MyoD directly up-regulates premyogenic mesoderm factors during induction of skeletal myogenesis in stem cells.

scientific article

MyoD directly up-regulates premyogenic mesoderm factors during induction of skeletal myogenesis in stem cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.163709
P932PMC publication ID3024746
P698PubMed publication ID21078671

P50authorZizhen YaoQ55966299
P2093author name stringStephen J Tapscott
Ilona S Skerjanc
Anastassia Voronova
Yi Cao
Xiaonan Wang
Virja Mehta
Peter J Gianakopoulos
Josée Coutu
Michelle S Waddington
P2860cites workMyocyte enhancer factor 2C and Nkx2-5 up-regulate each other's expression and initiate cardiomyogenesis in P19 cellsQ22008552
Expression of the Mf1 gene in developing mouse hearts: implication in the development of human congenital heart defectsQ22010514
MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblastsQ24297101
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteinsQ24299387
The myoD Gene Family: Nodal Point During Specification of the Muscle Cell LineageQ24310740
A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblastsQ24339468
Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2CQ24647260
Altered myogenesis in Six1-deficient miceQ28187781
Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expressionQ28212702
Six and Eya expression during human somitogenesis and MyoD gene family activationQ28219080
Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerizationQ28239333
Differential roles of p300 and PCAF acetyltransferases in muscle differentiationQ28276083
Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivoQ28298865
Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and for each of the neurofilament triplet polypeptidesQ72722542
Myocyte enhancer factor 2C and myogenin up-regulate each other's expression and induce the development of skeletal muscle in P19 cellsQ73316712
Wnt signaling regulates the function of MyoD and myogeninQ74071519
CREB-binding protein/p300 activates MyoD by acetylationQ74177706
The C-terminus of myogenin, but not MyoD, targets upregulation of MEF2C expressionQ74505473
Factors in serum regulate muscle development in P19 cellsQ78229948
Homeobox genes and connective tissue patterningQ28300079
Control of dorsoventral somite patterning by Wnt-1 and beta-cateninQ28506672
MyoD or Myf-5 is required for the formation of skeletal muscleQ28510042
The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somitesQ28510603
Beta-catenin is essential and sufficient for skeletal myogenesis in P19 cellsQ28511049
Roles for the winged helix transcription factors MF1 and MFH1 in cardiovascular development revealed by nonallelic noncomplementation of null allelesQ28586665
An initial blueprint for myogenic differentiationQ28588060
Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotomeQ28588678
Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2CQ28589290
Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding siteQ28589912
Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tractQ28590442
The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryoQ28591300
Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin geneQ28592173
Eya1 and Eya2 proteins are required for hypaxial somitic myogenesis in the mouse embryoQ28592591
A role for WNT proteins in induction of dermomyotomeQ28593135
Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryoQ28593548
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse nodeQ28594387
Expression of a single transfected cDNA converts fibroblasts to myoblastsQ29547764
Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selectionQ29617433
Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix proteinQ29618504
Two distinct types of repression domain in engrailed: one interacts with the groucho corepressor and is preferentially active on integrated target genesQ33786539
Cardiac and skeletal muscle development in P19 embryonal carcinoma cellsQ33819926
Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formationQ33885274
Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modificationsQ33920801
Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specificationQ34108593
p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiationQ34124906
MyoD family: a paradigm for development?Q34271215
Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell lineQ34279058
Identification of novel MyoD gene targets in proliferating myogenic stem cellsQ34285149
Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.Q34290920
Cooperation between myogenic regulatory factors and SIX family transcription factors is important for myoblast differentiationQ34298160
Disruption of Meox or Gli activity ablates skeletal myogenesis in P19 cellsQ34308170
Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant miceQ34350930
Hedgehog signaling induces cardiomyogenesis in P19 cellsQ34406762
A Pax3/Pax7-dependent population of skeletal muscle progenitor cellsQ34412889
Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placodeQ34414173
Herculin, a fourth member of the MyoD family of myogenic regulatory genesQ34419943
Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD.Q34420945
MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancerQ34453492
Aberrant regulation of MyoD1 contributes to the partially defective myogenic phenotype of BC3H1 cellsQ36223014
MyoD induces myogenic differentiation through cooperation of its NH2- and COOH-terminal regions.Q36320492
Cellular aggregation enhances MyoD-directed skeletal myogenesis in embryonal carcinoma cellsQ36673004
Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD.Q37309344
Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesisQ37541258
Muscle-specific transcriptional activation by MyoDQ38334158
Control of somite patterning by Sonic hedgehog and its downstream signal response genesQ38338780
The MyoD DNA binding domain contains a recognition code for muscle-specific gene activationQ38341599
Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming.Q38344633
SOX15 and SOX7 differentially regulate the myogenic program in P19 cellsQ39844013
Differences between MyoD DNA binding and activation site requirements revealed by functional random sequence selectionQ40019388
Compartmentalization of the somite and myogenesis in chick embryos are influenced by wnt expressionQ40840940
Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites.Q40886200
Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.Q41080686
Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos.Q41102084
Skeletal muscle satellite cells appear during late chicken embryogenesisQ41481176
Determinants of myogenic specificity within MyoD are required for noncanonical E box bindingQ42412056
Pax7 and myogenic progression in skeletal muscle satellite cellsQ42493249
Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potentialQ42828894
Tissue-specific gene activation by MyoD: determination of specificity by cis-acting repression elementsQ42833957
Pax3/Pax7 mark a novel population of primitive myogenic cells during developmentQ42863008
Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal deathQ43409060
Pax3 is essential for skeletal myogenesis and the expression of Six1 and Eya2.Q43550249
Hedgehog and patched in neural development and diseaseQ44422812
Cross talk between hedgehog and bone morphogenetic proteins occurs during cardiomyogenesis in P19 cells.Q45936052
mef2c is activated directly by myogenic basic helix-loop-helix proteins during skeletal muscle development in vivoQ46055034
A common somitic origin for embryonic muscle progenitors and satellite cells.Q46448324
Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specificationQ46458507
Correct coordination of neuronal differentiation events in ventral forebrain requires the bHLH factor MASH1.Q47622357
A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice.Q48015661
Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesisQ48132703
Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoterQ48351986
Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation.Q52062326
Myocyte enhancer factor 2C upregulates MASH-1 expression and induces neurogenesis in P19 cells.Q52168870
Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5.Q52180274
Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development.Q52229612
Canonical Wnt signaling regulates Foxc1/2 expression in P19 cells.Q54463714
Differential response of satellite cells and embryonic myoblasts to a tumor promoter.Q54492947
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)2517-2525
P577publication date2010-11-15
P1433published inJournal of Biological ChemistryQ867727
P1476titleMyoD directly up-regulates premyogenic mesoderm factors during induction of skeletal myogenesis in stem cells
P478volume286

