Proteomic analysis highlights the molecular complexities of native Kv4 channel macromolecular complexes

scientific article published on October 17, 2010

Proteomic analysis highlights the molecular complexities of native Kv4 channel macromolecular complexes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.SEMCDB.2010.10.004
P953full work available at URLhttps://europepmc.org/articles/pmc3046235?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20959143/?tool=EBI
https://europepmc.org/articles/PMC3046235
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20959143/pdf/?tool=EBI
https://europepmc.org/articles/PMC3046235?pdf=render
https://api.elsevier.com/content/article/PII:S1084952110001667?httpAccept=text/xml
https://doi.org/10.1016/j.semcdb.2010.10.004
https://api.elsevier.com/content/article/PII:S1084952110001667?httpAccept=text/plain
P932PMC publication ID3046235
P698PubMed publication ID20959143
P5875ResearchGate publication ID47499791

P2093author name stringCéline Marionneau
R. Reid Townsend
Jeanne M. Nerbonne
P2860cites workModulation of A-type potassium channels by a family of calcium sensorsQ22253194
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DPP10 modulates Kv4-mediated A-type potassium channelsQ24292726
EH domain proteins regulate cardiac membrane protein targetingQ24314283
Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interactionQ24322255
Alpha-actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca2+-activated K+ channel (SK2 channel)Q24322958
Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like propertiesQ24544159
Expression and function of dipeptidyl-aminopeptidase-like protein 6 as a putative beta-subunit of human cardiac transient outward current encoded by Kv4.3Q24544303
Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexesQ24550206
Cluster analysis of mass spectrometry data reveals a novel component of SAGAQ27937089
Large-scale analysis of the yeast proteome by multidimensional protein identification technologyQ28131778
A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channelsQ28182481
A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardiaQ28211696
The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptorsQ28277413
KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brainQ28281102
Kvbeta subunits increase expression of Kv4.3 channels by interacting with their C terminiQ40841064
Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunitQ41009542
The roles of molecular chaperones in vivo.Q41504485
Acquired dendritic channelopathy in temporal lobe epilepsyQ44992557
Protein complex analysis of native brain potassium channels by proteomics.Q46255034
Altered synaptic and non-synaptic properties of CA1 pyramidal neurons in Kv4.2 knockout miceQ46530219
Functional role of the fast transient outward K+ current IA in pyramidal neurons in (rat) primary visual cortex.Q46738283
Electrical remodelling maintains firing properties in cortical pyramidal neurons lacking KCND2-encoded A-type K+ currentsQ46813848
Funding for malaria genome sequencingQ48036880
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons.Q48361408
Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.Q48478462
K+ channel regulation of signal propagation in dendrites of hippocampal pyramidal neuronsQ48681398
Analysis of complex protein mixtures with improved sequence coverage using (CE-MS/MS)nQ79232668
Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunctionQ81492019
Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytesQ28504441
Proteomic analyses of native brain K(V)4.2 channel complexesQ28513349
The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1Q28567361
The CD26-related dipeptidyl aminopeptidase-like protein DPPX is a critical component of neuronal A-type K+ channelsQ28568564
Kv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neuronesQ28579059
AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channelsQ28592333
Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapsesQ28592888
Label-free detection of differential protein expression by LC/MALDI mass spectrometryQ33328270
Molecular determinants of cardiac transient outward potassium current (I(to)) expression and regulationQ33618573
Voltage-gated potassium channels: from hyperexcitability to excitementQ33665556
Molecular diversity of K+ channelsQ33691506
Multisite phosphorylation of voltage-gated sodium channel alpha subunits from rat brainQ33770959
Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunitsQ33821734
Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MSQ33883012
Dendritic ion channel trafficking and plasticity.Q33987823
Structure and function of Kv4-family transient potassium channelsQ34335214
Localization of voltage-gated ion channels in mammalian brainQ35672531
Presynaptic K+ channels: electrifying regulators of synaptic terminal excitability.Q35718153
Molecular physiology and modulation of somatodendritic A-type potassium channelsQ35958045
Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expressionQ36289048
Structure and function in dipeptidyl peptidase IV and related proteinsQ36478604
Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neuronsQ36956963
Profiling the phospho-status of the BKCa channel alpha subunit in rat brain reveals unexpected patterns and complexityQ36959240
Potassium channel phosphorylation in excitable cells: providing dynamic functional variability to a diverse family of ion channelsQ37082375
Rapid, bidirectional remodeling of synaptic NMDA receptor subunit composition by A-type K+ channel activity in hippocampal CA1 pyramidal neuronsQ37086625
Comparative LC-MS: a landscape of peaks and valleysQ37093728
The dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channelsQ37136584
Potassium channels: newly found players in synaptic plasticityQ37138885
Kv4.2 is a locus for PKC and ERK/MAPK cross-talkQ37212567
Weighing the evidence for a ternary protein complex mediating A-type K+ currents in neuronsQ37290754
New dimensions in the study of protein complexes using quantitative mass spectrometryQ37450054
Role of heteromultimers in the generation of myocardial transient outward K+ currents.Q38290963
Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes.Q39739639
Interaction of syntaxin 1A with the N-terminus of Kv4.2 modulates channel surface expression and gatingQ40088545
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.Q40242350
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmacromoleculeQ178593
P304page(s)145-152
P577publication date2010-10-17
P1433published inSeminars in Cell & Developmental BiologyQ14330411
P1476titleProteomic analysis highlights the molecular complexities of native Kv4 channel macromolecular complexes
P478volume22

Reverse relations

cites work (P2860)
Q92192925Applications for Mass Spectrometry in the Study of Ion Channel Structure and Function
Q30363845Applications for mass spectrometry in the study of ion channel structure and function.
Q26864362CaMKII regulation of cardiac K channels
Q40917448Crystallization and preliminary X-ray diffraction analysis of human dipeptidyl peptidase 10 (DPPY), a component of voltage-gated potassium channels
Q36021537Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels
Q28087459Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death
Q30457731Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing
Q27312770Kv4.2 and accessory dipeptidyl peptidase-like protein 10 (DPP10) subunit preferentially form a 4:2 (Kv4.2:DPP10) channel complex
Q36456672Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites.
Q37681403Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunits
Q38151974Potassium channels: structures, diseases, and modulators
Q34844871Repolarizing cardiac potassium channels: multiple sites and mechanisms for CaMKII-mediated regulation
Q28541685S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation
Q45146704Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents
Q35944812The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.
Q37968125The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome
Q42069269Voltage-gated ion channel accessory subunits: sodium, potassium, or both?

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