Characterization of distinct sub-cellular location of transglutaminase type II: changes in intracellular distribution in physiological and pathological states

scientific article

Characterization of distinct sub-cellular location of transglutaminase type II: changes in intracellular distribution in physiological and pathological states is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1040501818
P356DOI10.1007/S00441-014-1990-X
P932PMC publication ID4233112
P698PubMed publication ID25209703
P5875ResearchGate publication ID265557900

P50authorGiuseppe IppolitoQ28468788
Mauro PiacentiniQ30111905
Laura FalascaQ56334017
Manuela D'ElettoQ56334441
Carlo RodolfoQ56863263
P2093author name stringFranca Del Nonno
Maria Grazia Farrace
P2860cites workOverexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathwayQ24301518
Transglutaminase 2: an enigmatic enzyme with diverse functionsQ28205648
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Role of transglutaminase 2 in celiac disease pathogenesisQ28262529
The role of transglutaminase-2 and its substrates in human diseasesQ28287957
Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alphaQ28289207
The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrial-dependent apoptosisQ60687719
Inhibition of the formation of myotubes in vitro by inhibitors of transglutaminaseQ72697407
Distinct nuclear localization and activity of tissue transglutaminaseQ74516745
Transglutaminase 2 in the enterocytes is coeliac specific and gluten dependentQ80133681
Transglutaminase type II is involved in the pathogenesis of endotoxic shockQ80633659
Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfmentQ81767265
TG2 transamidating activity acts as a reostat controlling the interplay between apoptosis and autophagyQ83821836
Hyaluronic acid induces transglutaminase II to enhance cell motility; role of Rac1 and FAK in the induction of transglutaminase II.Q40097761
Implications of increased tissue transglutaminase (TG2) expression in drug-resistant breast cancer (MCF-7) cellsQ40322525
Phosphorylation of histones by tissue transglutaminase.Q40331106
Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stressQ40725013
Reduced expression of tissue transglutaminase in a human endothelial cell line leads to changes in cell spreading, cell adhesion and reduced polymerisation of fibronectin.Q41074541
Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteinsQ42064407
A role for transglutaminase in neurotransmitter release by rat brain synaptosomesQ42503358
Role of transglutaminase in [3H]5-HT release from synaptosomes and in the inhibitory effect of tetanus toxinQ42524286
Tissue transglutaminase is a multifunctional BH3-only proteinQ42638167
A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikisQ42802185
Bovine aortic endothelial cell transglutaminase. Enzyme characterization and regulation of activityQ42802854
Transglutaminase 2 is involved in autophagosome maturationQ43231650
Histone cross-linking by transglutaminaseQ44020953
The treatment of collagen fibrils by tissue transglutaminase to promote vascular smooth muscle cell contractile signaling.Q45916700
TGM2 is a novel marker for prognosis and therapeutic target in colorectal cancer.Q54448758
Role and predictive strength of transglutaminase type 2 expression in premalignant lesions of the cervix.Q54600809
Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomesQ33893946
Protein crosslinking in assembly and remodelling of extracellular matrices: the role of transglutaminasesQ33926887
Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activationQ34308397
Transglutaminases: crosslinking enzymes with pleiotropic functionsQ35058528
Role of tissue transglutaminase 2 in the acquisition of a mesenchymal-like phenotype in highly invasive A431 tumor cells.Q35147626
Histone modifiers in cancer: friends or foes?Q35216079
Transglutaminase 2 as an independent prognostic marker for survival of patients with non-adenocarcinoma subtype of non-small cell lung cancerQ35387117
At the crossroads of myocardial signaling: the role of Z-discs in intracellular signaling and cardiac function.Q35672020
Transglutaminase 2 facilitates the distant hematogenous metastasis of breast cancer by modulating interleukin-6 in cancer cellsQ35683575
Transglutaminase 2: a molecular Swiss army knifeQ35693361
Transglutaminase 2 is secreted from smooth muscle cells by transamidation-dependent microparticle formationQ35697155
Mammalian transglutaminases. Identification of substrates as a key to physiological function and physiopathological relevanceQ36019962
Transglutaminase 2 in the balance of cell death and survivalQ36156015
Specific fluorescent labeling of chicken myofibril Z-line proteins catalyzed by guinea pig liver transglutaminaseQ36200346
The role of tissue transglutaminase in cell-matrix interactionsQ36251149
Roles of transglutaminases in cardiac and vascular diseasesQ36664166
Transglutaminase and polyamination of tubulin: posttranslational modification for stabilizing axonal microtubulesQ36768195
Tissue transglutaminase and the stress responseQ36772428
Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1Q37124999
Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applicationsQ37316687
Bcl-2 family on guard at the ER.Q37412841
Covalent modifications of histones during mitosis and meiosis.Q37621183
Transglutaminase 2: a multi-functional protein in multiple subcellular compartmentsQ37690629
Regulation of autophagy in mammals and its interplay with apoptosis.Q37694356
Transglutaminase 2: a multi-tasking protein in the complex circuitry of inflammation and cancerQ37769807
Monitoring of transglutaminase 2 under different oxidative stress conditions.Q37909103
TG2, a novel extracellular protein with multiple functionsQ37912042
Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological rolesQ37973367
Transglutaminase 2 at the crossroads between cell death and survival.Q37973371
Nitric oxide regulates non-classical secretion of tissue transglutaminaseQ38865948
Increase in endoplasmic reticulum-associated tissue transglutaminase and enzymatic activation in a cellular model of Parkinson's diseaseQ39448529
Novel participation of transglutaminase-2 through c-Jun N-terminal kinase activation in sphingosylphosphorylcholine-induced keratin reorganization of PANC-1 cells.Q39490601
Up-regulation of fibronectin and tissue transglutaminase promotes cell invasion involving increased association with integrin and MMP expression in A431 cellsQ39637744
Degradation of transglutaminase 2 by calcium-mediated ubiquitination responding to high oxidative stressQ39888950
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P304page(s)793-805
P577publication date2014-09-11
P1433published inCell and Tissue ResearchQ1524113
P1476titleCharacterization of distinct sub-cellular location of transglutaminase type II: changes in intracellular distribution in physiological and pathological states
P478volume358

