Clinical pharmacokinetic and pharmacodynamic profile of etoricoxib

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Clinical pharmacokinetic and pharmacodynamic profile of etoricoxib is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1043963067
P356DOI10.2165/00003088-200847110-00002
P698PubMed publication ID18840026
P5875ResearchGate publication ID23304474

P2093author name stringNeal M Davies
Connie M Remsberg
Karina R Vega-Villa
Jody K Takemoto
Jonathan K Reynolds
P2860cites workA multinational randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis [ISRCTN25142273].Q24794291
Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489].Q25257426
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study GroupQ28138338
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COX-2 selective inhibitors cardiac toxicity: getting to the heart of the matterQ28211053
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trialQ28217835
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparisonQ28218927
Global gastrointestinal safety profile of etoricoxib and lumiracoxibQ28219335
Anti-inflammatory and analgesic actions of etoricoxib (an NSAID) combined with misoprostolQ28573702
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma preventionQ29620087
Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.Q31842803
High-throughput, semi-automated determination of a cyclooxygenase II inhibitor in human plasma and urine using solid-phase extraction in the 96-well format and high-performance liquid chromatography with post-column photochemical derivatization-fluoQ32114738
A liquid chromatography-mass spectrometry method for the quantification of both etoricoxib and valdecoxib in human plasmaQ33207757
Simultaneous quantitation of etoricoxib, salicylic acid, valdecoxib, ketoprofen, nimesulide and celecoxib in plasma by high-performance liquid chromatography with UV detectionQ33218819
Randomised double blind trial of etoricoxib and indometacin in treatment of acute gouty arthritisQ33875514
Clinical pharmacokinetics and pharmacodynamics of celecoxib: a selective cyclo-oxygenase-2 inhibitorQ33882627
Choosing the right nonsteroidal anti-inflammatory drug for the right patient: a pharmacokinetic approachQ33937522
Pharmacokinetics of rofecoxib: a specific cyclo-oxygenase-2 inhibitor.Q33966421
Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgeryQ33985078
The coxibs, selective inhibitors of cyclooxygenase-2.Q34086325
Single- and multiple-dose pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, in man.Q34183755
Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitorQ34515171
Absorption, metabolism, and excretion of etoricoxib, a potent and selective cyclooxygenase-2 inhibitor, in healthy male volunteersQ34530443
Pharmacokinetics of etoricoxib in patients with renal impairmentQ34544012
The incidence of upper gastrointestinal adverse events in clinical trials of etoricoxib vs. non-selective NSAIDs: an updated combined analysisQ34558759
Adverse effects of cyclooxygenase 2 inhibitors on renal and arrhythmia events: meta-analysis of randomized trialsQ34565640
Efficacy and safety of etoricoxib 30 mg and celecoxib 200 mg in the treatment of osteoarthritis in two identically designed, randomized, placebo-controlled, non-inferiority studiesQ34570399
Gastrointestinal side effects of etoricoxib in patients with osteoarthritis: results of the Etoricoxib versus Diclofenac Sodium Gastrointestinal Tolerability and Effectiveness (EDGE) trial.Q34575707
Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparisonQ34582722
Celecoxib inhibits 5-lipoxygenaseQ34656902
Pharmacokinetic/pharmacodynamic modelling of NSAIDs in a model of reversible inflammation in the catQ35545077
Renal effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs in controlled clinical trialsQ35680546
Cyclooxygenase-3: axiom, dogma, anomaly, enigma or splice error?--Not as easy as 1, 2, 3.Q35887563
Evaluation of the efficacy and safety of etoricoxib compared with naproxen in two, 138-week randomised studies of patients with osteoarthritisQ35954438
Pharmacokinetic-pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitorsQ36108232
Clinical pharmacology of lumiracoxib, a second-generation cyclooxygenase 2 selective inhibitorQ36120809
An overview of the recent developments in analytical methodologies for determination of COX-2 inhibitors in bulk drugs, pharmaceuticals and biological matricesQ36189859
Minimizing risks of NSAIDs: cardiovascular, gastrointestinal and renalQ36673018
Efficacy of the newest COX-2 selective inhibitors in rheumatic diseaseQ36907440
The analgesic effect of etoricoxib relative to that of cetaminophen analgesics: a randomized, controlled single-dose study in acute dental impaction painQ39367338
The analgesic efficacy of etoricoxib compared with oxycodone/acetaminophen in an acute postoperative pain model: a randomized, double-blind clinical trialQ39376666
Etoricoxib in acute pain associated with dental surgery: a randomized, double-blind, placebo- and active comparator-controlled dose-ranging studyQ39379167
A randomized, double-blind, parallel-group study comparing the analgesic effect of etoricoxib to placebo, naproxen sodium, and acetaminophen with codeine using the dental impaction pain modelQ39381510
Relationship between naproxen plasma concentration and its anti-inflammatory effect in experimental hepatitisQ40685829
Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: possible physiological and therapeutic implicationsQ41195345
Preparation and characterization of etoricoxib solid dispersions using lipid carriers by spray drying techniqueQ41990256
Simultaneous determination of unlabeled and carbon-13-labeled etoricoxib, a new cyclooxygenase-2 inhibitor, in human plasma using HPLC-MS/MS.Q42163336
In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663).Q43591309
Dose proportionality of oral etoricoxib, a highly selective cyclooxygenase-2 inhibitor, in healthy volunteersQ43754371
???Q28199855
Efficacy and tolerability profile of etoricoxib in patients with osteoarthritis: A randomized, double-blind, placebo and active-comparator controlled 12-week efficacy trialQ43997545
A randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis.Q44103550
Results of a randomized, dose-ranging trial of etoricoxib in patients with osteoarthritis.Q44123837
Determination of etoricoxib in human plasma by liquid chromatography–tandem mass spectrometry with electrospray ionisationQ44410333
Characterization of etoricoxib, a novel, selective COX-2 inhibitorQ44484802
Pharmacokinetics of Etoricoxib in Patients with Hepatic ImpairmentQ44601145
A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritisQ44700625
Efficacy and safety profile of treatment with etoricoxib 120 mg once daily compared with indomethacin 50 mg three times daily in acute gout: a randomized controlled trialQ44762080
The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.Q45040968
Isolation and structural characterization of the photolysis products of etoricoxib.Q45215294
Validated liquid chromatographic ultraviolet method for the quantitation of Etoricoxib in human plasma using liquid-liquid extractionQ45233715
Use of gastroprotective agents and discontinuations due to dyspepsia with the selective cyclooxygenase-2 inhibitor etoricoxib compared with non-selective NSAIDsQ45257806
In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactionsQ46347800
Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxibQ46382423
Evaluation of the comparative efficacy of etoricoxib and ibuprofen for treatment of patients with osteoarthritis: A randomized, double-blind, placebo-controlled trialQ46428706
Effects of etoricoxib on the pharmacokinetics of phenytoin.Q46621565
Analysis of interaction between etoricoxib and tramadol against mechanical hyperalgesia of spinal cord injury in ratsQ46719088
Validation of a capillary zone electrophoresis method for the comparative determination of etoricoxib in pharmaceutical formulationsQ46858041
Effects of nonsteroidal anti-inflammatory drugs on the expression of urokinase plasminogen activator and inhibitor and gelatinases in the early osteoarthritic knee of humansQ46905036
Gastrointestinal tolerability of etoricoxib in rheumatoid arthritis patients: results of the etoricoxib vs diclofenac sodium gastrointestinal tolerability and effectiveness trial (EDGE-II).Q46927526
Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium dietQ46958920
Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control studyQ48521294
A randomized placebo-controlled trial comparing the efficacy of etoricoxib 30 mg and ibuprofen 2400 mg for the treatment of patients with osteoarthritis.Q51910355
Lack of effect of antacids on single-dose pharmacokinetics of etoricoxibQ57221140
Pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of diclofenac in the ratQ73599156
Toxicokinetics of indomethacin-induced intestinal permeability in the ratQ73842574
Influence of dosage form on the gastroenteropathy of flurbiprofen in the rat: evidence of shift in the toxicity siteQ74061552
The pharmacology of selective inhibition of COX-2Q79144905
Validation of liquid chromatography and liquid chromatography/tandem mass spectrometry methods for the determination of etoricoxib in pharmaceutical formulationsQ79245300
In-line measurement of a drug substance via near infrared spectroscopy to ensure a robust crystallization processQ80177705
The effect of etoricoxib on the pharmacodynamics and pharmacokinetics of warfarinQ80177912
Different COX-independent effects of the COX-2 inhibitors etoricoxib and lumiracoxibQ83107186
P433issue11
P921main subjectpharmacokineticsQ323936
pharmacodynamicsQ725307
P304page(s)703-720
P577publication date2008-01-01
P1433published inClinical PharmacokineticsQ5133788
P1476titleClinical pharmacokinetic and pharmacodynamic profile of etoricoxib
P478volume47

