Human chorionic gonadotropin β induces migration and invasion via activating ERK1/2 and MMP-2 in human prostate cancer DU145 cells

scientific article

Human chorionic gonadotropin β induces migration and invasion via activating ERK1/2 and MMP-2 in human prostate cancer DU145 cells is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...854592L
P356DOI10.1371/JOURNAL.PONE.0054592
P932PMC publication ID3570544
P698PubMed publication ID23424616
P5875ResearchGate publication ID235670862

P2093author name stringYan Zhou
Wei Wu
Zongwen Li
Chunliu Li
Lianlian Du
P2860cites workExtracellular signal-regulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropinQ44970405
Platelet-derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP-2 production.Q46186672
Mifepristone attenuates human chorionic gonadotropin-induced extracellular signal-regulated kinase 1/2 phosphorylation, cyclooxygenase-2, and prostaglandin E2 production in human granulosa luteal cellsQ46986104
1alpha,25-dihydroxyvitamin D3 inhibits prostate cancer cell invasion via modulation of selective proteases.Q51417474
Does hCG or hCGβ play a role in cancer cell biology?Q51903561
MMP-9 overexpression due to TIMP-1 and RECK underexpression is associated with prognosis in prostate cancer.Q53278027
Human chorionic gonadotropin stimulates matrix metalloproteinases-2 and -9 in cytotrophoblastic cells and decreases tissue inhibitor of metalloproteinases-1, -2, and -3 in decidualized endometrial stromal cells.Q54545507
Importance of the detection method for intact dimeric human chorionic gonadotropin without interference with the free human chorionic gonadotropin beta subunit for pregnancy exclusion before liver transplantation in a woman with cholangiocarcinomaQ81336864
Enzyme Immunoassay of Urinary β-Core Fragment of Human Chorionic Gonadotropin as a Tumor Marker for Ovarian CancerQ83460170
Arsenic trioxide enhances the radiation sensitivity of androgen-dependent and -independent human prostate cancer cellsQ34171130
Human chorionic gonadotropin stimulates trophoblast invasion through extracellularly regulated kinase and AKT signalingQ34280674
Lycopene for the prevention and treatment of benign prostatic hyperplasia and prostate cancer: a systematic reviewQ34283034
Human chorionic gonadotrophin beta expression in malignant Barrett's oesophagusQ34340963
HCG variants, the growth factors which drive human malignancies.Q35609430
Endosulfan upregulates AP-1 binding and ARE-mediated transcription via ERK1/2 and p38 activation in HepG2 cellsQ35673434
Ethanol extracts of fruiting bodies of Antrodia cinnamomea suppress CL1-5 human lung adenocarcinoma cells migration by inhibiting matrix metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt signaling pathwaysQ35792849
Current Challenges in Prostate Cancer Management and the Rationale behind Targeted Focal TherapyQ35977609
Management of biochemical recurrence after primary localized therapy for prostate cancerQ35981941
New drug development in metastatic prostate cancerQ37204455
Human choriogonadotrophin protein core and sugar branches heterogeneity: basic and clinical insightsQ37306251
Human chorionic gonadotropin and associated moleculesQ37355881
Active surveillance versus surgery for low risk prostate cancer: a clinical decision analysis.Q37634841
Satisfaction with nurse-led telephone follow up for low to intermediate risk prostate cancer patients treated with radical radiotherapy. A comparative studyQ38011474
The cancer/testis antigen CAGE induces MMP-2 through the activation of NF-kappaB and AP-1.Q38348551
Bradykinin enhances cell migration in human prostate cancer cells through B2 receptor/PKCδ/c-Src dependent signaling pathwayQ39338856
Inhibitory effect of antibodies against human chorionic gonadotropin on the growth of colorectal tumour cellsQ39339286
Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathwaysQ39379601
The novel vitamin D analog ZK191784 inhibits prostate cancer cell invasion.Q39422250
Overexpression of MMP-9 contributes to invasiveness of prostate cancer cell line LNCaP.Q39578174
Evaluation of the immunogenicity of a single chain chimeric peptide composed of hCGβ and oLHα for inhibition of the growth of hCGβ-expressing cancer cellsQ39661016
Acacetin inhibits TPA-induced MMP-2 and u-PA expressions of human lung cancer cells through inactivating JNK signaling pathway and reducing binding activities of NF-kappaB and AP-1.Q39701554
CXCL12/CXCR4 promotes laryngeal and hypopharyngeal squamous cell carcinoma metastasis through MMP-13-dependent invasion via the ERK1/2/AP-1 pathwayQ39980986
Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signalingQ40151235
Human chorionic gonadotropin beta (HCGbeta) down-regulates E-cadherin and promotes human prostate carcinoma cell migration and invasionQ40344731
Cholecalciferol (vitamin D3) inhibits growth and invasion by up-regulating nuclear receptors and 25-hydroxylase (CYP27A1) in human prostate cancer cellsQ40374373
Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metalloproteinase CascadesQ41808886
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectprostate cancerQ181257
P304page(s)e54592
P577publication date2013-02-12
P1433published inPLOS OneQ564954
P1476titleHuman chorionic gonadotropin β induces migration and invasion via activating ERK1/2 and MMP-2 in human prostate cancer DU145 cells
P478volume8

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cites work (P2860)
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Q52629300miR-143-3p regulates cell proliferation and apoptosis by targeting IGF1R and IGFBP5 and regulating the Ras/p38 MAPK signaling pathway in rheumatoid arthritis.
Q61813537β-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway

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