review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0165-6147(98)01260-7 |
P698 | PubMed publication ID | 9850611 |
P2093 | author name string | R A Challiss | |
S R Nahorski | |||
R A Wilcox | |||
W U Primrose | |||
P2860 | cites work | Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells | Q27867708 |
Inositol trisphosphate and calcium signalling | Q28262867 | ||
Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor | Q28586214 | ||
Inhibition of nuclear vesicle fusion by antibodies that block activation of inositol 1,4,5-trisphosphate receptors | Q33912926 | ||
Activation of the calcium release channel (ryanodine receptor) by heparin and other polyanions is calcium dependent. | Q34436186 | ||
Catalytic properties of inositol trisphosphate kinase: activation by Ca2+ and calmodulin | Q34552219 | ||
Kinetics of smooth and skeletal muscle activation by laser pulse photolysis of caged inositol 1,4,5-trisphosphate | Q36460397 | ||
Quantal puffs of intracellular Ca2+ evoked by inositol trisphosphate in Xenopus oocytes | Q36702655 | ||
Plasma membrane inositol 1,4,5-trisphosphate receptor of lymphocytes: selective enrichment in sialic acid and unique binding specificity | Q36924230 | ||
Molecular recognition of inositol polyphosphates by intracellular receptors and metabolic enzymes | Q38281029 | ||
Intracellular channels | Q40392897 | ||
Inositol 1,4,5-trisphosphate receptor subtypes differentially recognize regioisomers of D-myo-inositol 1,4,5-trisphosphate | Q40873367 | ||
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression | Q41044051 | ||
Differential regulation of types-1 and -3 inositol trisphosphate receptors by cytosolic Ca2+ | Q41067966 | ||
The inositol triphosphate receptor family | Q41087607 | ||
Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor | Q41105707 | ||
Stable overexpression of the type-1 inositol 1,4,5-trisphosphate receptor in L fibroblasts: subcellular distribution and functional consequences | Q41167472 | ||
Type-I, Type-II and Type-III Inositol 1,4,5-Trisphosphate Receptor Co-Immunoprecipitation as Evidence for the Existence of Heterotetrameric Receptor Complexes | Q41313286 | ||
Heterotetrameric complex formation of inositol 1,4,5-trisphosphate receptor subunits | Q41334433 | ||
Type I, II, and III inositol 1,4,5-trisphosphate receptors are unequally susceptible to down-regulation and are expressed in markedly different proportions in different cell types | Q41345900 | ||
The InsP3 receptor and intracellular Ca2+ signaling | Q41541429 | ||
Interactions between inositol tris- and tetrakis-phosphates. Effects on intracellular Ca2+ mobilization in SH-SY5Y cells | Q41684296 | ||
Ca2+ differentially regulates the ligand-affinity states of type 1 and type 3 inositol 1,4,5-trisphosphate receptors | Q41856637 | ||
Inositol 1:2-cyclic,4,5-trisphosphate is only a weak agonist at inositol 1,4,5-trisphosphate receptors | Q41908498 | ||
Conformational changes in plant Ins(1,4,5)P3 receptor on interaction with different myo-inositol trisphosphates and its effect on Ca2+ release from microsomal fraction and liposomes | Q42123248 | ||
Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors. | Q42159863 | ||
Involvement of the C-terminus of the inositol 1,4,5-trisphosphate receptor in Ca2+ release analysed using region-specific monoclonal antibodies | Q42161881 | ||
Evidence for lithium-sensitive inositol 4,5-bisphosphate accumulation in muscarinic cholinoceptor-stimulated cerebral-cortex slices | Q42175853 | ||
Characterization of the inositol 1,4,5-trisphosphate-induced calcium release from permeabilized endocrine cells and its inhibition by decavanadate and p-hydroxymercuribenzoate | Q42802129 | ||
