Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production.

scientific article

Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production. is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID12124317

P50authorMichael S. TorbensonQ106615136
P2093author name stringYoung H Ko
Peter L Pedersen
Jean-Francois H Geschwind
Carolyn Magee
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectliver cancerQ623031
P304page(s)3909-3913
P577publication date2002-07-01
P1433published inCancer ResearchQ326097
P1476titleNovel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production
P478volume62

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cites work (P2860)
Q389466443-Bromopyruvate induces rapid human prostate cancer cell death by affecting cell energy metabolism, GSH pool and the glyoxalase system.
Q349937133-Bromopyruvate inhibits human gastric cancer tumor growth in nude mice via the inhibition of glycolysis
Q379806973-bromopyruvate: Targets and outcomes
Q36372328A Novel Inherently Radiopaque Bead for Transarterial Embolization to Treat Liver Cancer - A Pre-clinical Study
Q92082272ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients
Q37158312Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II.
Q47604904An essential role for IGF2 in cartilage development and glucose metabolism during postnatal long bone growth.
Q41947562Angiogenesis in rabbit hepatic tumor after transcatheter arterial embolization
Q36693454Angiotensin II increases gene expression after selective intra-arterial adenovirus delivery in a rabbit model assessed using in vivo SSTR2-based reporter imaging
Q64067410Apigenin and hesperidin augment the toxic effect of doxorubicin against HepG2 cells
Q35111997Assessment of Tumoricidal Efficacy and Response to Treatment with18F-FDG PET/CT After Intraarterial Infusion with the Antiglycolytic Agent 3-Bromopyruvate in the VX2 Model of Liver Tumor
Q44908249Best supportive care of hepatocellular carcinoma
Q35075838C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia
Q43066128Cancer abolishes the tissue type-specific differences in the phenotype of energetic metabolism.
Q55317070Cancer and Exercise: Warburg Hypothesis, Tumour Metabolism and High-Intensity Anaerobic Exercise.
Q27013632Cancer cell metabolism: implications for therapeutic targets
Q34509607Cellular ATP Synthesis Mediated by Type III Sodium-dependent Phosphate Transporter Pit-1 Is Critical to Chondrogenesis
Q39262718Citrate kills tumor cells through activation of apical caspases
Q28480562Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis
Q41317851Comparison of two different methods for inoculating VX2 tumors in rabbit livers and hind limbs.
Q36577658Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells
Q28079559Drugging the addict: non-oncogene addiction as a target for cancer therapy
Q39542687Dynamic scenario of metabolic pathway adaptation in tumors and therapeutic approach
Q36342034EPR oxygen imaging and hyperpolarized 13C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3‐bromopyruvate
Q38863836Effect of 3-bromopyruvate and atovaquone on infection during in vitro interaction of Toxoplasma gondii and LLC-MK2 cells.
Q39398652Effect of the antitumoral alkylating agent 3-bromopyruvate on mitochondrial respiration: role of mitochondrially bound hexokinase
Q36512795Effective Elimination of Cancer Stem Cells By a Novel Drug Combination Strategy
Q35052021Emerging metabolic targets in cancer therapy
Q37063643FDG-PET for evaluating the antitumor effect of intraarterial 3-bromopyruvate administration in a rabbit VX2 liver tumor model
Q39399488Flow cytometric evaluation of the effects of 3-bromopyruvate (3BP) and dichloracetate (DCA) on THP-1 cells: a multiparameter analysis
Q38042261Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma
Q39490136Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo.
Q34722614Hepatic arterial embolization with doxorubicin-loaded superabsorbent polymer microspheres in a rabbit liver tumor model.
Q36377949Hepatocellular carcinoma: therapy and prevention
Q33880100Hexokinase II inhibitor, 3-BrPA induced autophagy by stimulating ROS formation in human breast cancer cells
Q24595940Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
Q64093565Hexokinase-II Inhibition Synergistically Augments the Anti-tumor Efficacy of Sorafenib in Hepatocellular Carcinoma
Q46501130Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes.
Q37921677Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death.
Q37627652Interventional oncology: new options for interstitial treatments and intravascular approaches: targeting tumor metabolism via a loco-regional approach: a new therapy against liver cancer
Q41681638Intra-arterial Targeted Islet-specific Expression of Sirt1 Protects β Cells From Streptozotocin-induced Apoptosis in Mice
