Etoricoxib: a review of its use in the symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and acute gouty arthritis

scientific article

Etoricoxib: a review of its use in the symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and acute gouty arthritis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1028201157
P356DOI10.2165/00003495-200969110-00008
P698PubMed publication ID19634927

P2093author name stringM Asif A Siddiqui
Katherine F Croom
P2860cites workDo selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trialsQ24546221
New horizons and perspectives in the treatment of osteoarthritisQ24657795
EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)Q24675150
A multinational randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis [ISRCTN25142273].Q24794291
Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489].Q25257426
Safety of etoricoxib, a specific cyclooxygenase-2 inhibitor, in asthmatic patients with aspirin-exacerbated respiratory diseaseQ28200044
Inhibitors of cyclooxygenases: mechanisms, selectivity and usesQ28217593
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparisonQ28218927
Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular riskQ28219220
Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.Q31842803
EULAR evidence based recommendations for the management of hand osteoarthritis: report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT).Q33260652
OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelinesQ33320085
Responder analysis for pain relief and numbers needed to treat in a meta-analysis of etoricoxib osteoarthritis trials: bridging a gap between clinical trials and clinical practiceQ33566361
A Comparison of Cardiovascular Biomarkers in Patients Treated for Three Months with Etoricoxib, Celecoxib, Ibuprofen, and PlaceboQ33633625
Randomised double blind trial of etoricoxib and indometacin in treatment of acute gouty arthritisQ33875514
A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirinQ33952053
Single- and multiple-dose pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, in man.Q34183755
Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitorQ34515171
Absorption, metabolism, and excretion of etoricoxib, a potent and selective cyclooxygenase-2 inhibitor, in healthy male volunteersQ34530443
Pharmacokinetics of etoricoxib in patients with renal impairmentQ34544012
The incidence of upper gastrointestinal adverse events in clinical trials of etoricoxib vs. non-selective NSAIDs: an updated combined analysisQ34558759
Efficacy and safety of etoricoxib 30 mg and celecoxib 200 mg in the treatment of osteoarthritis in two identically designed, randomized, placebo-controlled, non-inferiority studiesQ34570399
Gastrointestinal side effects of etoricoxib in patients with osteoarthritis: results of the Etoricoxib versus Diclofenac Sodium Gastrointestinal Tolerability and Effectiveness (EDGE) trial.Q34575707
Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparisonQ34582722
Risk of myocardial infarction associated with selective COX-2 inhibitors: meta-analysis of randomised controlled trials.Q34653947
Celecoxib inhibits 5-lipoxygenaseQ34656902
Clinical pharmacokinetic and pharmacodynamic profile of etoricoxibQ34847583
EtoricoxibQ35016968
Gout epidemiology: results from the UK General Practice Research Database, 1990-1999.Q35555160
ASAS/EULAR recommendations for the management of ankylosing spondylitisQ35637012
EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT).Q35638360
Renal effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs in controlled clinical trialsQ35680546
???Q28199855
Evaluation of the efficacy and safety of etoricoxib compared with naproxen in two, 138-week randomised studies of patients with osteoarthritisQ35954438
Systematic review and meta-analysis of the risk of major cardiovascular events with etoricoxib therapyQ36285978
The burden of musculoskeletal disease--a global perspectiveQ36446201
The burden of ankylosing spondylitis.Q36623885
Coxibs and heart disease: what we have learned and what else we need to knowQ36701215
Evidence-based recommendations for the management of ankylosing spondylitis: systematic literature search of the 3E Initiative in Rheumatology involving a broad panel of experts and practising rheumatologistsQ37085249
Cardiovascular safety and gastrointestinal tolerability of etoricoxib vs diclofenac in a randomized controlled clinical trial (The MEDAL study).Q41998132
In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663).Q43591309
Dose proportionality of oral etoricoxib, a highly selective cyclooxygenase-2 inhibitor, in healthy volunteersQ43754371
Efficacy and tolerability profile of etoricoxib in patients with osteoarthritis: A randomized, double-blind, placebo and active-comparator controlled 12-week efficacy trialQ43997545
A randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis.Q44103550
Results of a randomized, dose-ranging trial of etoricoxib in patients with osteoarthritis.Q44123837
Early response to COX-2 inhibitors as a predictor of overall response in osteoarthritis: pooled results from two identical trials comparing etoricoxib, celecoxib and placeboQ44162505