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cites work (P2860)
Q24615651A turbulent decade for NSAIDs: update on current concepts of classification, epidemiology, comparative efficacy, and toxicity
Q38262502Comparative evaluation of cardiovascular outcomes in patients with osteoarthritis and rheumatoid arthritis on recommended doses of nonsteroidal anti-inflammatory drugs
Q64110949Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain
Q33934086Etoricoxib--preemptive and postoperative analgesia (EPPA) in patients with laparotomy or thoracotomy--design and protocols
Q41833844Etoricoxib-induced life-threatening hyperkalemia and acute kidney dysfunction against the background of telmisartan and a low sodium diet
Q34610283Etoricoxib: a review of its use in the symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and acute gouty arthritis
Q91791002Intra-articular injection of etoricoxib-loaded PLGA-PEG-PLGA triblock copolymeric nanoparticles attenuates osteoarthritis progression
Q48252693No effect of the cyclooxygenase-2 inhibitor etoricoxib on pre-emptive and post-operative analgesia in visceral surgery: results of a randomized controlled trial.
Q98830220Pharmacokinetic characterization of fluorocoxib D, a cyclooxygenase-2-targeted optical imaging agent for detection of cancer
Q59103166Postoperative Etoricoxib versus Ketoprofen Administration for Pain Management after Total Knee Arthroplasty: A Randomized, Double-Blind Controlled Study
Q36356814Single-dose safety and pharmacokinetic evaluation of fluorocoxib A: pilot study of novel cyclooxygenase-2-targeted optical imaging agent in a canine model
Q39243668The first example of a patient with etoricoxib-induced immune hemolytic anemia

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