| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2003PNAS..100.6628Y |
| P356 | DOI | 10.1073/PNAS.1131932100 |
| P932 | PMC publication ID | 164498 |
| P698 | PubMed publication ID | 12732713 |
| P5875 | ResearchGate publication ID | 10772217 |
| P50 | author | JoAnne Stubbe | Q55280 |
| Deborah L. Perlstein | Q42123283 | ||
| P2093 | author name string | Zhen Zhang | |
| Mingxia Huang | |||
| Xiuxiang An | |||
| Brigid Bucci | |||
| Ruojin Yao | |||
| P2860 | cites work | Linkage of ATM to cell cycle regulation by the Chk2 protein kinase | Q22008502 |
| Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization | Q24533531 | ||
| The mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae | Q27930386 | ||
| Rnr4p, a novel ribonucleotide reductase small-subunit protein | Q27930465 | ||
| NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae | Q27930735 | ||
| Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly | Q27931632 | ||
| New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. | Q27932226 | ||
| Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex | Q27932298 | ||
| Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae | Q27933444 | ||
| The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. | Q27934363 | ||
| Yeast Sml1, a protein inhibitor of ribonucleotide reductase. | Q27934371 | ||
| The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor | Q27935222 | ||
| A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools | Q27938474 | ||
| Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7. | Q27939332 | ||
| Yeast ribonucleotide reductase has a heterodimeric iron-radical-containing subunit | Q27939596 | ||
| Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint | Q27939822 | ||
| The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
| Genetic instabilities in human cancers | Q28131826 | ||
| A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage | Q28138556 | ||
| Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits | Q28180311 | ||
| DNA double-strand breaks: signaling, repair and the cancer connection | Q28204231 | ||
| p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint | Q28207139 | ||
| The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage | Q28343318 | ||
| Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C | Q28611955 | ||
| ATM and related protein kinases: safeguarding genome integrity | Q29547735 | ||
| The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation | Q29615268 | ||
| Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways | Q29615271 | ||
| Cell cycle checkpoint signaling through the ATM and ATR kinases | Q29617837 | ||
| Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle | Q29619289 | ||
| The evolution of ribonucleotide reduction revisited | Q31884365 | ||
| Why multiple small subunits (Y2 and Y4) for yeast ribonucleotide reductase? Toward understanding the role of Y4. | Q33942942 | ||
| Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p | Q33948213 | ||
| Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae | Q33959719 | ||
| Mutational and structural analyses of the ribonucleotide reductase inhibitor Sml1 define its Rnr1 interaction domain whose inactivation allows suppression of mec1 and rad53 lethality | Q33966744 | ||
| Ribonucleotide reductases | Q34067559 | ||
| A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit | Q34108358 | ||
| Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase | Q34473101 | ||
| Maintenance of genome stability in Saccharomyces cerevisiae | Q34762852 | ||
| The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae | Q36222251 | ||
| Identification and isolation of the gene encoding the small subunit of ribonucleotide reductase from Saccharomyces cerevisiae: DNA damage-inducible gene required for mitotic viability | Q36447249 | ||
| MCM2-7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not maintain, the S-phase checkpoint | Q39231854 | ||
| Reduction of Ribonucleotides | Q39805408 | ||
| DNA damage and cell cycle regulation of ribonucleotide reductase | Q40830894 | ||
| Mammalian S-phase checkpoint integrity is dependent on transformation status and purine deoxyribonucleosides | Q40899186 | ||
| DNA damage checkpoint in budding yeast. | Q42655040 | ||
| Controlled protein degradation regulates ribonucleotide reductase activity in proliferating mammalian cells during the normal cell cycle and in response to DNA damage and replication blocks | Q42803744 | ||
| Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase | Q44311904 | ||
| Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase | Q45078328 | ||
| DUN1 encodes a protein kinase that controls the DNA damage response in yeast | Q48087375 | ||
| Cross-talk between the allosteric effector-binding sites in mouse ribonucleotide reductase | Q50336025 | ||
