Making digit patterns in the vertebrate limb

scientific article

Making digit patterns in the vertebrate limb is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1048044829
P356DOI10.1038/NRM1830
P698PubMed publication ID16493412
P5875ResearchGate publication ID7284675

P50authorCheryll TickleQ5092805
P2860cites workHedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limbQ22253250
A global control region defines a chromosomal regulatory landscape containing the HoxD clusterQ24301317
Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndromeQ24314959
Hox10 and Hox11 genes are required to globally pattern the mammalian skeletonQ28188034
A gradient of gap junctional communication along the anterior-posterior axis of the developing chick limb budQ67763826
A quantitative analysis of the effect of all-trans-retinoic acid on the pattern of chick wing developmentQ70087993
Region-specific expression of mario reveals pivotal function of the anterior nondigit region on digit formation in chick wing budQ81649928
The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptidesQ28209351
Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog functionQ28209365
A re-examination of proximodistal patterning during vertebrate limb developmentQ28216626
The roles of FGFs in the early development of vertebrate limbsQ28273288
Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identitiesQ28277481
Expression of the homeobox Hox-4 genes and the specification of position in chick wing developmentQ28322610
Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterningQ28504770
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesisQ28506504
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factorsQ28509134
Hedgehog signalling in the mouse requires intraflagellar transport proteinsQ28593010
A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tubeQ28593188
Sonic hedgehog mediates the polarizing activity of the ZPAQ29616565
Positional information and the spatial pattern of cellular differentiationQ29616635
Developmental basis of evolutionary digit loss in the Australian lizard Hemiergis.Q30980087
Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.Q33877368
Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identityQ34146314
Finger or toe: the molecular basis of limb identityQ34281744
Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wingQ34301558
Pattern formation in the Drosophila wing: The development of the veinsQ35115825
Interdigital regulation of digit identity and homeotic transformation by modulated BMP signalingQ39542358
Gene expression and digit homology in the chicken embryo wing.Q39704693
Positional Information in Chick Limb MorphogenesisQ39955273
A freely diffusible form of Sonic hedgehog mediates long-range signallingQ40800630
Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformationsQ41089950
A dual role for Hox genes in limb anterior-posterior asymmetryQ47358694
Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function.Q52046374
Tbx3 can alter limb position along the rostrocaudal axis of the developing embryo.Q52054111
Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling.Q52095015
Fgf signaling controls the number of phalanges and tip formation in developing digits.Q52099058
Regulation of Tbx3 expression by anteroposterior signalling in vertebrate limb development.Q52113875
Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.Q52115170
Expression pattern of Irx1 and Irx2 during mouse digit development.Q52132021
Cloning and expression of CSAL2, a new member of the spalt gene family in chick.Q52137252
Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing.Q52201470
The fate map of the chick forelimb-bud and its bearing on hypothesized developmental control mechanisms.Q52247848
Positional signal transmission in the developing chick limbQ52532522
Positional signalling and specification of digits in chick limb morphogenesisQ59053495
Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formationQ59065602
Cell cycle and experimental pattern duplication in the chick wing during embryonic developmentQ59079304
The number of polarizing region cells required to specify additional digits in the developing chick wingQ59080132
Positional signalling by mouse limb polarising region in the chick wing budQ67436461
P433issue1
P304page(s)45-53
P577publication date2006-01-01
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleMaking digit patterns in the vertebrate limb
P478volume7

