scholarly article | Q13442814 |
P2093 | author name string | Michael E Pichichero | |
Ravinder Kaur | |||
Naveen Surendran | |||
Martina Ochs | |||
P2860 | cites work | Randomized controlled study of the safety and immunogenicity of pneumococcal vaccine formulations containing PhtD and detoxified pneumolysin with alum or adjuvant system AS02V in elderly adults | Q33601853 |
Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae | Q33739670 | ||
The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin | Q33996189 | ||
The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia | Q34002787 | ||
Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis | Q34005995 | ||
Differential protein expression in phenotypic variants of Streptococcus pneumoniae | Q34007754 | ||
Serotype replacement in disease after pneumococcal vaccination | Q34178363 | ||
Mn2+-dependent regulation of multiple genes in Streptococcus pneumoniae through PsaR and the resultant impact on virulence | Q34334220 | ||
Density and duration of pneumococcal carriage is maintained by transforming growth factor β1 and T regulatory cells | Q34479487 | ||
Preclinical Evaluation of the Pht Proteins as Potential Cross-Protective Pneumococcal Vaccine Antigens | Q34484575 | ||
Pneumolysin in pneumococcal adherence and colonization | Q34488348 | ||
Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae | Q34549615 | ||
Inhibition of pneumococcal adherence to human nasopharyngeal epithelial cells by anti-PsaA antibodies | Q34779050 | ||
Pneumolysin: a double-edged sword during the host-pathogen interaction | Q34824489 | ||
Nasopharyngeal antibodies to pneumococcal pneumolysin in children with acute otitis media | Q35225029 | ||
Uptake of Streptococcus pneumoniae by respiratory epithelial cells | Q35518668 | ||
Co-colonization by Haemophilus influenzae with Streptococcus pneumoniae enhances pneumococcal-specific antibody response in young children | Q35531214 | ||
Sequence heterogeneity of PsaA, a 37-kilodalton putative adhesin essential for virulence of Streptococcus pneumoniae | Q35532255 | ||
Streptococcus pneumoniae colonisation: the key to pneumococcal disease | Q35681330 | ||
Pneumolysin, PspA, and PspC contribute to pneumococcal evasion of early innate immune responses during bacteremia in mice | Q35783747 | ||
Serum antibody response to five Streptococcus pneumoniae proteins during acute otitis media in otitis-prone and non-otitis-prone children | Q35811715 | ||
Neutralizing antibodies elicited by a novel detoxified pneumolysin derivative, PlyD1, provide protection against both pneumococcal infection and lung injury | Q36018158 | ||
Vaccine candidates PhtD and PhtE of Streptococcus pneumoniae are adhesins that elicit functional antibodies in humans | Q36376010 | ||
Streptococcus pneumoniae protein vaccine candidates: properties, activities and animal studies | Q36558990 | ||
Antibody response to Streptococcus pneumoniae proteins PhtD, LytB, PcpA, PhtE and Ply after nasopharyngeal colonization and acute otitis media in children | Q36920037 | ||
Inhibition of human polymorphonuclear leukocyte respiratory burst, bactericidal activity, and migration by pneumolysin | Q37105935 | ||
The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease | Q37109940 | ||
Novel role for the Streptococcus pneumoniae toxin pneumolysin in the assembly of biofilms | Q37174555 | ||
Antibodies to pneumococcal proteins PhtD, CbpA, and LytC in Filipino pregnant women and their infants in relation to pneumococcal carriage | Q37213916 | ||
Surface association of Pht proteins of Streptococcus pneumoniae. | Q37264619 | ||
Pneumococcal surface adhesin A (PsaA): a review | Q37279975 | ||
A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae | Q37333825 | ||
Maternal antibodies to pneumolysin but not to pneumococcal surface protein A delay early pneumococcal carriage in high-risk Papua New Guinean infants | Q37410062 | ||
Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors | Q37459576 | ||
Role of Pht proteins in attachment of Streptococcus pneumoniae to respiratory epithelial cells | Q37713234 | ||
Safety and immunogenicity of a pneumococcal histidine triad protein D vaccine candidate in adults | Q38058158 | ||
Current status and perspectives on protein-based pneumococcal vaccines | Q38124921 | ||
Streptococcus pneumoniae surface protein PcpA elicits protection against lung infection and fatal sepsis | Q39023214 | ||
