The Hippo pathway controls border cell migration through distinct mechanisms in outer border cells and polar cells of the Drosophila ovary

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The Hippo pathway controls border cell migration through distinct mechanisms in outer border cells and polar cells of the Drosophila ovary is …
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scholarly articleQ13442814

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P356DOI10.1534/GENETICS.114.167346
P932PMC publication ID4224154
P698PubMed publication ID25161211

P2093author name stringTsu-Wei Wang
Jenn-Yah Yu
Tzu-Huai Lin
Tsung-Han Yeh
P2860cites workAjuba LIM proteins are negative regulators of the Hippo signaling pathwayQ24304074
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathwaysQ24317164
TEAD mediates YAP-dependent gene induction and growth controlQ24336045
The Hippo Signaling Pathway in Development and CancerQ24603986
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in DrosophilaQ24670738
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 ampliconQ24682018
Microtubules and Lis-1/NudE/Dynein Regulate Invasive Cell-on-Cell Migration in DrosophilaQ27334393
Epithelial-mesenchymal transitions in development and diseaseQ27860630
Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in DrosophilaQ28236392
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAPQ28266862
SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in DrosophilaQ28271058
Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signalingQ28507203
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiationQ28507317
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liverQ28587974
Analysis of genetic mosaics in developing and adult Drosophila tissuesQ29617838
Elucidation of a universal size-control mechanism in Drosophila and mammalsQ29618935
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosisQ29619851
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and wartsQ29620457
Effective guidance of collective migration based on differences in cell statesQ30505173
The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cellsQ30540532
The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarityQ33323368
Coupling of Hedgehog and Hippo pathways promotes stem cell maintenance by stimulating proliferationQ33601460
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathwayQ33644875
dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cellsQ33707393
Kibra is a regulator of the Salvador/Warts/Hippo signaling networkQ33754234
Transmission of mitochondrial mutations and action of purifying selection in Drosophila melanogasterQ33880929
Yki/YAP, Sd/TEAD and Hth/MEIS Control Tissue Specification in the Drosophila Eye Disc EpitheliumQ33979785
Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivoQ34090534
Paracrine Signaling through the JAK/STAT Pathway Activates Invasive Behavior of Ovarian Epithelial Cells in DrosophilaQ34108115
Systematic analysis of the transcriptional switch inducing migration of border cellsQ34201860
Hippo Pathway Effector Yap Is an Ovarian Cancer OncogeneQ34267908
Organogenesis and tumorigenesis: Insight from the JAK/STAT pathway in the Drosophila eyeQ34275385
The Hippo tumor suppressor pathway regulates intestinal stem cell regenerationQ34342510
The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regenerationQ34342516
Opposite feedbacks in the Hippo pathway for growth control and neural fate.Q34367472
The level of C/EBP protein is critical for cell migration during Drosophila oogenesis and is tightly controlled by regulated degradationQ47071320
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathwayQ47071830
Multiple EGFR ligands participate in guiding migrating border cells.Q47072013
Eyes absent, a key repressor of polar cell fate during Drosophila oogenesisQ47072399
Spatially localized Kuzbanian required for specific activation of Notch during border cell migrationQ47072427
Guidance of cell migration by EGF receptor signaling during Drosophila oogenesisQ47072682
Homeodomain-interacting protein kinase regulates Yorkie activity to promote tissue growthQ47072805
slow border cells, a locus required for a developmentally regulated cell migration during oogenesis, encodes Drosophila C/EBPQ48153939
Requirement for JAK/STAT signaling throughout border cell migration in DrosophilaQ52045195
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in DrosophilaQ52100108
The JAK/STAT pathway is required for border cell migration during Drosophila oogenesisQ52124884
Systematic gain-of-function genetics in Drosophila.Q52188274
A role for the Drosophila segment polarity gene armadillo in cell adhesion and cytoskeletal integrity during oogenesis.Q52544417
The Hippo pathway controls polar cell fate through Notch signaling during Drosophila oogenesisQ52724890