Reverse relations

cites work (P2860)
Q518698633D expression patterns of cell cycle genes in the developing chick wing and comparison with expression patterns of genes implicated in digit specification.
Q27334063A computational clonal analysis of the developing mouse limb bud
Q61798480A novel truncating variant of GLI2 associated with Culler-Jones syndrome impairs Hedgehog signalling
Q97891555A quantitative modelling approach to zebrafish pigment pattern formation
Q33810026A regulatory network of two galectins mediates the earliest steps of avian limb skeletal morphogenesis.
Q34948656A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning
Q46683907AP-2β is a transcriptional regulator for determination of digit length in tetrapods.
Q50680458Altered developmental events in the anterior region of the chick forelimb give rise to avian-specific digit loss.
Q34575070BMP-mediated functional cooperation between Dlx5;Dlx6 and Msx1;Msx2 during mammalian limb development
Q36145986Beyond the French Flag Model: Exploiting Spatial and Gene Regulatory Interactions for Positional Information
Q30053873Biased Polyphenism in Polydactylous Cats Carrying a Single Point Mutation: The Hemingway Model for Digit Novelty
Q50656386Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice.
Q86061403Can we regrow a human arm? A negative perspective from an upper-limb surgeon
Q37938702Cartilage biology in osteoarthritis--lessons from developmental biology
Q38119136Central and ulnar cleft hands: a review of concurrent deformities in a series of 47 patients and their pathogenesis
Q28302606Cilia and developmental signaling
Q35022641Cilia involvement in patterning and maintenance of the skeleton
Q34375182Cross-sectional data on soft tissue morphometry of the growing hand and fingers of dextral individuals 5-65 years old.
Q37526818Crosstalk between Wnt and bone morphogenic protein signaling: a turbulent relationship
Q37201726Developmental expression of retinoic acid receptors (RARs).
Q36819798Dynamic changes after murine digit amputation: the MRL mouse digit shows waves of tissue remodeling, growth, and apoptosis
Q33545486Ectodermal Wnt6 is an early negative regulator of limb chondrogenesis in the chicken embryo
Q38168392Embryology of familial (non-syndromic) brachydactyly of the hand
Q39557934Embryonic development of the fossorial gymnophthalmid lizards Nothobachia ablephara and Calyptommatus sinebrachiatus
Q37940373Epiphyseal growth plate and secondary peripheral chondrosarcoma: the neighbours matter.
Q44465765Estimating the spatiotemporal pattern of volumetric growth rate from fate maps in chick limb development
Q33825531Evolution of vertebrate appendicular structures: Insight from genetic and palaeontological data
Q59797988Expression analysis of limb element markers during mouse embryonic development
Q36892599Extrinsic versus intrinsic cues in avian paraxial mesoderm patterning and differentiation.
Q42515258Fibroblast cluster formation on 3D collagen matrices requires cell contraction dependent fibronectin matrix organization.
Q26852935Fibroblast morphogenesis on 3D collagen matrices: the balance between cell clustering and cell migration
Q26744669Functional Zonation of the Adult Mammalian Adrenal Cortex
Q39146281GLI3-related polydactyly: a review
Q28592864Generation of mice with functional inactivation of talpid3, a gene first identified in chicken
Q37779763Genetic and pathologic aspects of retinoic acid-induced limb malformations in the mouse
Q37704380Hedgehog and Wnt coordinate signaling in myogenic progenitors and regulate limb regeneration
Q24294800IHH and FGF8 coregulate elongation of digit primordia
Q28592776Identification and analysis of a conserved Tcfap2a intronic enhancer element required for expression in facial and limb bud mesenchyme
Q36545326Imparting regenerative capacity to limbs by progenitor cell transplantation
Q87703358Involvement and alteration of the Sonic Hedgehog pathway is associated with decreased cholesterol level in trisomy 18 and SLO amniocytes
Q36792546Keratinocyte-fibroblast interactions in wound healing
Q45892791Mathematical modelling of digit specification by a sonic hedgehog gradient
Q34999630Mathematically guided approaches to distinguish models of periodic patterning
Q37845326Mechanisms of digit formation: Human malformation syndromes tell the story
Q47121122Mechanisms of urodele limb regeneration
Q28507114Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway
Q37036052Mutant Hoxd13 induces extra digits in a mouse model of synpolydactyly directly and by decreasing retinoic acid synthesis
Q42285297Neogenin regulates Sonic Hedgehog pathway activity during digit patterning
Q39953506Ofd1 is required in limb bud patterning and endochondral bone development
Q28260017Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly
Q44490937Optimal placement of multiple morphogen sources
Q36450140Orientation of Turing-like Patterns by Morphogen Gradients and Tissue Anisotropies
Q56485229Part-whole science
Q39162665Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog
Q38293317Radiological imaging of congenital hand anomalies--a 6-year single-centre experience and what the hand surgeons want to know
Q51522226Reaction-diffusion systems and external morphogen gradients: the two-dimensional case, with an application to skeletal pattern formation.
Q38753547Repeated removal of developing limb buds permanently reduces appendage size in the highly-regenerative axolotl
Q46549138Retinoic acid in development: towards an integrated view
Q30503298Retinoic acid signaling sequentially controls visceral and heart laterality in zebrafish
Q33430628Role of Genetic Factors in the Pathogenesis of Radial Deficiencies in Humans
Q39557927Skeletal development in the fossorial gymnophthalmids Calyptommatus sinebrachiatus and Nothobachia ablephara
Q45029905The Sonic hedgehog gradient in the developing limb
Q33593967The full-length unprocessed hedgehog protein is an active signaling molecule
Q29347242The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs.
Q51586911Transcriptomic analysis of avian digits reveals conserved and derived digit identities in birds.
Q37780028WNT pathways and upper limb anomalies
Q30589742Waves and patterning in developmental biology: vertebrate segmentation and feather bud formation as case studies
Q55362750Zone of Polarizing Activity Regulatory Sequence Mutations/Duplications with Preaxial Polydactyly and Longitudinal Preaxial Ray Deficiency in the Phenotype: A Review of Human Cases, Animal Models, and Insights Regarding the Pathogenesis.

Search more.