| scholarly article | Q13442814 |
| P2093 | author name string | Amy E Keating | |
| Sanjib Dutta | |||
| T Scott Chen | |||
| P2860 | cites work | Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function | Q24293924 |
| Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins | Q24302494 | ||
| Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members | Q24337108 | ||
| Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy | Q24635408 | ||
| The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity | Q24683846 | ||
| The structure of a Bcl-xL/Bim fragment complex: implications for Bim function | Q27642185 | ||
| Structural plasticity underpins promiscuous binding of the prosurvival protein A1 | Q27650558 | ||
| Completing the family portrait of the anti-apoptotic Bcl-2 proteins: crystal structure of human Bfl-1 in complex with Bim | Q27652276 | ||
| High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL | Q27653863 | ||
| Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes | Q27658925 | ||
| Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL | Q27660407 | ||
| Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX | Q27665695 | ||
| Dali server: conservation mapping in 3D | Q27860994 | ||
| Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2 | Q28261132 | ||
| An inhibitor of Bcl-2 family proteins induces regression of solid tumours | Q29547595 | ||
| The landscape of somatic copy-number alteration across human cancers | Q29547648 | ||
| The penultimate rotamer library | Q29615941 | ||
| ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor | Q29616727 | ||
| Structure-based redesign of the binding specificity of anti-apoptotic Bcl-x(L). | Q30423652 | ||
| A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization | Q33210206 | ||
| Isolating and engineering human antibodies using yeast surface display | Q33280948 | ||
| Yeast surface display for protein engineering and characterization | Q33299124 | ||
| Genomic-wide analysis of lymphatic metastasis-associated genes in human hepatocellular carcinoma | Q33399464 | ||
| Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages | Q33770336 | ||
| BH3-Only proteins-essential initiators of apoptotic cell death | Q34117362 | ||
| Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. | Q34146431 | ||
| Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes. | Q35131224 | ||
| The Bcl-2 family: roles in cell survival and oncogenesis. | Q35591695 | ||
| Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia | Q36611156 | ||
| The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis | Q36691376 | ||
| Predictive Bcl-2 family binding models rooted in experiment or structure | Q36692693 | ||
| Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes | Q36799170 | ||
| Yeast surface display for screening combinatorial polypeptide libraries | Q36865126 | ||
| Residence time of receptor-ligand complexes and its effect on biological function | Q37138452 | ||
| BCL2A1: the underdog in the BCL2 family | Q37954995 | ||
| Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1. | Q39646171 | ||
| Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist | Q40088689 | ||
| Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands. | Q40490346 | ||
| MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family | Q41839159 | ||
| The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling | Q41893473 | ||
| In silico and in vitro elucidation of BH3 binding specificity toward Bcl-2 | Q41958792 | ||
| Prediction of metastatic relapse in node-positive breast cancer: establishment of a clinicogenomic model after FEC100 adjuvant regimen | Q43958006 | ||
| Enhancing scatterplots with smoothed densities. | Q48553948 | ||
| Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: use of nonlinear least squares analysis methods. | Q52392958 | ||
| Characterization of peptide aptamers targeting Bfl-1 anti-apoptotic protein. | Q52610962 | ||
| General method for plasmid construction using homologous recombination | Q77812571 | ||
| Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax | Q77870361 | ||
| Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins | Q83215997 | ||
| P433 | issue | 4 | |
| P921 | main subject | computational biology | Q177005 |
| P304 | page(s) | 778-788 | |
| P577 | publication date | 2013-02-21 | |
| P1433 | published in | ACS Chemical Biology | Q165583 |
| P1476 | title | Peptide ligands for pro-survival protein Bfl-1 from computationally guided library screening | |
| P478 | volume | 8 |
| Q27684407 | A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells |
| Q47348359 | Binding modes of Bcl-2 homology 3 (BH3) peptides with anti-apoptotic protein A1 and redesign of peptide inhibitors: a computational study. |
| Q37452081 | Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer |
| Q36998291 | Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines |
| Q36290587 | Enriching Peptide Libraries for Binding Affinity and Specificity Through Computationally Directed Library Design. |
| Q33779035 | Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 |
| Q21145296 | Genome-wide prediction and validation of peptides that bind human prosurvival Bcl-2 proteins |
| Q35640928 | Locating Herpesvirus Bcl-2 Homologs in the Specificity Landscape of Anti-Apoptotic Bcl-2 Proteins. |
| Q31123704 | Molecular Determinants of Mutant Phenotypes, Inferred from Saturation Mutagenesis Data |
| Q90003530 | Multi-input chemical control of protein dimerization for programming graded cellular responses |
| Q57465813 | Peptide design by optimization on a data-parameterized protein interaction landscape |
| Q35170975 | Potent and specific peptide inhibitors of human pro-survival protein Bcl-xL. |
| Q99603835 | Selective Affimers Recognize the BCL-2 Family Proteins BCL-xL and MCL-1 through Non-Canonical Structural Motifs |
| Q27679468 | Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins |
| Q35171535 | SwiftLib: rapid degenerate-codon-library optimization through dynamic programming |
| Q91656339 | Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1 |
| Q30368405 | The functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains. |
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