Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3

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Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3 is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...854877S
P356DOI10.1371/JOURNAL.PONE.0054877
P932PMC publication ID3556037
P698PubMed publication ID23372785
P5875ResearchGate publication ID235393459

P50authorAndrew M RileyQ55240941
Barry PotterQ56559893
Colin W TaylorQ61472896
P2093author name stringStephen C Tovey
Taufiq Rahman
Huma Saleem
P2860cites workMolProbity: all-atom contacts and structure validation for proteins and nucleic acidsQ24684673
Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligandQ27639992
Apo and InsP3-bound crystal structures of the ligand-binding domain of an InsP3 receptorQ27673043
Structural and functional conservation of key domains in InsP3 and ryanodine receptorsQ27676937
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreadingQ27860652
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
Back in the water: the return of the inositol phosphatesQ28186774
IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptorQ28202808
Selective recognition of inositol phosphates by subtypes of the inositol trisphosphate receptorQ28360600
Regulation of inositol 1,4,5-trisphosphate receptors by cAMP independent of cAMP-dependent protein kinaseQ28508148
Differential distribution, clustering, and lateral diffusion of subtypes of the inositol 1,4,5-trisphosphate receptorQ28576028
Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptorsQ28592356
Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44Q28594382
Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel openingQ28594466
Comparative protein structure modeling using ModellerQ29615142
Flexible architecture of IP3R1 by Cryo-EMQ30503400
Small molecule-based laser inactivation of inositol 1,4,5-trisphosphate receptorQ30653049
Expression of inositol trisphosphate receptors.Q33834374
Inositol trisphosphate receptor Ca2+ release channels.Q33983069
Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor.Q34386939
IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.Q34455522
Subcellular distribution of the inositol 1,4,5-trisphosphate receptors: functional relevance and molecular determinantsQ35749144
Inositol 1,4,5-trisphosphate receptors as signal integratorsQ35799975
Location of the permeation pathway in the recombinant type 1 inositol 1,4,5-trisphosphate receptorQ36438961
Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.Q36788552
IP(3) receptors: toward understanding their activation.Q37803478
Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A.Q39411638
Clustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2+.Q39863840
Rapid functional assays of intracellular Ca2+ channels.Q40150139
Synthetic partial agonists reveal key steps in IP3 receptor activationQ40523623
Differential regulation of types-1 and -3 inositol trisphosphate receptors by cytosolic Ca2+Q41067966
Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptorQ41105707
Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors.Q41149797
Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gatingQ42067925
Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors.Q42159863
Second messenger specificity of the inositol trisphosphate receptor: reappraisal based on novel inositol phosphatesQ42603677
Activation of IP(3) receptors by synthetic bisphosphate ligandsQ42737227
Inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate formation in Ca2+-mobilizing-hormone-activated cellsQ42867000
Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by ins(1,3,4, 5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptorQ42990552
Hydrophobic modifications at 1-phosphate of inositol 1,4,5-trisphosphate analogues enhance receptor bindingQ43962778
Critical regions for activation gating of the inositol 1,4,5-trisphosphate receptorQ44350680
Interaction of the catalytic domain of inositol 1,4,5-trisphosphate 3-kinase A with inositol phosphate analoguesQ46583505
Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity.Q48568230
Molecular interactions of endogenous D-myo-inositol phosphates with the intracellular D-myo-inositol 1,4,5-trisphosphate recognition site.Q52511978
Amidines bearing benzofuroxan or benzimidazole 1,3-dioxide core scaffolds as Trypanosoma cruzi-inhibitors: structural basis for their interactions with cruzipainQ57268127
Effect of inositol 1,3,4,5-tetrakisphosphate on inositol trisphosphate-activated Ca2+ signaling in mouse lacrimal acinar cellsQ71091522
Immunohistochemical study of inositol 1,4,5-trisphosphate receptor type 3 in rat central nervous systemQ72252338
Differential expression of type 2 and type 3 inositol 1,4,5-trisphosphate receptor mRNAs in various mouse tissues: in situ hybridization studyQ72312534
Defining the minimal structural requirements for partial agonism at the type I myo-inositol 1,4,5-trisphosphate receptorQ73082603
Synthesis of D- and L-myo-Inositol 1,4,6-Trisphosphate, Regioisomers of a Ubiquitous Second MessengerQ74825032
New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptorQ77671814
Synthesis and evaluation of 1-position-modified inositol 1,4,5-trisphosphate analogsQ77974069
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)e54877
P577publication date2013-01-25
P1433published inPLOS OneQ564954
P1476titleStimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3
P478volume8

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cites work (P2860)
Q64933186A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.
Q30582040Focal activation of cells by plasmon resonance assisted optical injection of signaling molecules
Q39015655Interactions of antagonists with subtypes of inositol 1,4,5-trisphosphate (IP3) receptor.
Q34612793Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues
Q39217676Subtype-selective regulation of IP(3) receptors by thimerosal via cysteine residues within the IP(3)-binding core and suppressor domain
Q39474332Synthesis of dimeric analogs of adenophostin A that potently evoke Ca2+ release through IP3 receptors
Q48511134Synthesis of inositol phosphate-based competitive antagonists of inositol 1,4,5-trisphosphate receptors
Q37502964The "Other" Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo-Inositol Chemistry).
Q35600537Triazolophostins: a library of novel and potent agonists of IP3 receptors
Q89691493d-chiro-Inositol Ribophostin: A Highly Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities

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