Reverse relations

cites work (P2860)
Q33442546Cre/lox Studies Identify Resident Macrophages as the Major Source of Circulating Coagulation Factor XIII-A.
Q48167266Dissecting the interaction between transglutaminase 2 and fibronectin
Q39273075Effect of Some Growth Factors on Tissue Transglutaminase Overexpression Induced by β-Amyloid in Olfactory Ensheathing Cells.
Q89621128Inhibition of Transglutaminase 2 as a Potential Host-Directed Therapy Against Mycobacterium tuberculosis
Q64917749Liver sinusoidal endothelial cells (LSECs) modifications in patients with chronic hepatitis C.
Q47767397Mutations in TGM6 induce the unfolded protein response in SCA35.
Q49959253Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2.
Q101411039Proteomics-informed identification of luminal targets for in situ diagnosis of inflammatory bowel disease
Q61806085Spotlight on the Transglutaminase 2-Heparan Sulfate Interaction
Q47730518Subcellular localization patterns of transglutaminase 2 in astrocytes and neurons are differentially altered by hypoxia
Q88645716TG2 regulates the heat-shock response by the post-translational modification of HSF1
Q64249805The Role of Tissue Transglutaminase in Cancer Cell Initiation, Survival and Progression
Q58064967Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies
Q38682039Transglutaminase 2 modulation of NF-κB signaling in astrocytes is independent of its ability to mediate astrocytic viability in ischemic injury
Q38746075Transglutaminase type 2 affects cell migration through post-translational modification of platelet-derived growth factor-BB.
Q47367907Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection.
Q92219315Transglutaminase-2 Mediates the Biomechanical Properties of the Colorectal Cancer Tissue Microenvironment that Contribute to Disease Progression
Q38937553Transglutaminase-2: evolution from pedestrian protein to a promising therapeutic target
Q26750714Where, How, and When: Positioning Posttranslational Modification Within Type 1 Diabetes Pathogenesis

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