Complementary studies of the gastrointestinal safety of the cyclo-oxygenase-2-selective inhibitor etoricoxibQ44282395
Characterization of etoricoxib, a novel, selective COX-2 inhibitorQ44484802
The gastrointestinal safety of the COX-2 selective inhibitor etoricoxib assessed by both endoscopy and analysis of upper gastrointestinal eventsQ44542155
Pharmacokinetics of Etoricoxib in Patients with Hepatic ImpairmentQ44601145
A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritisQ44700625
Efficacy and safety profile of treatment with etoricoxib 120 mg once daily compared with indomethacin 50 mg three times daily in acute gout: a randomized controlled trialQ44762080
Economic evaluation of etoricoxib versus non-selective NSAIDs in the treatment of osteoarthritis and rheumatoid arthritis patients in the UK.Q44971339
The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.Q45040968
Use of gastroprotective agents and discontinuations due to dyspepsia with the selective cyclooxygenase-2 inhibitor etoricoxib compared with non-selective NSAIDsQ45257806
Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug diclofenac.Q45940021
Factors associated with blood pressure changes in patients receiving diclofenac or etoricoxib: results from the MEDAL study.Q45974086
The effect of etoricoxib on the pharmacokinetics of oral contraceptives in healthy participants.Q46011350
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL programQ46043878
Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxibQ46382423
Evaluation of the efficacy of etoricoxib in ankylosing spondylitis: results of a fifty-two-week, randomized, controlled studyQ46428507
Evaluation of the comparative efficacy of etoricoxib and ibuprofen for treatment of patients with osteoarthritis: A randomized, double-blind, placebo-controlled trialQ46428706
Effects of etoricoxib on the pharmacokinetics of phenytoin.Q46621565
Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjectsQ46628463
Effects of nonsteroidal anti-inflammatory drugs on the expression of urokinase plasminogen activator and inhibitor and gelatinases in the early osteoarthritic knee of humansQ46905036
Economic evaluation of etoricoxib versus non-selective NSAIDs in the treatment of ankylosing spondylitis in the UK.Q46923214
Gastrointestinal tolerability of etoricoxib in rheumatoid arthritis patients: results of the etoricoxib vs diclofenac sodium gastrointestinal tolerability and effectiveness trial (EDGE-II).Q46927526
British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of rheumatoid arthritis (after the first 2 years).Q51853711
A randomized placebo-controlled trial comparing the efficacy of etoricoxib 30 mg and ibuprofen 2400 mg for the treatment of patients with osteoarthritis.Q51910355
British Society for Rheumatology and british health professionals in Rheumatology guideline for the management of rheumatoid arthritis (the first two years).Q51937590
Lack of effect of antacids on single-dose pharmacokinetics of etoricoxibQ57221140
Pooled analysis of thrombotic cardiovascular events in clinical trials of the COX-2 selective Inhibitor etoricoxibQ79695252
The effect of etoricoxib on the pharmacodynamics and pharmacokinetics of warfarinQ80177912
Etoricoxib versus naproxen in patients with rheumatoid arthritis: a prospective, randomized, comparator-controlled 121-week trialQ80793608
Different COX-independent effects of the COX-2 inhibitors etoricoxib and lumiracoxibQ83107186
Association of baseline disease and patient characteristics with response to etoricoxib and indomethacin for acute goutQ94534823
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectosteoarthritisQ62736
rheumatoid arthritisQ187255
ankylosing spondylitisQ52849
P304page(s)1513-1532
P577publication date2009-07-01
P1433published inDrugsQ3040094
P1476titleEtoricoxib: a review of its use in the symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and acute gouty arthritis
P478volume69

Reverse relations

cites work (P2860)
Q53508065A distonic radical-ion for detection of traces of adventitious molecular oxygen (O2) in collision gases used in tandem mass spectrometers.
Q36163165A randomized, clinical trial to assess the relative efficacy and tolerability of two doses of etoricoxib versus naproxen in patients with ankylosing spondylitis
Q38993297Efficacy and tolerability of naproxen/esomeprazole magnesium tablets compared with non-specific NSAIDs and COX-2 inhibitors: a systematic review and network analyses
Q47756560Etoricoxib improves osteoarthritis pain relief, joint function, and quality of life in the extreme elderly
Q33880198Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
Q34556831Relative cardiovascular and gastrointestinal safety of non-selective non-steroidal anti-inflammatory drugs versus cyclo-oxygenase-2 inhibitors: implications for clinical practice
Q60678518Similar Maximum Systemic but not Local Cyclooxygenase-2 Inhibition by 50 mg Lumiracoxib and 90 mg Etoricoxib: A Randomized Controlled Trial in Healthy Subjects
Q53602109Status of etoricoxib in the treatment of rheumatic diseases. Expert panel opinion.

Search more.