scholarly article | Q13442814 |
P2093 | author name string | Evgeny Edovitsky | |
Eyal Zcharia | |||
Michael Elkin | |||
Tamar Peretz | |||
Israel Vlodavsky | |||
Immanuel Lerner | |||
P2860 | cites work | Human heparanase. Purification, characterization, cloning, and expression | Q22003728 |
Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis | Q22010222 | ||
Heparanase mediates cell adhesion independent of its enzymatic activity | Q24303492 | ||
Processing and activation of latent heparanase occurs in lysosomes | Q24338680 | ||
Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis | Q24630993 | ||
A system for stable expression of short interfering RNAs in mammalian cells | Q27860875 | ||
Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis | Q28138868 | ||
Cloning and functional expression of a human heparanase gene | Q28139582 | ||
Heparanase expression in primary and metastatic pancreatic cancer | Q28201783 | ||
Heparanases and tumor metastasis | Q28294717 | ||
Macromolecular organization of basement membranes | Q28297954 | ||
Heparanase regulates murine hair growth | Q28511958 | ||
MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data | Q29547902 | ||
Functions of cell surface heparan sulfate proteoglycans | Q29618521 | ||
Basement membranes: structure, assembly and role in tumour angiogenesis | Q29622882 | ||
Extracellular matrix moieties, cytokines, and enzymes: dynamic effects on immune cell behavior and inflammation. | Q33835592 | ||
Delayed type hypersensitivity: current theories with an historic perspective | Q33836893 | ||
Molecular properties and involvement of heparanase in cancer progression and normal development | Q34088794 | ||
Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis | Q34098843 | ||
Heparanase: a key enzyme involved in cell invasion | Q34183747 | ||
A disaccharide that inhibits tumor necrosis factor alpha is formed from the extracellular matrix by the enzyme heparanase | Q34285445 | ||
Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis | Q34328744 | ||
Endothelium in vitro: a review of human vascular endothelial cell lines for blood vessel-related research | Q34503665 | ||
Degradation of heparan sulfate in the subendothelial extracellular matrix by a readily released heparanase from human neutrophils. Possible role in invasion through basement membranes | Q34557357 | ||
Suppression of experimental autoimmune diseases and prolongation of allograft survival by treatment of animals with low doses of heparins | Q34567626 | ||
The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule | Q34620069 | ||
Syndecans in inflammation | Q35094731 | ||
Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation | Q35382754 | ||
Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis | Q35745865 | ||
Extracellular sequestration and release of fibroblast growth factor: a regulatory mechanism? | Q37407186 | ||
Permanent cell line expressing human factor VIII-related antigen established by hybridization | Q37615209 | ||
Inhibition of tumor metastasis by heparanase inhibiting species of heparin. | Q38313060 | ||
Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents | Q39799215 | ||
Heparanase accelerates wound angiogenesis and wound healing in mouse and rat models. | Q40464583 | ||
Inflammatory cytokines and fatty acids regulate endothelial cell heparanase expression | Q40562955 | ||
Regulation of heparanase gene expression by estrogen in breast cancer. | Q40604115 | ||
Proteoglycans of basement membranes | Q40910738 | ||
Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function | Q40981990 | ||
Soluble antigen induces T lymphocytes to secrete an endoglycosidase that degrades the heparan sulfate moiety of subendothelial extracellular matrix | Q43769417 | ||
The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones | Q44317052 | ||
Undersulfated and glycol-split heparins endowed with antiangiogenic activity | Q44754685 | ||
Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior | Q44760488 | ||
Inhibition of T lymphocyte heparanase by heparin prevents T cell migration and T cell-mediated immunity | Q44887841 | ||
Effect of locally administered heparins on delayed-type hypersensitivity reactions | Q44896345 | ||
Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting | Q45221614 | ||
Enhanced delivery of naked DNA to the skin by non-invasive in vivo electroporation | Q45888962 | ||
Microarray analysis of primary endothelial cells challenged with different inflammatory and immune cytokines | Q46629210 | ||
Expression pattern and secretion of human and chicken heparanase are determined by their signal peptide sequence | Q48362166 | ||
Heavy functions for light chains. | Q52011907 | ||
Vascular endothelial cells in cell-mediated immunity: adoptive transfer with in vitro conditioned cells is genetically restricted at the endothelial cell barrier. | Q54281478 | ||
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis. | Q54705410 | ||
Evidence that sulphated polysaccharides inhibit tumour metastasis by blocking tumour-cell-derived heparanases | Q69423635 | ||
Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis | Q70986448 | ||
Inhibition of delayed-type hypersensitivity by heparin depleted of anticoagulant activity | Q71097183 | ||
Comparative analysis of the ability of leucocytes, endothelial cells and platelets to degrade the subendothelial basement membrane: evidence for cytokine dependence and detection of a novel sulfatase | Q72349595 | ||
Processing of the human heparanase precursor and evidence that the active enzyme is a heterodimer | Q73066556 | ||
Heparanase as mediator of angiogenesis: mode of action | Q74101720 | ||
Heparanase protein and gene expression in bladder cancer | Q74486083 | ||
Heparanase-1 expression is associated with the metastatic potential of breast cancer | Q74758098 | ||
The pure antiestrogen ICI 182,780 inhibits progestin-induced transcription | Q77931882 | ||
[Studies on hypersensitivity. I. Demonstration and description of an increase of vascular permeability in the tuberculin hypersensitivity reactions] | Q79701133 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | endothelium | Q111140 |
P304 | page(s) | 3609-3616 | |
P577 | publication date | 2005-12-29 | |
P1433 | published in | Blood | Q885070 |
P1476 | title | Role of endothelial heparanase in delayed-type hypersensitivity | |
P478 | volume | 107 |
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Q45977912 | Chronological changes of delayed-type hypersensitivity in mice immunised with testicular germ cells alone. |
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