Hippo signaling regulatesDrosophilaintestine stem cell proliferation through multiple pathwaysQ34396983
Control of cell proliferation and apoptosis by mob as tumor suppressor, matsQ34402685
Hippo signaling: growth control and beyondQ34625638
Herding Hippos: regulating growth in flies and man.Q35008892
The Jak/STAT pathway in model organisms: emerging roles in cell movementQ35024636
Border-cell migration: the race is on.Q35038279
Tao-1 Phosphorylates Hippo/MST Kinases to Regulate the Hippo-Salvador-Warts Tumor Suppressor PathwayQ35552770
AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma.Q35899490
Mass transit: epithelial morphogenesis in the Drosophila egg chamberQ36036932
Ovarian cancer metastasis: integrating insights from disparate model organismsQ36111930
The salvador-warts-hippo pathway is required for epithelial proliferation and axis specification in DrosophilaQ36204208
Control of mitochondrial structure and function by the Yorkie/YAP oncogenic pathwayQ36240904
Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cellsQ36571746
In vivo regulation of Yorkie phosphorylation and localization.Q36663448
The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor networkQ36743530
Modeling migration and metastasis in DrosophilaQ36840769
Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notchQ36982935
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammalsQ37105079
Border-cell migration requires integration of spatial and temporal signals by the BTB protein AbruptQ37175539
In vivo analysis of Yorkie phosphorylation sites.Q37239572
Yorkie: the final destination of Hippo signaling.Q37746333
The Hippo pathway and human cancer.Q38087215
Analysis of cell migration using whole-genome expression profiling of migratory cells in the Drosophila ovaryQ38314569
Regulation ofDrosophilaglial cell proliferation by Merlin-Hippo signalingQ38979328
The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene.Q39592989
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size controlQ40015415
Drosophila warts--tumor suppressor and member of the myotonic dystrophy protein kinase family.Q40475118
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanismsQ41980171
Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell ProliferationQ42109247
Requirement for Par-6 and Bazooka in Drosophila border cell migrationQ42468506
Modulating F-actin organization induces organ growth by affecting the Hippo pathwayQ42760112
Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in DrosophilaQ43550384
Guidance of cell migration by the Drosophila PDGF/VEGF receptorQ43762442
PVF1, a PDGF/VEGF homolog, is sufficient to guide border cells and interacts genetically with Taiman.Q44480680
Spatiotemporal rescue of memory dysfunction in DrosophilaQ44681267
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferationQ46192247
Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancerQ47070112
Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferationQ47070580
The Drosophila cytokine receptor Domeless controls border cell migration and epithelial polarization during oogenesis.Q47070625
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcell migrationQ189092
DrosophilaQ312154
P304page(s)1087-1099
P577publication date2014-08-26
P1433published inGeneticsQ3100575
P1476titleThe Hippo pathway controls border cell migration through distinct mechanisms in outer border cells and polar cells of the Drosophila ovary
P478volume198

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cites work (P2860)
Q53723856A hormonal cue promotes timely follicle cell migration by modulating transcription profiles
Q90193380Characteristics of in Vivo Model Systems for Ovarian Cancer Studies
Q27318196Dchs1-Fat4 regulation of polarized cell behaviours during skeletal morphogenesis.
Q42318129Hippo signaling promotes JNK-dependent cell migration
Q37079565Identification of Novel Regulators of the JAK/STAT Signaling Pathway that Control Border Cell Migration in the Drosophila Ovary.
Q93064054Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
Q90377005New slbo-Gal4 driver lines for the analysis of border cell migration during Drosophila oogenesis
Q50422446Rap1 Negatively Regulates the Hippo Pathway to Polarize Directional Protrusions in Collective Cell Migration.
Q33861208The Hippo pathway acts downstream of the Hedgehog signaling to regulate follicle stem cell maintenance in the Drosophila ovary
Q35099085The Hippo pathway regulates homeostatic growth of stem cell niche precursors in the Drosophila ovary
Q36412946Tousled-like kinase regulates cytokine-mediated communication between cooperating cell types during collective border cell migration
Q47149836Yorkie regulates epidermal wound healing in Drosophila larvae independently of cell proliferation and apoptosis.

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