cellsQ28269339
Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5Q28276949
A ribosome-specialized translation initiation pathway is required for cap-dependent translation of vesicular stomatitis virus mRNAsQ28279614
The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemiaQ28297163
Mutational landscape and significance across 12 major cancer typesQ28300353
DNA binding of repressor nuclear factor-kappaB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunitQ28301936
Identification of mutations in the ribosomal protein L5 (RPL5) and ribosomal protein L11 (RPL11) genes in Czech patients with Diamond-Blackfan anemiaQ28308133
Ribosomal protein S7 regulates arsenite-induced GADD45α expression by attenuating MDM2-mediated GADD45α ubiquitination and degradationQ28383493
Attenuation of 40S ribosomal subunit abundance differentially affects host and HCV translation and suppresses HCV replicationQ28481243
Ablation of ribosomal protein L22 selectively impairs alphabeta T cell development by activation of a p53-dependent checkpointQ28504538
Ribosomal protein L17, RpL17, is an inhibitor of vascular smooth muscle growth and carotid intima formationQ28573822
Global growth deficiencies in mice lacking the ribosomal protein HIP/RPL29Q28586543
Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6Q28588241
RPLP1, a crucial ribosomal protein for embryonic development of the nervous systemQ28589114
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53Q28589774
Loss of the mouse ortholog of the shwachman-diamond syndrome gene (Sbds) results in early embryonic lethalityQ28590641
An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 InteractionQ28590794
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterningQ28591034
Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cellsQ28910201
A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growthQ28910214
Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolinQ28910229
Cooperation between the ribosomal proteins L5 and L11 in the p53 pathwayQ28910446
Missing pieces in the NF-kappaB puzzleQ29547864
Pre-ribosomes on the road from the nucleolus to the cytoplasmQ29616319
Does the ribosome translate cancer?Q29618775
The TOR signaling cascade regulates gene expression in response to nutrientsQ29620801
Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.Q29976922
Tor Pathway Regulates Rrn3p-dependent Recruitment of Yeast RNA Polymerase I to the Promoter but Does Not Participate in Alteration of the Number of Active GenesQ30449935
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaksQ33286997
A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndromeQ33579912
Critical role of nucleostemin in pre-rRNA processingQ37099197
Ribosomal protein L29/HIP deficiency delays osteogenesis and increases fragility of adult bone in miceQ37101839
The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.Q37192095
Human ribosomal protein S13 promotes gastric cancer growth through down-regulating p27(Kip1).Q37294503
Small ribosomal protein subunit S7 suppresses ovarian tumorigenesis through regulation of the PI3K/AKT and MAPK pathwaysQ37297766
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supplyQ37394486
Targeted disruption of the ribosomal protein S19 gene is lethal prior to implantationQ37424374
How common are extraribosomal functions of ribosomal proteins?Q37442012
The selective estrogen receptor-alpha coactivator, RPL7, and sexual differentiation of the songbird brainQ37518483
Regulation of the HDM2-p53 pathway by ribosomal protein L6 in response to ribosomal stressQ37574238
5S ribosomal RNA is an essential component of a nascent ribosomal precursor complex that regulates the Hdm2-p53 checkpointQ37592131
Ribosomal mutations cause p53-mediated dark skin and pleiotropic effectsQ37691461
Translational control in cancer.Q37717999
MYC as a regulator of ribosome biogenesis and protein synthesisQ37718002
Ribosomal protein s3: a multifunctional target of attaching/effacing bacterial pathogensQ37899039
Scission of the p53-MDM2 Loop by Ribosomal ProteinsQ38059701
Ribosomal proteins as novel players in tumorigenesisQ38174514
Nucleolar stress in Diamond Blackfan anemia pathophysiologyQ38177600
Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblastsQ38330517
Knockdown of ribosomal protein S7 causes developmental abnormalities via p53 dependent and independent pathways in zebrafishQ38335349
Extraribosomal function of metallopanstimulin-1: reducing paxillin in head and neck squamous cell carcinoma and inhibiting tumor growthQ38351861
Ribosomal protein L11 recruits miR-24/miRISC to repress c-Myc expression in response to ribosomal stressQ38630478
Ribosomal proteins L11 and L5 activate TAp73 by overcoming MDM2 inhibitionQ38949296
Ribosomal proteins L5 and L11 co-operatively inactivate c-Myc via RNA-induced silencing complexQ39076270
Ribosomal protein S14 silencing inhibits growth of acute myeloid leukemia transformed from myelodysplastic syndromes via activating p53.Q39090567
Metallopanstimulin-1 regulates invasion and migration of gastric cancer cells partially through integrin β4.Q39134564
Nucleolar trafficking of the mouse mammary tumor virus gag protein induced by interaction with ribosomal protein L9.Q39248067
Identification of ribosomal protein S25 (RPS25)-MDM2-p53 regulatory feedback loop.Q39317432
Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint.Q39347844
Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stressQ39385222
Knockdown of metallopanstimulin-1 inhibits NF-κB signaling at different levels: the role of apoptosis induction of gastric cancer cellsQ39499352
Ribosomal protein RPL41 induces rapid degradation of ATF4, a transcription factor critical for tumour cell survival in stressQ39517528
Retinoblastoma protein disrupts interactions required for RNA polymerase III transcriptionQ39540188
Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathwayQ39575463
P433issue2
P304page(s)92-104
P577publication date2015-03-03
P1433published inJournal of Molecular Cell BiologyQ2456339
P1476titleRibosomal proteins: functions beyond the ribosome
P478volume7