Inositol 1,4,5-trisphosphorothioate, a stable analogue of inositol trisphosphate which mobilizes intracellular calcium. | Q42836088 | ||
Single-channel kinetics, inactivation, and spatial distribution of inositol trisphosphate (IP3) receptors in Xenopus oocyte nucleus. | Q42977389 | ||
Ins(1,3,4,5)P4 is effective in mobilizing Ca2+ in mouse exocrine pancreatic acinar cells if phospholipase A2 is inhibited | Q42984416 | ||
Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor | Q46074332 | ||
The novel Ins(1,4,5)P3 analogue 3-amino-3-deoxy-Ins(1,4,5)P3: a pH-dependent Ins(1,4,5)P3 receptor partial agonist in SH-SY5Y neuroblastoma cells | Q48155829 | ||
Disaccharide polyphosphates based upon adenophostin A activate hepatic D-myo-inositol 1,4,5-trisphosphate receptors | Q48568062 | ||
2APB, 2-aminoethoxydiphenyl borate, a membrane-penetrable modulator of Ins(1,4,5)P3-induced Ca2+ release | Q48605432 | ||
Structural analogues of D-myo-inositol-1,4,5-trisphosphate and adenophostin A: recognition by cerebellar and platelet inositol-1,4,5-trisphosphate receptors | Q48619300 | ||
D-[35S(U)]inositol 1,4,5-trisphosphorothioate, a novel radioligand for the inositol 1,4,5-trisphosphate receptor. Complex binding to rat cerebellar membranes | Q48740561 | ||
The effects of inositol 1,4,5-trisphosphate (InsP3) analogues on the transient kinetics of Ca2+ release from cerebellar microsomes. InsP3 analogues act as partial agonists | Q48830363 | ||
Inositol 1,4,5-trisphosphate affinity chromatography | Q49020059 | ||
Role of inositol 1,4,5-trisphosphate receptor in ventral signaling in Xenopus embryos. | Q52191620 | ||
Modification at C2 of myo-inositol 1,4,5-trisphosphate produces inositol trisphosphates and tetrakisphosphates with potent biological activities. | Q54199952 | ||
3-position modification of myo-inositol 1,4,5-trisphosphate: consequences for intracellular Ca2+ mobilisation and enzyme recognition. | Q54267874 | ||
Structure and Function of Inositol 1,4,5-Trisphosphate Receptor | Q56482244 | ||
Binding and activity of the nine possible regioisomers of myo-inositol tetrakisphosphate at the inositol 1,4,5-trisphosphate receptor. | Q64956913 | ||
Interaction of synthetic D-6-deoxy-myo-inositol 1,4,5-trisphosphate with the Ca2(+)-releasing D-myo-inositol 1,4,5-trisphosphate receptor, and the metabolic enzymes 5-phosphatase and 3-kinase | Q67912703 | ||
Heparin inhibits inositol trisphosphate-induced calcium release from permeabilized rat liver cells | Q69815830 | ||
Synthesis of methyl 2-O-allyl-(and 3-O-allyl)-5-O-benzyl-beta-D- ribofuranoside | Q70983278 | ||
Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation | Q71084759 | ||
A Ca(2+)-mobilising carbohydrate-based polyphosphate: synthesis of 2-hydroxyethyl alpha-D-glucopyranoside 2',3,4-trisphosphate | Q71424690 | ||
Adenophostin-medicated quantal Ca2+ release in the purified and reconstituted inositol 1,4,5-trisphosphate receptor type 1 | Q71940805 | ||
Inositol 1,4,5-trisphosphate receptors: labeling the inositol 1,4,5-trisphosphate binding site with photoaffinity ligands | Q72951660 | ||
Defining the minimal structural requirements for partial agonism at the type I myo-inositol 1,4,5-trisphosphate receptor | Q73082603 | ||
Structure and function of inositol 1,4,5-trisphosphate receptor | Q73311223 | ||
Molecular and functional evidence for multiple Ca2+-binding domains in the type 1 inositol 1,4,5-trisphosphate receptor | Q73770572 | ||
Differences among type I, II, and III inositol-1,4,5-trisphosphate receptors in ligand-binding affinity influence the sensitivity of calcium stores to inositol-1,4,5-trisphosphate | Q74454404 | ||
P433 | issue | 11 | |
P921 | main subject | pharmacology | Q128406 |
