Stimulation of mast cells leads to cholesterol accumulation in macrophages in vitro by a mast cell granule-mediated uptake of low density lipoprotein

scientific article

Stimulation of mast cells leads to cholesterol accumulation in macrophages in vitro by a mast cell granule-mediated uptake of low density lipoprotein is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1987PNAS...84.2287K
P356DOI10.1073/PNAS.84.8.2287
P932PMC publication ID304635
P698PubMed publication ID3470793
P5875ResearchGate publication ID19685133

P2093author name stringKovanen PT
Kokkonen JO
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol depositionQ28625661
Insoluble low-density lipoprotein-proteoglycan complexes enhance cholesteryl ester accumulation in macrophagesQ35835281
Electron microscope observations on compounds 48-80-induced degranulation in rat mast cells. Evidence for sequential exocytosis of storage granulesQ36503120
Inhibition of lipoprotein binding to cell surface receptors of fibroblasts following selective modification of arginyl residues in arginine-rich and B apoproteinsQ40099596
The mast cellQ40103692
Basophils and mast cells: morphologic insights into their biology, secretory patterns, and functionQ40116600
Structure and function of the chemical mediators of mast cellsQ40140643
Degradation of low density lipoprotein . dextran sulfate complexes associated with deposition of cholesteryl esters in mouse macrophagesQ40238746
Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. Role of subplasmalemmal microfilamentsQ41182472
Uptake and degradation of mast-cell granules by mouse peritoneal macrophagesQ41902395
Complexes of low-density lipoproteins and arterial proteoglycan aggregates promote cholesteryl ester accumulation in mouse macrophagesQ41916327
The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.Q41926217
Low-density-lipoprotein binding by mast-cell granules. Demonstration of binding of apolipoprotein B to heparin proteoglycan of exocytosed granulesQ42855316
Regulation of cholesterol synthesis and storage in fat cellsQ51673608
Mast cells in human aortaQ66994688
Low density lipoprotein degradation by rat mast cells. Demonstration of extracellular proteolysis caused by mast cell granulesQ69913624
Degradation of the heparin matrix of mast cell granules by cultured fibroblastsQ71831691
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectlipoproteinQ28350
mast cellQ191989
P1104number of pages5
P304page(s)2287-2291
P577publication date1987-04-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStimulation of mast cells leads to cholesterol accumulation in macrophages in vitro by a mast cell granule-mediated uptake of low density lipoprotein
P478volume84

Reverse relations

cites work (P2860)
Q64276506Acute and Chronic Effects of Cocaine on Cardiovascular Health
Q37739235Biochemistry of the arterial wall in developing atherosclerosis
Q26825467Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases
Q35014223Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice.
Q78257763Immunological modulation of human cardiac mast cells
Q36705726Macrophages and Oxidized Low Density Lipoproteins in the Pathogenesis of Atherosclerosis
Q40159308Management of atherosclerosis with antiallergic medicine: a lesson from the mouse model
Q28388340Manufactured and airborne nanoparticle cardiopulmonary interactions: a review of mechanisms and the possible contribution of mast cells
Q58153662Mast Cell Granule-Mediated Uptake of Low Density Lipoproteins by Macrophages: A Novel Carrier Mechanism Leading to the Formation of Foam Cells
Q90079376Mast Cells as Potential Accelerators of Human Atherosclerosis-From Early to Late Lesions
Q91802489Mast Cells in Cardiovascular Disease: From Bench to Bedside
Q37578873Mast cell chymase and tryptase as targets for cardiovascular and metabolic diseases
Q37312777Mast cells and acute coronary syndromes: relationship between serum tryptase, clinical outcome and severity of coronary artery disease
Q35106076Mast cells and metabolic syndrome
Q99419174Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts
Q26995160Mast cells as effectors in atherosclerosis
Q38563903Mast cells in human and experimental cardiometabolic diseases
Q38007884Mast cells: an expanding pathophysiological role from allergy to other disorders
Q42796812Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages
Q41162467Oxidative modification of low-density lipoprotein by the human hepatoma cell line HepG2.
Q33850346Phagocytosis of aggregated lipoprotein by macrophages: low density lipoprotein receptor-dependent foam-cell formation
Q41048276Proteoglycans in macrophages: characterization and possible role in the cellular uptake of lipoproteins
Q35557630Regulation of smooth muscle cell growth, function and death in vitro by activated mast cells--a potential mechanism for the weakening and rupture of atherosclerotic plaques
Q51835824The Innate Immune Response in Myocardial Infarction, Repair, and Regeneration.
Q39270949Transcriptional Profiling Confirms the Therapeutic Effects of Mast Cell Stabilization in a Dengue Disease Model

Search more.