Opioid receptor polymorphisms and opioid abuse

scientific article

Opioid receptor polymorphisms and opioid abuse is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1517/14622416.3.2.219
P698PubMed publication ID11972443

P2093author name stringAndrew P Smith
Nancy M Lee
P2860cites workSingle-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addictionQ24320057
G-protein-coupled receptor heterodimerization modulates receptor functionQ24603239
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitusQ28771769
Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytesQ31520490
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signalingQ31532158
The genetic mediation of individual differences in sensitivity to pain and its inhibitionQ33679576
The mu opiate receptor as a candidate gene for pain: polymorphisms, variations in expression, nociception, and opiate responsesQ33679584
Studies on mu and delta opioid receptor selectivity utilizing chimeric and site-mutagenized receptorsQ33679621
Mouse mu opioid receptor gene expression. A 34-base pair cis-acting element inhibits transcription of the mu opioid receptor gene from the distal promoterQ34401595
Genomic structure analysis of promoter sequence of a mouse mu opioid receptor geneQ35762035
Identification of a neurorestrictive suppressor element (NRSE) in the human mu-opioid receptor geneQ38298930
Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.Q40817051
Localization of promoter elements in the human mu-opioid receptor gene and regulation by DNA methylationQ40946137
A conserved arginine in the distal third intracellular loop of the mu-opioid receptor is required for G protein activationQ40970998
Identification of serine 356 and serine 363 as the amino acids involved in etorphine-induced down-regulation of the mu-opioid receptor.Q40988621
Dual promoters of mouse mu-opioid receptor geneQ41109711
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor geneQ41157124
Modulation of mu-mediated antinociception by delta agonists in the mouse: selective potentiation of morphine and normorphine by [D-Pen2,D-Pen5]enkephalinQ41271778
Pharmacology and regulation of the neuronal dopamine transporterQ41460319
Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by delta2-opioid receptorsQ42438400
Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin bindingQ42507483
Quantitative trait loci influencing morphine antinociception in four mapping populations.Q43649309
Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependenceQ43652684
Morphine tolerance in mice is independent of polymorphisms in opioid receptor sequences.Q43654298
Transcriptional regulation of the human mu opioid receptor (hMOR) gene: evidence of positive and negative cis-acting elements in the proximal promoter and presence of a distal promoterQ43708231
Morphine tolerance in spinal cord is due to interaction between mu- and delta-receptorsQ43830170
Role for the C-terminus in agonist-induced mu opioid receptor phosphorylation and desensitizationQ44331716
Oligomerization of mu- and delta-opioid receptors. Generation of novel functional propertiesQ44331872
Identification of the amino acid residues involved in selective agonist binding in the first extracellular loop of the δ‐ and μ‐opioid receptorsQ44333522
Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependenceQ44333907
Association between mu opioid receptor gene polymorphisms and Chinese heroin addictsQ44335420
Opioid delta-receptor involvement in supraspinal and spinal antinociception in miceQ44342101
Association between a delta opioid receptor gene polymorphism and heroin dependence in man.Q44346554
Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tailQ44346933
Population studies of polymorphisms at loci of neuropsychiatric interest (tryptophan hydroxylase (TPH), dopamine transporter protein (SLC6A3), D3 dopamine receptor (DRD3), apolipoprotein E (APOE), mu opioid receptor (OPRM1), and ciliary neurotrophicQ44350388
Opioid peptide receptor studies, 11: involvement of Tyr148, Trp318 and His319 of the rat mu-opioid receptor in binding of mu-selective ligandsQ44351724
Functional role of the spatial proximity of Asp114(2.50) in TMH 2 and Asn332(7.49) in TMH 7 of the mu opioid receptorQ44351857
ASP147 in the third transmembrane helix of the rat mu opioid receptor forms ion-pairing with morphine and naltrexoneQ44352419
Human delta-opioid receptor gene and susceptibility to heroin and alcohol dependenceQ44352797
Genetics of two mu opioid receptor gene (OPRM1) exon I polymorphisms: population studies, and allele frequencies in alcohol- and drug-dependent subjectsQ44352947
On the road to understanding addictionQ47862035
The potentiation of spinal analgesia by leucine enkephalin.Q51877813
Genetic and environmental influences on adolescent substance use and abuse.Q52072100
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectopioidQ427523
P304page(s)219-227
P577publication date2002-03-01
P1433published inPharmacogenomicsQ15724625
P1476titleOpioid receptor polymorphisms and opioid abuse
P478volume3

Reverse relations

cites work (P2860)
Q35581558Endogenous opiates and behavior: 2002
Q44703426Pain thresholds in alcohol preferring and non-preferring rats: diurnal and repeated trial line differences
Q34553463The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor.

Search more.