| A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage | Q54162557 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Ribonucleotide-diphosphate reductase subunit RNR2 YJL026W | Q27550041 |
| Ribonucleotide-diphosphate reductase subunit RNR4 YGR180C | Q27550527 | ||
| Ribonucleotide-diphosphate reductase subunit RNR3 YIL066C | Q27551690 | ||
| Ribonucleotide-diphosphate reductase subunit RNR1 YER070W | Q27552791 | ||
| P304 | page(s) | 6628-33 | |
| P577 | publication date | 2003-05-27 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways | |
| P478 | volume | 100 |
| Q30547352 | A chemostat array enables the spatio-temporal analysis of the yeast proteome |
| Q28473344 | A dynamic stochastic model for DNA replication initiation in early embryos |
| Q44838357 | ATR regulates a G2-phase cell-cycle checkpoint in Arabidopsis thaliana |
| Q43144012 | Analysis of changes in protein level and subcellular localization during cell cycle progression using the budding yeast Saccharomyces cerevisiae |
| Q48105213 | Arabidopsis ribonucleotide reductases are critical for cell cycle progression, DNA damage repair, and plant development |
| Q41429472 | Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast |
| Q34570125 | Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiae |
| Q37021683 | Cell cycle- and ribonucleotide reductase-driven changes in mtDNA copy number influence mtDNA Inheritance without compromising mitochondrial gene expression |
| Q94561403 | Cellular Analysis and Comparative Transcriptomics Reveal the Tolerance Mechanisms of Candida tropicalis Toward Phenol |
| Q43110805 | Checkpoint-dependent RNR induction promotes fork restart after replicative stress |
| Q40882892 | Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1 |
| Q52407307 | Clb6-Cdc28 Promotes Ribonucleotide Reductase Subcellular Redistribution during S Phase. |
| Q26829008 | Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses |
| Q33674147 | Conserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesis |
| Q35611548 | Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae. |
| Q27932089 | Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1. |
| Q34611390 | Cotransport of the heterodimeric small subunit of the Saccharomyces cerevisiae ribonucleotide reductase between the nucleus and the cytoplasm |
| Q37417534 | Cytoplasmic localization of Hug1p, a negative regulator of the MEC1 pathway, coincides with the compartmentalization of Rnr2p-Rnr4p |
| Q41510400 | DNA damage induced by the anticodon nuclease from a Pichia acaciae killer strain is linked to ribonucleotide reductase depletion |
| Q38118223 | DNA damage response: three levels of DNA repair regulation |
| Q43137350 | Determination of the in vivo stoichiometry of tyrosyl radical per betabeta' in Saccharomyces cerevisiae ribonucleotide reductase |
| Q33374228 | Dif1 controls subcellular localization of ribonucleotide reductase by mediating nuclear import of the R2 subunit |
| Q35633411 | Dif1 is a DNA-damage-regulated facilitator of nuclear import for ribonucleotide reductase |
| Q39019272 | Differential chromatin proteomics of the MMS-induced DNA damage response in yeast |
| Q36209899 | Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress |
| Q37236549 | Dynamic SPR monitoring of yeast nuclear protein binding to a cis-regulatory element |
| Q35760007 | Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype |
| Q33819631 | Functional dissection of a HECT ubiquitin E3 ligase |
| Q28264035 | Genetic instability in budding and fission yeast-sources and mechanisms |
| Q47696706 | Genome reprogramming in Saccharomyces cerevisiae upon nonylphenol exposure. |
| Q50439280 | Genotoxicity of chemical compounds identification and assessment by yeast cells transformed with GFP reporter constructs regulated by the PLM2 or DIN7 promoter |
| Q33758570 | HIV-1 Transmission, Replication Fitness and Disease Progression |
| Q34271790 | Hydroxyurea Arrests DNA Replication by a Mechanism That Preserves Basal dNTP Pools |
| Q27939432 | Identification and characterization of CRT10 as a novel regulator of Saccharomyces cerevisiae ribonucleotide reductase genes. |
| Q27932549 | Identification of a mitochondrial transporter for pyrimidine nucleotides in Saccharomyces cerevisiae: bacterial expression, reconstitution and functional characterization |
| Q36338771 | Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response |
| Q91900468 | Inhibition of white spot syndrome virus in Litopenaeus vannamei shrimp by sequence-specific siRNA |
| Q27936372 | Local statistics allow quantification of cell-to-cell variability from high-throughput microscope images |
| Q34313399 | Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase |
| Q30845065 | Mechanisms of cell cycle control revealed by a systematic and quantitative overexpression screen in S. cerevisiae |
| Q37793347 | Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells |
| Q34609166 | Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools |
| Q26858881 | Metabolic remodeling in iron-deficient fungi |
| Q37878159 | Mind the gap: keeping UV lesions in check. |
| Q34013667 | Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast. |
| Q37748663 | Navigating the nucleotide excision repair threshold |
| Q27933989 | Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein |
| Q83520155 | Phenotypes associated with Saccharomyces cerevisiae Hug1 protein, a putative negative regulator of dNTP Levels, reveal similarities and differences with sequence-related Dif1 |
| Q47952981 | Phylogenetic sequence analysis and functional studies reveal compensatory amino acid substitutions in loop 2 of human ribonucleotide reductase |
| Q48112706 | Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. |
| Q35973264 | Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases |
| Q79745517 | RNR4 mutant alleles pso3-1 and rnr4Delta block induced mutation in Saccharomyces cerevisiae |
| Q35619367 | Regulation of ribonucleotide reductase in response to iron deficiency |
| Q40816185 | Replication in hydroxyurea: it's a matter of time |
| Q33699869 | Ribonucleotide reductase metallocofactor: assembly, maintenance and inhibition |
| Q36581114 | Ribonucleotide reductase small subunit M2 serves as a prognostic biomarker and predicts poor survival of colorectal cancers. |
| Q36976768 | Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage |
| Q35096702 | Ribosome synthesis-unrelated functions of the preribosomal factor Rrp12 in cell cycle progression and the DNA damage response. |
| Q35671871 | Rice stripe1-2 and stripe1-3 Mutants Encoding the Small Subunit of Ribonucleotide Reductase Are Temperature Sensitive and Are Required for Chlorophyll Biosynthesis |
| Q47628340 | Rnr1's role in telomere elongation cannot be replaced by Rnr3: a role beyond dNTPs? |
| Q42517422 | Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres. |
| Q27678275 | Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase |
| Q35844439 | Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1 |
| Q36529251 | S phase block following MEC1ATR inactivation occurs without severe dNTP depletion. |
| Q36316468 | S-phase checkpoint pathways stimulate the mobility of the retrovirus-like transposon Ty1. |
| Q42962767 | Single-cell analysis of ribonucleotide reductase transcriptional and translational response to DNA damage |
| Q36225123 | Structure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocket |
| Q60919740 | Structure-guided design of anti-cancer ribonucleotide reductase inhibitors |
| Q27932514 | Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation |
| Q27938358 | TOR signaling is a determinant of cell survival in response to DNA damage. |
| Q36353167 | Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy. |
| Q28080250 | The Cell Killing Mechanisms of Hydroxyurea |
| Q38089570 | The DNA damage checkpoint response to replication stress: A Game of Forks |
| Q28771296 | The Schizosaccharomyces pombe replication inhibitor Spd1 regulates ribonucleotide reductase activity and dNTPs by binding to the large Cdc22 subunit |
| Q27932048 | The WTM genes in budding yeast amplify expression of the stress-inducible gene RNR3. |
| Q27937686 | The active form of the Saccharomyces cerevisiae ribonucleotide reductase small subunit is a heterodimer in vitro and in vivo |
| Q39170062 | The available SRL3 deletion strain of Saccharomyces cerevisiae contains a truncation of DNA damage tolerance protein Mms2: Implications for Srl3 and Mms2 functions |
| Q28109405 | The iron metallome in eukaryotic organisms |
| Q34246788 | The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage |
| Q53629818 | Thioredoxin is required for deoxyribonucleotide pool maintenance during S phase. |
| Q34133608 | Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase |
| Q42134963 | Trm9-catalyzed tRNA modifications link translation to the DNA damage response |
| Q37518741 | UV-C response of the ribonucleotide reductase large subunit involves both E2F-mediated gene transcriptional regulation and protein subcellular relocalization in tobacco cells. |
| Q46246407 | Unique molecular mechanisms for maintenance and alteration of genetic information in the budding yeast Saccharomyces cerevisiae |
| Q27931948 | Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Small Subunit Localization in Response to Iron Deficiency. |
| Q34056390 | Yeast Dun1 kinase regulates ribonucleotide reductase inhibitor Sml1 in response to iron deficiency |
| Q38874192 | tRNA wobble modifications and protein homeostasis |
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