P304 | page(s) | 467-475 | |
P577 | publication date | 1998-11-01 | |
P1433 | published in | Trends in Pharmacological Sciences | Q2451474 |
P1476 | title | New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor | |
P478 | volume | 19 |
Q83483032 | Adenophostins: High-Affinity Agonists of IP(3) Receptors |
Q31585475 | C-glycoside based mimics of D-myo-inositol 1,4,5-trisphosphate. |
Q36256801 | Cardiac expression of ryanodine receptor subtype 3; a strategic component in the intracellular Ca2+ release system of Purkinje fibers in large mammalian heart. |
Q34537344 | Defining the neuromolecular action of myo-inositol: application to obsessive-compulsive disorder |
Q58798779 | Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store release pathway |
Q43962778 | Hydrophobic modifications at 1-phosphate of inositol 1,4,5-trisphosphate analogues enhance receptor binding |
Q40873028 | Inhibition of Ca(2+) signalling by p130, a phospholipase-C-related catalytically inactive protein: critical role of the p130 pleckstrin homology domain |
Q31803134 | Inhibitory effects of ruthenium red on inositol 1,4, 5-trisphosphate-induced responses in rat megakaryocytes |
Q42012083 | Inhibitory mechanism of xestospongin-C on contraction and ion channels in the intestinal smooth muscle |
Q33279720 | Inositol-1,4,5-trisphosphate-mediated spontaneous activity in mouse embryonic stem cell-derived cardiomyocytes |
Q73115075 | Involvement of nitric oxide/cyclic GMP signaling pathway in the regulation of fatty acid metabolism in rat hepatocytes |
Q64986819 | Maintenance of homeostatic plasticity at the Drosophila neuromuscular synapse requires continuous IP3-directed signaling. |
Q21284458 | Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypeptides in human neutrophils |
Q28366084 | Mechanisms underlying reduced responsiveness of neonatal neutrophils to distinct chemoattractants |
Q33756111 | New Ca2+-releasing messengers: are they important in the nervous system? |
Q36364436 | Pharmacology of intracellular signalling pathways |
Q38547135 | Regulation of calcium clock-mediated pacemaking by inositol-1,4,5-trisphosphate receptors in mouse sinoatrial nodal cells. |
Q28360600 | Selective recognition of inositol phosphates by subtypes of the inositol trisphosphate receptor |
Q30653049 | Small molecule-based laser inactivation of inositol 1,4,5-trisphosphate receptor |
Q30956351 | Spatiotemporal laser inactivation of inositol 1,4,5-trisphosphate receptors using synthetic small-molecule probes |
Q34612793 | Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues |
Q34571414 | Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3 |
Q27639992 | Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand |
Q44066986 | Sympathoexcitation by bradykinin involves Ca2+-independent protein kinase C. |
Q44636378 | Synthesis and Ca2+-Mobilizing Activity of Purine-Modified Mimics of Adenophostin A: A Model for the Adenophostin−Ins(1,4,5)P3 Receptor Interaction |
Q44216590 | Synthesis of D- and L-myo-inositol 2,4,5-trisphosphate and trisphosphorothioate: structural analogues of D-myo-inositol 1,4,5-trisphosphate |
Q73221746 | The mycotoxin paxilline inhibits the cerebellar inositol 1,4, 5-trisphosphate receptor |
Q34089878 | Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution |
Q43264712 | Xestospongin C, a selective and membrane-permeable inhibitor of IP(3) receptor, attenuates the positive inotropic effect of alpha-adrenergic stimulation in guinea-pig papillary muscle |
Q43637492 | Xylopyranoside-based agonists of D-myo-inositol 1,4,5-trisphosphate receptors: synthesis and effect of stereochemistry on biological activity |
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