Q89995159Intracellular ATP levels influence cell fates in Dictyostelium discoideum differentiation
Q34432306Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism
Q35987880Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer
Q35213377Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis
Q26795759Metabolic interplay between glycolysis and mitochondrial oxidation: The reverse Warburg effect and its therapeutic implication
Q35506699Metabolic perturbation sensitizes human breast cancer to NK cell-mediated cytotoxicity by increasing the expression of MHC class I chain-related A/B
Q36733720Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II.
Q37431693Mitochondria and cancer
Q39491915Mitochondrial dysfunction and effect of antiglycolytic bromopyruvic acid in GL15 glioblastoma cells.
Q28548517Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells
Q28534587New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells
Q34769352Noninvasive Assessment of Gene Transfer and Expression by In Vivo Functional and Morphologic Imaging in a Rabbit Tumor Model
Q35801521PPARγ contributes to PKM2 and HK2 expression in fatty liver
Q35167406Perfusion CT Assessment of Tissue Hemodynamics Following Hepatic Arterial Infusion of Increasing Doses of Angiotensin II in a Rabbit Liver Tumor Model
Q38542150Pheochromocytoma: Gasping for Air.
Q46013875Preclinical Benefit of Hypoxia-Activated Intra-arterial Therapy with Evofosfamide in Liver Cancer.
Q39445595Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy
Q24618782Purinergic signalling and cancer
Q38165746Purinergic signalling in the liver in health and disease
Q34672595Rabbit hepatic arterial anatomy variations: implications on experimental design.
Q39907305Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells : ROS-mediated cell death by 3-BrPA.
Q26852150Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study
Q41587732Simultaneous delivery of Paclitaxel and Bcl-2 siRNA via pH-Sensitive liposomal nanocarrier for the synergistic treatment of melanoma
Q39972485Specificity of the anti-glycolytic activity of 3-bromopyruvate confirmed by FDG uptake in a rat model of breast cancer.
Q34834980Systemic administration of 3-bromopyruvate reveals its interaction with serum proteins in a rat model
Q38946885Systemic delivery of microencapsulated 3-bromopyruvate for the therapy of pancreatic cancer
Q37983497Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug
Q36687966Targeting glucose metabolism in cancer: new class of agents for loco-regional and systemic therapy of liver cancer and beyond?
Q39418495Targeting glycolysis in leukemia: a novel inhibitor 3-BrOP in combination with rapamycin
Q37384240Targeting of VX2 rabbit liver tumor by selective delivery of 3-bromopyruvate: a biodistribution and survival study
Q37461264The Genome-Wide Expression Profile of l,2,3,4,6-Penta-O-Galloyl-β-D-Glucose-Treated MDA-MB-231 Breast Cancer Cells: Molecular Target on Cancer Metabolism
Q33846541The P2Y2 nucleotide receptor mediates the proliferation and migration of human hepatocellular carcinoma cells induced by ATP.
Q34580081The Warburg effect and its cancer therapeutic implications
Q27025749The Warburg effect revisited--lesson from the Sertoli cell
Q38837920The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside.
Q37406500The antitumor effect and hepatotoxicity of a hexokinase II inhibitor 3-bromopyruvate: in vivo investigation of intraarterial administration in a rabbit VX2 hepatoma model.
Q34607831The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil
Q28296259The cancer cell's "power plants" as promising therapeutic targets: an overview
Q39648449The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma
Q26997789The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer
Q48560205The energy blockers 3-bromopyruvate and lonidamine: effects on bioenergetics of brain mitochondria
Q39858276The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis
Q38039421The scarlet letter of alkylation: a mini review of selective alkylating agents.
Q62663288Transport and cytotoxicity of the anticancer drug 3-bromopyruvate in the yeast Saccharomyces cerevisiae
Q37436821Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate
Q64055907Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment
Q38168262Tumor glycolysis as a target for cancer therapy: progress and prospects
Q34185914Tumor uptake of hollow gold nanospheres after intravenous and intra-arterial injection: PET/CT study in a rabbit VX2 liver cancer model.
Q37225440Uncovering the role of VDAC in the regulation of cell life and death
Q28249524Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen
Q88139059[Monocarboxylate transporter 1 enhances the sensitivity of breast cancer cells to 3-bromopyruvate in vitro]

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