scholarly article | Q13442814 |
P2093 | author name string | Derek S Tan | |
Renato A Bauer | |||
Todd A Wenderski | |||
P2860 | cites work | Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes | Q27766090 |
Characteristics in the reactions of allylsilanes and their applications to versatile synthetic equivalents | Q30054146 | ||
Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform | Q31038453 | ||
A solution- and solid-phase approach to tetrahydroquinoline-derived polycyclics having a 10-membered ring | Q33206660 | ||
Design and synthesis of medium-ring lactam libraries inspired by octalactin a. A convergent-divergent approach | Q33359155 | ||
Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective | Q33536938 | ||
An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors | Q33743418 | ||
Solid-phase synthesis and chemical space analysis of a 190-membered alkaloid/terpenoid-like library | Q33857987 | ||
Molecular properties that influence the oral bioavailability of drug candidates | Q34130727 | ||
A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion | Q34190644 | ||
Fundamental relationships between structure, reactivity, and biological activity for the duocarmycins and CC-1065. | Q37371583 | ||
Testing the conformational hypothesis of passive membrane permeability using synthetic cyclic peptide diastereomers. | Q46001611 | ||
Total synthesis of the aspercyclides. | Q46024123 | ||
Quantitative comparison of the relative cell permeability of cyclic and linear peptides. | Q53545017 | ||
Steganacin and steganangin, novel antileukemic lignan lactones from Steganotaenia araliacea. | Q55061546 | ||
Hydrofluoric acid catalyzed intramolecular Diels-Alder reactions | Q56698958 | ||
Flavonone and chalcone derivatives from Cryptocarya kurzii | Q72933416 | ||
Enantioselective total synthesis of (-)-heliannuol A | Q73071107 | ||
Ellagitannin Chemistry | Q77646202 | ||
Aspercyclide A–C, three novel fungal metabolites from Aspergillus sp. as inhibitors of high-affinity IgE receptor | Q78297209 | ||
Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions | Q79139293 | ||
Conformational constraint in protein ligand design and the inconsistency of binding entropy | Q80856569 | ||
Total synthesis of aspercyclide C | Q81633084 | ||
Neodihydrothebaine and bractazonine, two dibenz[d,f]azonine alkaloids of Papaver bracteatum | Q104388371 | ||
The structure elucidation of Rhazinilam, a new class of Alkaloids from the apocynaceae, by X-ray analysis | Q104395707 | ||
Sophoraside A, a new aromatic glycoside from the roots of Sophora japonica. | Q104921514 | ||
Two novel aromatic compounds from Caesalpinia sappan. | Q104996037 | ||
Novel sesquiterpene from bioactive fractions of cultivar sunflowers | Q105003593 | ||
P433 | issue | 1 | |
P921 | main subject | biomimetics | Q1145644 |
P304 | page(s) | 21-29 | |
P577 | publication date | 2012-11-18 | |
P1433 | published in | Nature Chemical Biology | Q904026 |
P1476 | title | Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion | |
P478 | volume | 9 |
Q58580325 | A Brief Overview of Two Major Strategies in Diversity-Oriented Synthesis: Build/Couple/Pair and Ring-Distortion |
Q36093023 | A Multidimensional Diversity-Oriented Synthesis Strategy for Structurally Diverse and Complex Macrocycles |
Q38798602 | A Palladium-Catalyzed Carbonylation Approach to Eight-Membered Lactam Derivatives with Antitumor Activity |
Q90093163 | A Scaffold-Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides |
Q36207545 | A Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine |
Q64992798 | A divergent synthetic pathway for pyrimidine-embedded medium-sized azacycles through an N-quaternizing strategy. |
Q55334009 | A diversity-oriented synthesis of bioactive benzanilides via a regioselective C(sp2)-H hydroxylation strategy. |
Q93133678 | A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings |
Q34993742 | A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling |
Q41898587 | A tandem isomerization/prins strategy: iridium(III)/Brønsted acid cooperative catalysis |
Q51766245 | Biogenetically inspired synthesis and skeletal diversification of indole alkaloids. |
Q41107892 | Capture-Collapse Heterocyclization: 1,3-Diazepanes by C-N Reductive Elimination from Rhodacyclopentanones |
Q52590901 | Chemical probes and drug leads from advances in synthetic planning and methodology. |
Q36167128 | Cheminformatic comparison of approved drugs from natural product versus synthetic origins |
Q48273532 | Construction of Nine-Membered Heterocycles through Palladium-Catalyzed Formal [5+4] Cycloaddition. |
Q35166727 | Direct comparison of linear and macrocyclic compound libraries as a source of protein ligands |
Q28817632 | Diversity-Oriented Synthesis of Natural-Product-like Libraries Containing a 3-Methylbenzofuran Moiety for the Discovery of New Chemical Elicitors |
Q35278303 | Diversity-oriented synthesis of drug-like macrocyclic scaffolds using an orthogonal organo- and metal catalysis strategy |
Q28821081 | Diversity-oriented synthetic strategy for developing a chemical modulator of protein-protein interaction |
Q47106457 | Impact of the structures of macrocyclic Michael acceptors on covalent proteasome inhibition. |
Q61881614 | Iterative Assembly of Macrocyclic Lactones using Successive Ring Expansion Reactions |
Q48149873 | Medium-Ring Nitrogen Heterocycles through Migratory Ring Expansion of Metalated Ureas |
Q51660636 | Metal-free tandem oxidative C(sp(3))-H bond functionalization of alkanes and dearomatization of N-phenyl-cinnamamides: access to alkylated 1-azaspiro[4.5]decanes. |
Q37091004 | Modular, One-Pot, Sequential Aziridine Ring Opening-S(N)Ar Strategy to 7-, 10-, and 11-Membered Benzo-Fused Sultams |
Q48370410 | Pd-Catalyzed Enantioselective [6+4] Cycloaddition of Vinyl Oxetanes with Azadienes to Access Ten-Membered Heterocycles |
Q55535124 | Peptidines: glycine-amidine-based oligomers for solution- and solid-phase synthesis† †Electronic supplementary information (ESI) available: Experimental procedures, characterization data of new compounds. CCDC 1430515. For ESI and crystallographic d |
Q35548736 | Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries |
Q36231032 | Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings |
Q51743864 | Radical-Mediated 1,2-Formyl/Carbonyl Functionalization of Alkenes and Application to the Construction of Medium-Sized Rings. |
Q30490492 | Ring-Expansion Approach to Medium-Sized Lactams and Analysis of Their Medicinal Lead-Like Properties |
Q39179647 | Ring-Expansion Reactions in the Synthesis of Macrocycles and Medium-Sized Rings |
Q53085414 | Selective synthesis of three product classes from imine and carboxylic acid precursors via direct imine acylation. |
Q38918833 | Seven-membered rings through metal-free rearrangement mediated by hypervalent iodine. |
Q48100654 | Structurally diverse arene-fused ten-membered lactams accessed via hydrolytic imidazoline ring expansion. |
Q89220527 | Synthesis of Benzannulated Medium-ring Lactams via a Tandem Oxidative Dearomatization-Ring Expansion Reaction |
Q48103688 | Synthesis of Cyclic Peptide Mimetics by the Successive Ring Expansion of Lactams. |
Q43762423 | Total Synthesis of Terpenoids Employing a "Benzannulation of Carvone" Strategy: Synthesis of (-)-Crotogoudin. |
Q48144026 | Traceless Solid-Phase Synthesis of Fused Chiral Macrocycles via Conformational Constraint-Assisted Cyclic Iminium Formation. |
Q50576686 | Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings. |
Search more.