The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess

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The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15252/EMBJ.201489468
P932PMC publication ID4232046
P698PubMed publication ID25092765
P5875ResearchGate publication ID264461319

P50authorErnst R WernerQ41776119
Masashi KatoQ56462176
Beatrix E LechnerQ59191820
Robert CramerQ59917212
Axel A BrakhageQ70220634
Hubertus HaasQ87841757
P2093author name stringDawoon Chung
Ulrich Mühlenhoff
Aaron A Vogan
Peter Hortschansky
Fabio Gsaller
Sarah R Beattie
Nicole Rietzschel
Katja Tuppatsch
Veronika Klammer
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Glutaredoxins Grx3 and Grx4 regulate nuclear localisation of Aft1 and the oxidative stress response in Saccharomyces cerevisiae.Q27932221
Assembly of the Hap2p/Hap3p/Hap4p/Hap5p-DNA complex in Saccharomyces cerevisiaeQ27934372
Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradationQ27934670
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A transcription factor cascade involving Fep1 and the CCAAT-binding factor Php4 regulates gene expression in response to iron deficiency in the fission yeast Schizosaccharomyces pombeQ40929049
Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur clusterQ41814139
Validation of a self-excising marker in the human pathogen Aspergillus fumigatus by employing the beta-rec/six site-specific recombination system.Q42428304
CGFS-type monothiol glutaredoxins from the cyanobacterium Synechocystis PCC6803 and other evolutionary distant model organisms possess a glutathione-ligated [2Fe-2S] clusterQ46877317
The Aspergillus nidulans GATA factor SREA is involved in regulation of siderophore biosynthesis and control of iron uptakeQ47988382
The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus.Q50487967
Deciphering correct strategies for multiprotein complex assembly by co-expression: application to complexes as large as the histone octamer.Q52715652
Efficient PCR-based gene targeting with a recyclable marker for Aspergillus nidulans.Q54631166
The genetics of Aspergillus nidulansQ62650991
HapX-mediated iron homeostasis is essential for rhizosphere competence and virulence of the soilborne pathogen Fusarium oxysporumQ84962450
Role of glutaredoxin-3 and glutaredoxin-4 in the iron regulation of the Aft1 transcriptional activator in Saccharomyces cerevisiaeQ27934787
Yap5 is an iron-responsive transcriptional activator that regulates vacuolar iron storage in yeastQ27939742
SreA-mediated iron regulation in Aspergillus fumigatusQ27976506
A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applicationsQ28213193
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteinsQ28254176
SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatusQ28478226
Oxygen toxicity, oxygen radicals, transition metals and diseaseQ29615096
Single-step affinity purification for fungal proteomics.Q30494334
Glutaredoxins: roles in iron homeostasisQ33636455
The CCAAT-binding complex coordinates the oxidative stress response in eukaryotesQ33700101
HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatusQ33716978
HapX positively and negatively regulates the transcriptional response to iron deprivation in Cryptococcus neoformansQ33760802
Activation of the iron regulon by the yeast Aft1/Aft2 transcription factors depends on mitochondrial but not cytosolic iron-sulfur protein biogenesisQ34384248
Genetic and biochemical analysis of high iron toxicity in yeast: iron toxicity is due to the accumulation of cytosolic iron and occurs under both aerobic and anaerobic conditionsQ34537045
Candida albicans Hap43 is a repressor induced under low-iron conditions and is essential for iron-responsive transcriptional regulation and virulenceQ34739217
Regulation of sulphur assimilation is essential for virulence and affects iron homeostasis of the human-pathogenic mould Aspergillus fumigatus.Q34979362
An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesisQ35190378
Yap5 protein-regulated transcription of the TYW1 gene protects yeast from high iron toxicityQ35515490
Iron - A Key Nexus in the Virulence of Aspergillus fumigatusQ35738573
Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by ironQ35880604
The monothiol glutaredoxin Grx4 exerts an iron-dependent inhibitory effect on Php4 functionQ36017860
An overview of the CCAAT-box binding factor in filamentous fungi: assembly, nuclear translocation, and transcriptional enhancement.Q36105336
Monothiol CGFS glutaredoxins and BolA-like proteins: [2Fe-2S] binding partners in iron homeostasisQ36250073
A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeastQ36318684
Chloroplast monothiol glutaredoxins as scaffold proteins for the assembly and delivery of [2Fe-2S] clusters.Q36570695
NF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factorsQ37061160
Post-transcriptional regulation of iron homeostasis in Saccharomyces cerevisiae.Q37139091
Siderophores in fungal physiology and virulenceQ37235289
Both Php4 function and subcellular localization are regulated by iron via a multistep mechanism involving the glutaredoxin Grx4 and the exportin Crm1.Q37339053
Rapid production of gene replacement constructs and generation of a green fluorescent protein-tagged centromeric marker in Aspergillus nidulansQ37579716
Iron acquisition and transcriptional regulationQ37586443
Iron uptake and regulation in Schizosaccharomyces pombe.Q38126719
xylP promoter-based expression system and its use for antisense downregulation of the Penicillium chrysogenum nitrogen regulator NRE.Q39488249
Iron regulation through the back door: iron-dependent metabolite levels contribute to transcriptional adaptation to iron deprivation in Saccharomyces cerevisiaeQ39605933
P433issue19
P407language of work or nameEnglishQ1860
P304page(s)2261-2276
P577publication date2014-08-04
P1433published inThe EMBO JournalQ1278554
P1476titleThe Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess
P478volume33

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