scholarly article | Q13442814 |
P50 | author | Wolf-Dietrich Heyer | Q63309380 |
P2093 | author name string | Vladimir I Bashkirov | |
Edwin Haghnazari | |||
Elena V Bashkirova | |||
P2860 | cites work | Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome | Q22011001 |
Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2 | Q24319816 | ||
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1 | Q24551095 | ||
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro | Q24656275 | ||
II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides | Q27627122 | ||
The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms | Q27628846 | ||
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway | Q39459511 | ||
Threonine-11, phosphorylated by Rad3 and atm in vitro, is required for activation of fission yeast checkpoint kinase Cds1 | Q39530422 | ||
Chk2 activation and phosphorylation-dependent oligomerization | Q39674829 | ||
Mitotic DNA damage and replication checkpoints in yeast | Q40352474 | ||
Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs | Q41331128 | ||
The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage | Q41854894 | ||
The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors | Q42672394 | ||
Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. | Q42687620 | ||
Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. | Q43711748 | ||
Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae | Q46200700 | ||
DUN1 encodes a protein kinase that controls the DNA damage response in yeast | Q48087375 | ||
The riddle of MAP kinase signaling specificity | Q58212672 | ||
Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways | Q58883742 | ||
DNA damage checkpoints update: getting molecular | Q62657002 | ||
A DNA damage response pathway controlled by Tel1 and the Mre11 complex | Q64388109 | ||
Regulation of SNM1, an inducible Saccharomyces cerevisiae gene required for repair of DNA cross-links | Q71073759 | ||
Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms | Q73153090 | ||
Analysis of budding yeast kinases controlled by DNA damage | Q73572483 | ||
Role of the N-terminal forkhead-associated domain in the cell cycle checkpoint function of the Rad53 kinase | Q73693369 | ||
FHA: a signal transduction domain with diverse specificity and function | Q74471745 | ||
MEC1-dependent phosphorylation of Rad9p in response to DNA damage | Q77231583 | ||
Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2 | Q27639080 | ||
Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate | Q27639362 | ||
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains | Q27860528 | ||
The conformational plasticity of protein kinases | Q27860946 | ||
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry | Q27861116 | ||
Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase | Q27930725 | ||
Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae | Q27933444 | ||
Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae | Q27933460 | ||
The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria | Q27933751 | ||
SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase. | Q27935086 | ||
Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks | Q27935124 | ||
The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor | Q27935222 | ||
Mrc1 transduces signals of DNA replication stress to activate Rad53. | Q27935521 | ||
The FHA domain, a phosphoamino acid binding domain involved in the DNA damage response pathway | Q27935644 | ||
Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint | Q27937738 | ||
A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools | Q27938474 | ||
A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription. | Q27938547 | ||
Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway | Q27938580 | ||
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint | Q27939822 | ||
The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain | Q28207961 | ||
Replacement of chromosome segments with altered DNA sequences constructed in vitro | Q29614231 | ||
Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways | Q29615271 | ||
The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast | Q29620732 | ||
RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast | Q30448350 | ||
Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. | Q30657462 | ||
Rad54 protein stimulates heteroduplex DNA formation in the synaptic phase of DNA strand exchange via specific interactions with the presynaptic Rad51 nucleoprotein filament | Q30663367 | ||
The FHA domain is a modular phosphopeptide recognition motif. | Q33285631 | ||
Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint | Q33285672 | ||
Sir-Ku-itous routes to make ends meet | Q33684024 | ||
Sensing and responding to DNA damage. | Q33840475 | ||
DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpoints | Q33963987 | ||
The FHA domain mediates phosphoprotein interactions. | Q34078695 | ||
Regulation of G protein-initiated signal transduction in yeast: paradigms and principles | Q34275492 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA damage | Q5205747 |
P304 | page(s) | 1441-1452 | |
P577 | publication date | 2003-02-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase | |
P478 | volume | 23 |
Q40522020 | A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation |
Q33535179 | A proteome-wide analysis of kinase-substrate network in the DNA damage response |
Q33522877 | A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae |
Q31156501 | Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae |
Q36119385 | An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth |
Q44918067 | Cds1 phosphorylation by Rad3-Rad26 kinase is mediated by forkhead-associated domain interaction with Mrc1. |
Q42837739 | Checkpoint kinases regulate a global network of transcription factors in response to DNA damage |
Q37357566 | Checkpoint regulation of replication forks: global or local? |
Q35616094 | Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity |
Q42060947 | DNA damage checkpoints inhibit mitotic exit by two different mechanisms |
Q46548059 | DNA damage-induced phosphorylation of Rad55 protein as a sentinel for DNA damage checkpoint activation in S. cerevisiae |
Q47834669 | Diverse but overlapping functions of the two forkhead-associated (FHA) domains in Rad53 checkpoint kinase activation |
Q33619823 | Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag. |
Q36297194 | Functional analysis with a barcoder yeast gene overexpression system |
Q42648375 | Genetic interaction of RAD53 protein kinase with histones is important for DNA replication |
Q31033545 | Identification of phosphorylation sites on the yeast ribonucleotide reductase inhibitor Sml1. |
Q34573274 | Isolation and characterization of novel xrs2 mutations in Saccharomyces cerevisiae |
Q92416794 | Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats |
Q33611684 | Mechanism of Dun1 activation by Rad53 phosphorylation in Saccharomyces cerevisiae. |
Q35783683 | Mechanisms regulating the protein kinases of Saccharomyces cerevisiae |
Q36478038 | Mek1 stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during yeast meiosis |
Q37122913 | Molecular basis of the essential s phase function of the rad53 checkpoint kinase |
Q41122695 | PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response |
Q37499545 | Perspectives on the DNA damage and replication checkpoint responses in Saccharomyces cerevisiae. |
Q39126666 | Phosphorylation of Rad55 on serines 2, 8, and 14 is required for efficient homologous recombination in the recovery of stalled replication forks |
Q35536247 | Phosphorylation of Sae2 Mediates Forkhead-associated (FHA) Domain-specific Interaction and Regulates Its DNA Repair Function. |
Q27933709 | Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage. |
Q33649550 | Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance. |
Q35973264 | Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases |
Q39852750 | Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling |
Q61948488 | Rad9a is involved in chromatin decondensation and post-zygotic embryo development in mice |
Q35786136 | Regulation of NEIL1 protein abundance by RAD9 is important for efficient base excision repair |
Q35619367 | Regulation of ribonucleotide reductase in response to iron deficiency |
Q59066655 | Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations |
Q38293464 | Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease |
Q35143822 | Saccharomyces cerevisiae chromatin-assembly factors that act during DNA replication function in the maintenance of genome stability. |
Q27937332 | Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways |
Q39769852 | The DNA damage checkpoint pathway promotes extensive resection and nucleotide synthesis to facilitate homologous recombination repair and genome stability in fission yeast. |
Q39945725 | The DNA damage checkpoint pathways exert multiple controls on the efficiency and outcome of the repair of a double-stranded DNA gap. |
Q38089570 | The DNA damage checkpoint response to replication stress: A Game of Forks |
Q35634055 | The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53. |
Q27931948 | Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Small Subunit Localization in Response to Iron Deficiency. |
Q34056390 | Yeast Dun1 kinase regulates ribonucleotide reductase inhibitor Sml1 in response to iron deficiency |