Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA.

scientific article

Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA. is …
instance of (P31):
scholarly articleQ13442814

External links are
P932PMC publication ID1462761
P698PubMed publication ID14504216

P50authorCory D DunnQ57327452
P2093author name stringRobert E Jensen
P2860cites workMolecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70Q24338681
Functional profiling of the Saccharomyces cerevisiae genomeQ27860544
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiaeQ27860636
Yeast COQ4 encodes a mitochondrial protein required for coenzyme Q synthesisQ27929495
The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamineQ27930850
Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranesQ27931290
The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channelQ27931318
The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membraneQ27931625
Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22.Q27933337
TOR, a central controller of cell growthQ27933354
Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membraneQ27933650
RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8pQ27934646
Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channelQ27935135
Genome-wide responses to mitochondrial dysfunctionQ27935978
A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23.Q27936312
Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membraneQ27936327
TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathwayQ27936370
Ssh1p determines the translocation and dislocation capacities of the yeast endoplasmic reticulumQ27936816
Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylationQ27938490
Molecular evolution of the HSP70 multigene familyQ27940113
Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeastQ28117160
Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applicationsQ28131600
A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coliQ28131613
Molecular chaperones in the cytosol: from nascent chain to folded proteinQ28205903
The petite mutation in yeasts: 50 years on.Q33737165
How membrane proteins travel across the mitochondrial intermembrane spaceQ33763330
Both ATP and an energized inner membrane are required to import a purified precursor protein into mitochondriaQ33929086
The in vivo function of the ribosome-associated Hsp70, Ssz1, does not require its putative peptide-binding domainQ34046935
The protein import motor of mitochondriaQ34142481
Delivery of nascent polypeptides to the mitochondrial surfaceQ34793169
Molecular chaperones as essential mediators of mitochondrial biogenesisQ34793186
Mitochondrial processing peptidasesQ34793194
Import and assembly of proteins into mitochondria of mammalian cellsQ34793219
Suppression of growth and protein secretion defects in Escherichia coli secA mutants by decreasing protein synthesisQ36296829
Spontaneous release of cytosolic proteins from posttranslational substrates before their transport into the endoplasmic reticulumQ36358019
The unique hetero-oligomeric nature of the subunits in the catalytic cooperativity of the yeast Cct chaperonin complexQ36595095
Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encoding genes, causes increased escape of DNA from mitochondria in Saccharomyces cerevisiaeQ36699218
A multitude of suppressors of group II intron-splicing defects in yeastQ36757121
Mutations in cognate genes of Saccharomyces cerevisiae hsp70 result in reduced growth rates at low temperaturesQ36953193
Multiple signals from dysfunctional mitochondria activate the pleiotropic drug resistance pathway in Saccharomyces cerevisiae.Q38308495
Regulation of the yeast CYT1 gene encoding cytochrome c1 by HAP1 and HAP2/3/4Q40640994
Genetic and biochemical basis for viability of yeast lacking mitochondrial genomes.Q41844258
Expression of the Saccharomyces cerevisiae gene YME1 in the petite-negative yeast Schizosaccharomyces pombe converts it to petite-positiveQ41902437
Mutations in the mitochondrial ATP synthase gamma subunit suppress a slow-growth phenotype of yme1 yeast lacking mitochondrial DNA.Q42921948
Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequencesQ43507030
SRP samples nascent chains for the presenceof signal sequences by interacting with ribosomes at a discrete step during translation elongationQ46378191
Gene overexpression in studies of Saccharomyces cerevisiae.Q54082674
Transfer of proteins into mitochondria. Precursor to the ADP/ATP carrier binds to receptor sites on isolated mitochondriaQ62996739
The role of adenine nucleotide translocation in the energization of the inner membrane of mitochondria isolated from rho + and rho degree strains of Saccharomyces cerevisiaeQ69921208
The petite mutation in yeast. Loss of mitochondrial deoxyribonucleic acid during induction of petites with ethidium bromideQ71608524
Oxidative phosphorylation in yeast. IV. Combination of a nuclear mutation affecting oxidative phosphorylation with cytoplasmic mutation to respiratory deficiencyQ72118312
Requirement of a Membrane Potential for the Posttranslational Transfer of Proteins into MitochondsriaQ72762095
Alpha and beta subunits of F1-ATPase are required for survival of petite mutants in Saccharomyces cerevisiaeQ73340664
The absence of the mitochondrial ATP synthase delta subunit promotes a slow growth phenotype of rho- yeast cells by a lack of assembly of the catalytic sector F1Q73414419
Cytosolic factors mediate protein insertion into the peroxisomal membraneQ73717653
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmitochondrial DNAQ27075
mitochondrionQ39572
P1104number of pages11
P304page(s)35-45
P577publication date2003-09-01
P1433published inGeneticsQ3100575
P1476titleSuppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA
P478volume165

Reverse relations

cites work (P2860)
Q40717951A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death
Q27937167A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex
Q26829511Cell biology of spinocerebellar ataxia
Q27934449Characterization of Mmp37p, a Saccharomyces cerevisiae mitochondrial matrix protein with a role in mitochondrial protein import
Q36784779Defects associated with mitochondrial DNA damage can be mitigated by increased vacuolar pH in Saccharomyces cerevisiae
Q37543961Deletion of conserved protein phosphatases reverses defects associated with mitochondrial DNA damage in Saccharomyces cerevisiae
Q39218296Exploring genetic suppression interactions on a global scale
Q34232888Formation of an energized inner membrane in mitochondria with a gamma-deficient F1-ATPase
Q84581757Identification of genes related to nitrogen uptake in wine strains of Saccharomyces cerevisiae
Q40148229Identifying novel protein phenotype annotations by hybridizing protein-protein interactions and protein sequence similarities.
Q27932282Isc1 regulates sphingolipid metabolism in yeast mitochondria.
Q27933251Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex
Q40129343Mitochondrial Cochaperone Mge1 Is Involved in Regulating Susceptibility to Fluconazole in Saccharomyces cerevisiae and Candida Species.
Q37380849Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect
Q36895018Mitochondrial genome integrity mutations uncouple the yeast Saccharomyces cerevisiae ATP synthase
Q38513065Predicting gene function in a hierarchical context with an ensemble of classifiers
Q90626242Reciprocal interactions between mtDNA and lifespan control in budding yeast
Q35890030Reduced Glucose Sensation Can Increase the Fitness of Saccharomyces cerevisiae Lacking Mitochondrial DNA.
Q27937005Rpm2p, a component of yeast mitochondrial RNase P, acts as a transcriptional activator in the nucleus
Q34692029Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase
Q38224024Sphingolipids and mitochondrial function in budding yeast
Q51189818The Aspergillus nidulans Pbp1 homolog is required for normal sexual development and secondary metabolism.
Q27936487Tim54p connects inner membrane assembly and proteolytic pathways in the mitochondrion
Q42138105Trypanosoma brucei: differential requirement of membrane potential for import of proteins into mitochondria in two developmental stages
Q27314605dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1
Q47579528mPOS is a novel mitochondrial trigger of cell death - implications for neurodegeneration

Search more.