| scholarly article | Q13442814 |
| P50 | author | Vadivel Ganapathy | Q43100758 |
| P2093 | author name string | Muthusamy Thangaraju | |
| Puttur D Prasad | |||
| Selvakumar Elangovan | |||
| Elangovan Gopal | |||
| Shiro Itagaki | |||
| Senthil K Karunakaran | |||
| P2860 | cites work | Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria | Q24595940 |
| SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers | Q24679642 | ||
| On the Origin of Cancer Cells | Q27861025 | ||
| Clinical development of histone deacetylase inhibitors as anticancer agents | Q28244438 | ||
| Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids | Q28245395 | ||
| Oxidative metabolism in cancer growth | Q28246480 | ||
| Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract | Q28284748 | ||
| SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter | Q28288590 | ||
| Why do cancers have high aerobic glycolysis? | Q28290710 | ||
| The cancer cell's "power plants" as promising therapeutic targets: an overview | Q28296259 | ||
| Causes and consequences of tumour acidity and implications for treatment | Q33818730 | ||
| Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP. | Q34355664 | ||
| The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism. | Q34490597 | ||
| Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase | Q34517998 | ||
| Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production. | Q34525433 | ||
| Cancer's molecular sweet tooth and the Warburg effect. | Q34566915 | ||
| Histone deacetylases and cancer: causes and therapies | Q34570082 | ||
| The Warburg effect and its cancer therapeutic implications | Q34580081 | ||
| SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases | Q34592763 | ||
| Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond | Q34875637 | ||
| DNA methyltransferase inhibitors-state of the art. | Q34990742 | ||
| Recently elucidated energy catabolism pathways provide opportunities for novel treatments in hepatocellular carcinoma | Q35782945 | ||
| Sodium-coupled monocarboxylate transporters in normal tissues and in cancer | Q37150883 | ||
| Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. | Q39940490 | ||
| Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer | Q39956798 | ||
| Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy | Q39975837 | ||
| Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231. | Q40136574 | ||
| Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8). | Q40275023 | ||
| Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family | Q42268126 | ||
| Modification of human erythrocyte pyruvate kinase by an active site-directed reagent: bromopyruvate | Q43934710 | ||
| The human tumour suppressor gene SLC5A8 expresses a Na+-monocarboxylate cotransporter | Q44848256 | ||
| Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate | Q45025022 | ||
| Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor | Q46696439 | ||
| Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma | Q53562189 | ||
| Intraarterial Therapy with a New Potent Inhibitor of Tumor Metabolism (3-bromopyruvate): Identification of Therapeutic Dose and Method of Injection in an Animal Model of Liver Cancer | Q60531739 | ||
| P433 | issue | 20 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4655-4666 | |
| P577 | publication date | 2009-10-01 | |
| P1433 | published in | Cancer | Q326041 |
| P1476 | title | Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate | |
| P478 | volume | 115 |
| Q35879138 | 3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants. |
| Q50253921 | 3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects |
| Q39383204 | Aerosolized 3-Bromopyruvate Inhibits Lung Tumorigenesis without Causing Liver Toxicity |
| Q42430494 | Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases |
| Q42317480 | Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications |
| Q39399488 | Flow cytometric evaluation of the effects of 3-bromopyruvate (3BP) and dichloracetate (DCA) on THP-1 cells: a multiparameter analysis |
| Q36592479 | Gene silencing of SLC5A8 identified by genome-wide methylation profiling in lung cancer |
| Q39317923 | Glutamine Deprivation Enhances Antitumor Activity of 3-Bromopyruvate through the Stabilization of Monocarboxylate Transporter-1 |
| Q37323297 | Helicobacter pylori Infection Is Associated with Decreased Expression of SLC5A8, a Cancer Suppressor Gene, in Young Children |
| Q39527421 | Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8). |
| Q26781239 | Intestinal Microbiota and the Innate Immune System - A Crosstalk in Crohn's Disease Pathogenesis |
| Q36489907 | MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors |
| Q53322611 | Metabolic targeting of oncogene MYC by selective activation of the proton-coupled monocarboxylate family of transporters |
| Q35661981 | Metabolism as a key to histone deacetylase inhibition |
| Q90007648 | Microbial osteoporosis: The interplay between the gut microbiota and bones via host metabolism and immunity |
| Q38165142 | Monocarboxylic acid transport |
| Q37763104 | Recently identified and potential targets for colon cancer treatment. |
| Q35118915 | Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. |
| Q36120919 | SLC5A8 Nuclear Translocation and Loss of Expression are Associated With Poor Outcome in Pancreatic Ductal Adenocarcinoma |
| Q55349805 | Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis. |
| Q37950461 | Strategies for therapy of retinal diseases using systemic drug delivery: relevance of transporters at the blood–retinal barrier |
| Q38872235 | Taming Tumor Glycolysis and Potential Implications for Immunotherapy |
| Q37983497 | Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug |
| Q37229190 | Targeting the Metabolic Microenvironment of Tumors |
| Q38837920 | The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside. |
| Q34305760 | The central role of the gut microbiota in chronic inflammatory diseases |
| Q38914134 | The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH. |
| Q64055907 | Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment |
| Q91717473 | Tumour Expression of Histone Deacetylases in Uveal Melanoma |
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