Green tea polyphenols reduced fat deposits in high fat-fed rats via erk1/2-PPARγ-adiponectin pathway (scientific article)

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P275

Creative Commons Attribution 4.0 International

copyrighted

issue

language of work or name

English

Q1860

P921

main subject

polyphenol

Q290439

tea

Q6097

P304

page(s)

e53796

P577

publication date

2013-01-15

P1433

published in

PLOS One

Q564954

P1476

title

Green tea polyphenols reduced fat deposits in high fat-fed rats via erk1/2-PPARγ-adiponectin pathway

P478

volume

Reverse relations

cites work (P2860)

Q39111404	Altered Transport and Metabolism of Phenolic Compounds in Obesity and Diabetes: Implications for Functional Food Development and Assessment.
Q28071627	At the interface of antioxidant signalling and cellular function: Key polyphenol effects
Q37392758	CDK5 promotes renal tubulointerstitial fibrosis in diabetic nephropathy via ERK1/2/PPARγ pathway
Q40222022	Cacao polyphenols ameliorate autoimmune myocarditis in mice
Q38270746	Can metabolically healthy obesity be explained by diet, genetics, and inflammation?
Q26861363	Cell Systems to Investigate the Impact of Polyphenols on Cardiovascular Health
Q38521024	Dietary polyphenols against metabolic disorders: How far have we progressed in the understanding of the molecular mechanisms of action of these compounds?
Q92661671	Effects and Mechanisms of Tea for the Prevention and Management of Diabetes Mellitus and Diabetic Complications: An Updated Review
Q35116119	Effects of green tea extract on insulin resistance and glucagon-like peptide 1 in patients with type 2 diabetes and lipid abnormalities: a randomized, double-blinded, and placebo-controlled trial
Q58605286	Effects of green tea extract on overweight and obese women with high levels of low density-lipoprotein-cholesterol (LDL-C): a randomised, double-blind, and cross-over placebo-controlled clinical trial
Q36015716	Environmentally Relevant Dose of Bisphenol A Does Not Affect Lipid Metabolism and Has No Synergetic or Antagonistic Effects on Genistein's Beneficial Roles on Lipid Metabolism
Q35832166	Green Tea Extract Rich in Epigallocatechin-3-Gallate Prevents Fatty Liver by AMPK Activation via LKB1 in Mice Fed a High-Fat Diet
Q41167278	Green tea extract induces genes related to browning of white adipose tissue and limits weight-gain in high energy diet-fed rat.
Q41255108	Green tea polyphenol treatment attenuates atherosclerosis in high-fat diet-fed apolipoprotein E-knockout mice via alleviating dyslipidemia and up-regulating autophagy.
Q46988821	Habitual consumption of coffee and green tea in relation to serum adipokines: a cross-sectional study
Q91654496	In silico analysis of antidiabetic potential of phenolic compounds from blue corn (Zea mays L.) and black bean (Phaseolus vulgaris L.).
Q92875863	Influence of Olive Extracts on the Expression of Genes Involved in Lipid Metabolism in Medaka Fish
Q42282446	Maternal intake of grape seed procyanidins during lactation induces insulin resistance and an adiponectin resistance-like phenotype in rat offspring
Q37191157	Mechanisms of body weight reduction and metabolic syndrome alleviation by tea.
Q26745587	Modulation of PPAR Expression and Activity in Response to Polyphenolic Compounds in High Fat Diets
Q33852218	Modulatory Effects of Guarana (Paullinia cupana) on Adipogenesis
Q38976864	Molecular mechanisms of the anti-obesity effect of bioactive compounds in tea and coffee
Q38231266	Molecular promiscuity of plant polyphenols in the management of age-related diseases: far beyond their antioxidant properties
Q37588979	Novel insights of dietary polyphenols and obesity
Q34038044	Oxidative stress and metabolic pathologies: from an adipocentric point of view.
Q26766508	Plants with potential use on obesity and its complications
Q39298312	Polyphenols and Their Role in Obesity Management: A Systematic Review of Randomized Clinical Trials
Q50980737	Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity.
Q92309662	The Bioprotective Effects of Polyphenols on Metabolic Syndrome against Oxidative Stress: Evidences and Perspectives
Q50445171	The anti-obesity effect of green tea polysaccharides, polyphenols and caffeine in rats fed with a high-fat diet.
Q53750139	The combined action of omega-3 polyunsaturated fatty acids and grape proanthocyanidins on a rat model of diet-induced metabolic alterations.
Q43119667	The effects of green tea on obesity and type 2 diabetes
Q36127934	The impact of polyphenols on chondrocyte growth and survival: a preliminary report
Q38904568	Therapeutic potential of green tea on risk factors for type 2 diabetes in obese adults - a review.

P819	ADS bibcode	2013PLoSO...853796T
P356	DOI	10.1371/JOURNAL.PONE.0053796
P932	PMC publication ID	3546082
P698	PubMed publication ID	23342006
P5875	ResearchGate publication ID	235364361