Reverse relations

cites work (P2860)
Q38301269AP-1-mediated expression of brain-specific class IVa β-tubulin in P19 embryonal carcinoma cells
Q33895175Ascl1/Mash1 is a novel target of Gli2 during Gli2-induced neurogenesis in P19 EC cells
Q36093041BRG1 interacts with GLI2 and binds Mef2c gene in a hedgehog signalling dependent manner during in vitro cardiomyogenesis
Q33991726Developmental transcriptome analysis of human erythropoiesis.
Q35588547Distant cis-regulatory elements in human skeletal muscle differentiation.
Q27324593Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro
Q48204589Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing.
Q39422264Gli2 and MEF2C activate each other's expression and function synergistically during cardiomyogenesis in vitro
Q39220900Hedgehog signaling regulates MyoD expression and activity
Q38834036Hedgehog/Patched-associated rhabdomyosarcoma formation from delta1-expressing mesodermal cells
Q33745860MYOD mediates skeletal myogenic differentiation of human amniotic fluid stem cells and regeneration of muscle injury
Q33854168Molecular ties between the cell cycle and differentiation in embryonic stem cells
Q36601884Myogenic Differentiation of Mouse Embryonic Stem Cells That Lack a Functional Pax7 Gene
Q92663085Serial Xenotransplantation in NSG Mice Promotes a Hybrid Epithelial/Mesenchymal Gene Expression Signature and Stemness in Rhabdomyosarcoma Cells
Q38184513Six1: a critical transcription factor in tumorigenesis
Q39321274Skeletal Muscle Cell Induction from Pluripotent Stem Cells
Q50002372Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine
Q39378020Sodium arsenite represses the expression of myogenin in C2C12 mouse myoblast cells through histone modifications and altered expression of Ezh2, Glp, and Igf-1.
Q40825206The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development.
Q38248282The role of Six1 in the genesis of muscle cell and skeletal muscle development
Q40637660Time course and side-by-side analysis of mesodermal, pre-myogenic, myogenic and differentiated cell markers in the chicken model for skeletal muscle formation
Q89500866Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors
Q34282979Transcriptome of Atoh7 retinal progenitor cells identifies new Atoh7-dependent regulatory genes for retinal ganglion cell formation
Q57462395Xenopus SOX5 enhances myogenic transcription indirectly through transrepression
Q28504791β-catenin is essential for efficient in vitro premyogenic mesoderm formation but can be partially compensated by retinoic acid signalling

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