PcpA of Streptococcus pneumoniae mediates adherence to nasopharyngeal and lung epithelial cells and elicits functional antibodies in humans | Q39314657 | ||
Relationship between phase variation in colony morphology, intrastrain variation in cell wall physiology, and nasopharyngeal colonization by Streptococcus pneumoniae. | Q39825198 | ||
Molecular analysis of the pathogenicity of Streptococcus pneumoniae: the role of pneumococcal proteins | Q40619089 | ||
Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae | Q41080026 | ||
Export requirements of pneumolysin in Streptococcus pneumoniae. | Q42182834 | ||
Molecular characterization of PcpA: a novel choline-binding protein of Streptococcus pneumoniae | Q42681508 | ||
Structure-guided antigen engineering yields pneumolysin mutants suitable for vaccination against pneumococcal disease | Q42708867 | ||
Early predictors of mortality in pneumococcal bacteraemia | Q43801991 | ||
Pneumococcal histidine triad proteins are regulated by the Zn2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H. | Q46275942 | ||
Biochemical Characterization of the Histidine Triad Protein PhtD as a Cell Surface Zinc-Binding Protein of Pneumococcus | Q57242796 | ||
Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein | Q67816410 | ||
Pneumolysin induces the salient histologic features of pneumococcal infection in the rat lung in vivo | Q67903731 | ||
Association of intrastrain phase variation in quantity of capsular polysaccharide and teichoic acid with the virulence of Streptococcus pneumoniae | Q74184782 | ||
Otitis media | Q86354303 | ||
Vaccination with a Streptococcus pneumoniae trivalent recombinant PcpA, PhtD and PlyD1 protein vaccine candidate protects against lethal pneumonia in an infant murine model | Q87680192 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | antibody | Q79460 |
Streptococcus pneumoniae | Q221179 | ||
P304 | page(s) | 5069-5075 | |
P577 | publication date | 2014-09-22 | |
P1433 | published in | Infection and Immunity | Q6029193 |
P1476 | title | Human antibodies to PhtD, PcpA, and Ply reduce adherence to human lung epithelial cells and murine nasopharyngeal colonization by Streptococcus pneumoniae | |
P478 | volume | 82 |
Q37473239 | A bivalent pneumococcal histidine triad protein D-choline-binding protein A vaccine elicits functional antibodies that passively protect mice from Streptococcus pneumoniae challenge |
Q47602559 | Beyond binding: antibody effector functions in infectious diseases. |
Q90461757 | Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection |
Q47658958 | Development of pneumococcal vaccines over the last 10 years |
Q38378380 | Efficacy of a novel, protein-based pneumococcal vaccine against nasopharyngeal carriage of Streptococcus pneumoniae in infants: A phase 2, randomized, controlled, observer-blind study. |
Q90820622 | Efficacy, safety and immunogenicity of a pneumococcal protein-based vaccine co-administered with 13-valent pneumococcal conjugate vaccine against acute otitis media in young children: A phase IIb randomized study |
Q40254569 | Epigallocatechin gallate inhibits Streptococcus pneumoniae virulence by simultaneously targeting pneumolysin and sortase A. |
Q38795815 | Immunization with LytB protein of Streptococcus pneumoniae activates complement-mediated phagocytosis and induces protection against pneumonia and sepsis |
Q52365761 | Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1. |
Q35624139 | In vitro biofilm development of Streptococcus pneumoniae and formation of choline-binding protein-DNA complexes |
Q37625776 | Insights into structure and activity of natural compound inhibitors of pneumolysin |
Q40234319 | Juglone alleviates pneumolysin-induced human alveolar epithelial cell injury via inhibiting the hemolytic activity of pneumolysin |
Q53269550 | Liposomes as novel anti-infectives targeting bacterial virulence factors? |
Q37130191 | Next generation protein based Streptococcus pneumoniae vaccines |
Q64229705 | Novel Protein-Based Pneumococcal Vaccines: Assessing the Use of Distinct Protein Fragments Instead of Full-Length Proteins as Vaccine Antigens |
Q97883476 | Pneumolysin: Pathogenesis and Therapeutic Target |
Q90284439 | Prevalence of Various Vaccine Candidate Proteins in Clinical Isolates of Streptococcus pneumoniae: Characterization of the Novel Pht Fusion Proteins PhtA/B and PhtA/D |
Q37309218 | Rationale and prospects for novel pneumococcal vaccines |
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