HSV-TK/GCV cancer suicide gene therapy by a designed recombinant multifunctional vector

scientific article published on October 1, 2010

HSV-TK/GCV cancer suicide gene therapy by a designed recombinant multifunctional vector is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.NANO.2010.08.003
P953full work available at URLhttps://europepmc.org/articles/pmc3024463?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20817124/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20817124/pdf/?tool=EBI
https://europepmc.org/articles/PMC3024463
https://europepmc.org/articles/PMC3024463?pdf=render
https://doi.org/10.1016/j.nano.2010.08.003
https://api.elsevier.com/content/article/PII:S1549963410002467?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1549963410002467?httpAccept=text/plain
P932PMC publication ID3024463
P698PubMed publication ID20817124
P5875ResearchGate publication ID46148487

P2093author name stringYuhua Wang
Arash Hatefi
Brenda F. Canine
P2860cites workBacterial Cytosine Deaminase Mutants Created by Molecular Engineering Show Improved 5-Fluorocytosine-Mediated Cell Killing In vitro and In vivoQ27655704
Characterization of herpes simplex virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activityQ33184179
Recombinant fusion proteins TAT-Mu, Mu and Mu-Mu mediate efficient non-viral gene deliveryQ33280618
Biosynthesis and characterization of a novel genetically engineered polymer for targeted gene transfer to cancer cellsQ34060541
A designer biomimetic vector with a chimeric architecture for targeted gene transferQ34078983
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The use of Fas Ligand, TRAIL and Bax in gene therapy of prostate cancer.Q34729437
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Designed multi-domain protein as a carrier of nucleic acids into cellsQ39927009
Rat adenocarcinoma cell line infected with an adenovirus carrying a novel herpes-simplex virus-thymidine kinase suicide gene construct dies by apoptosis upon treatment with ganciclovirQ40064944
Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells.Q40481710
Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosisQ40632272
Nuclear localisation sequence templated nonviral gene delivery vectors: investigation of intracellular trafficking events of LMD and LD vector systemsQ40659015
In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain TumorsQ42818740
Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killingQ43578068
Adenovirus-mediated gene transfer of enhanced Herpes simplex virus thymidine kinase mutants improves prodrug-mediated tumor cell killingQ43962720
Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapyQ45069710
A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.Q45739549
Enhanced ganciclovir killing and bystander effect of human tumor cells transduced with a retroviral vector carrying a herpes simplex virus thymidine kinase gene mutantQ45741033
Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma.Q45755851
Development of a genetically engineered biomimetic vector for targeted gene transfer to breast cancer cellsQ47871933
Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) geneQ64379934
A nuclear localization signal can enhance both the nuclear transport and expression of 1 kb DNAQ77789524
The effect of the structure of small cationic peptides on the characteristics of peptide-DNA complexesQ82748637
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectsuicideQ10737
gene therapyQ213901
P304page(s)193-200
P577publication date2010-10-01
P1433published inNanomedicine: Nanotechnology, Biology and MedicineQ6964073
P1476titleHSV-TK/GCV cancer suicide gene therapy by a designed recombinant multifunctional vector
P478volume7

Reverse relations

cites work (P2860)
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Q36534930Frontiers in Suicide Gene Therapy of Cancer
Q36592690Genetically engineered theranostic mesenchymal stem cells for the evaluation of the anticancer efficacy of enzyme/prodrug systems
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Q39139918Nicotinamide mononucleotide adenylyltransferase2 overexpression enhances colorectal cancer cell-kill by Tiazofurin
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